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A1DEZ0 (SHO1_NEOFI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
High osmolarity signaling protein sho1
Alternative name(s):
Osmosensor sho1
Gene names
Name:sho1
ORF Names:NFIA_078870
OrganismNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus) [Complete proteome]
Taxonomic identifier331117 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya

Protein attributes

Sequence length288 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity By similarity.

Subunit structure

Forms homooligomers By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the SHO1 family.

Contains 1 SH3 domain.

Ontologies

Keywords
   Biological processStress response
   Cellular componentCell membrane
Membrane
   DomainSH3 domain
Transmembrane
Transmembrane helix
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processresponse to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 288288High osmolarity signaling protein sho1
PRO_0000410385

Regions

Topological domain1 – 1414Cytoplasmic Potential
Transmembrane15 – 3521Helical; Potential
Topological domain36 – 449Extracellular Potential
Transmembrane45 – 6521Helical; Potential
Topological domain66 – 705Cytoplasmic Potential
Transmembrane71 – 9121Helical; Potential
Topological domain92 – 10312Extracellular Potential
Transmembrane104 – 12421Helical; Potential
Topological domain125 – 288164Cytoplasmic Potential
Domain229 – 28860SH3

Amino acid modifications

Glycosylation441N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A1DEZ0 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: EA78E63B915E092F

FASTA28830,802
        10         20         30         40         50         60 
MAKFRASNIL GDPFALATVS ISILAWLIAC IASIISDIKT DYPNYSWWAV AYMFCCIIGV 

        70         80         90        100        110        120 
TIVFGSDTGL VYGVAVVGYL STGLVLTTLA VNTLVYADES SSQAAAAGFI LLSMVIVVWI 

       130        140        150        160        170        180 
FYFGSSPQAT HRGFIDSFAL NKESSGAYGN RPMSTAFGPR PDTMSTSAPQ MYTSAQLNGF 

       190        200        210        220        230        240 
ETSSPVSGYP GGAPGSENRS SSQARFGNPS ASNVTGNNNG QDEVPQPTEY PYKAKAIYSY 

       250        260        270        280 
DANPEDANEI SFSKHEILEV SDVSGRWWQA RKSNGETGIA PSNYLILL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS027696 Genomic DNA. Translation: EAW17947.1.
RefSeqXP_001259844.1. XM_001259843.1.

3D structure databases

ProteinModelPortalA1DEZ0.
SMRA1DEZ0. Positions 230-288.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING36630.CADNFIAP00006786.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADNFIAT00006953; CADNFIAP00006786; CADNFIAG00006953.
GeneID4585757.
KEGGnfi:NFIA_078870.

Phylogenomic databases

HOGENOMHOG000174182.
KOK11246.
OMADAYEISF.
OrthoDBEOG7MPRR4.

Family and domain databases

InterProIPR001452. SH3_domain.
[Graphical view]
PfamPF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSPR00452. SH3DOMAIN.
SMARTSM00326. SH3. 1 hit.
[Graphical view]
SUPFAMSSF50044. SSF50044. 1 hit.
PROSITEPS50002. SH3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSHO1_NEOFI
AccessionPrimary (citable) accession number: A1DEZ0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 28, 2011
Last sequence update: January 23, 2007
Last modified: February 19, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families