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A1DEZ0

- SHO1_NEOFI

UniProt

A1DEZ0 - SHO1_NEOFI

Protein

High osmolarity signaling protein sho1

Gene

sho1

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.By similarity

    GO - Biological processi

    1. response to stress Source: UniProtKB-KW

    Keywords - Biological processi

    Stress response

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    High osmolarity signaling protein sho1
    Alternative name(s):
    Osmosensor sho1
    Gene namesi
    Name:sho1
    ORF Names:NFIA_078870
    OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
    Taxonomic identifieri331117 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya
    ProteomesiUP000006702: Unassembled WGS sequence

    Subcellular locationi

    Cell membrane By similarity; Multi-pass membrane protein By similarity

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 288288High osmolarity signaling protein sho1PRO_0000410385Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi44 – 441N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Interactioni

    Subunit structurei

    Forms homooligomers.By similarity

    Protein-protein interaction databases

    STRINGi36630.CADNFIAP00006786.

    Structurei

    3D structure databases

    ProteinModelPortaliA1DEZ0.
    SMRiA1DEZ0. Positions 230-288.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 1414CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini36 – 449ExtracellularSequence Analysis
    Topological domaini66 – 705CytoplasmicSequence Analysis
    Topological domaini92 – 10312ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini125 – 288164CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei15 – 3521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei45 – 6521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei71 – 9121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei104 – 12421HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini229 – 28860SH3PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the SHO1 family.Curated
    Contains 1 SH3 domain.PROSITE-ProRule annotation

    Keywords - Domaini

    SH3 domain, Transmembrane, Transmembrane helix

    Phylogenomic databases

    HOGENOMiHOG000174182.
    KOiK11246.
    OMAiDAYEISF.
    OrthoDBiEOG7MPRR4.

    Family and domain databases

    InterProiIPR001452. SH3_domain.
    [Graphical view]
    PfamiPF00018. SH3_1. 1 hit.
    [Graphical view]
    PRINTSiPR00452. SH3DOMAIN.
    SMARTiSM00326. SH3. 1 hit.
    [Graphical view]
    SUPFAMiSSF50044. SSF50044. 1 hit.
    PROSITEiPS50002. SH3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1DEZ0-1 [UniParc]FASTAAdd to Basket

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    MAKFRASNIL GDPFALATVS ISILAWLIAC IASIISDIKT DYPNYSWWAV    50
    AYMFCCIIGV TIVFGSDTGL VYGVAVVGYL STGLVLTTLA VNTLVYADES 100
    SSQAAAAGFI LLSMVIVVWI FYFGSSPQAT HRGFIDSFAL NKESSGAYGN 150
    RPMSTAFGPR PDTMSTSAPQ MYTSAQLNGF ETSSPVSGYP GGAPGSENRS 200
    SSQARFGNPS ASNVTGNNNG QDEVPQPTEY PYKAKAIYSY DANPEDANEI 250
    SFSKHEILEV SDVSGRWWQA RKSNGETGIA PSNYLILL 288
    Length:288
    Mass (Da):30,802
    Last modified:January 23, 2007 - v1
    Checksum:iEA78E63B915E092F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027696 Genomic DNA. Translation: EAW17947.1.
    RefSeqiXP_001259844.1. XM_001259843.1.

    Genome annotation databases

    EnsemblFungiiCADNFIAT00006953; CADNFIAP00006786; CADNFIAG00006953.
    GeneIDi4585757.
    KEGGinfi:NFIA_078870.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027696 Genomic DNA. Translation: EAW17947.1 .
    RefSeqi XP_001259844.1. XM_001259843.1.

    3D structure databases

    ProteinModelPortali A1DEZ0.
    SMRi A1DEZ0. Positions 230-288.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 36630.CADNFIAP00006786.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADNFIAT00006953 ; CADNFIAP00006786 ; CADNFIAG00006953 .
    GeneIDi 4585757.
    KEGGi nfi:NFIA_078870.

    Phylogenomic databases

    HOGENOMi HOG000174182.
    KOi K11246.
    OMAi DAYEISF.
    OrthoDBi EOG7MPRR4.

    Family and domain databases

    InterProi IPR001452. SH3_domain.
    [Graphical view ]
    Pfami PF00018. SH3_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00452. SH3DOMAIN.
    SMARTi SM00326. SH3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50044. SSF50044. 1 hit.
    PROSITEi PS50002. SH3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181.

    Entry informationi

    Entry nameiSHO1_NEOFI
    AccessioniPrimary (citable) accession number: A1DEZ0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 28, 2011
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3