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A1DEV5 (BTGC_NEOFI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glucan endo-1,3-beta-glucosidase btgC

EC=3.2.1.39
Alternative name(s):
Endo-1,3-beta-glucanase btgC
Laminarinase btgC
Gene names
Name:btgC
ORF Names:NFIA_078520
OrganismNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus) [Complete proteome]
Taxonomic identifier331117 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya

Protein attributes

Sequence length689 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan By similarity.

Catalytic activity

Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.

Subcellular location

Cell membrane; Single-pass type II membrane protein By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 17 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 689689Probable glucan endo-1,3-beta-glucosidase btgC
PRO_0000395129

Regions

Topological domain1 – 307307Cytoplasmic Potential
Transmembrane308 – 32821Helical; Signal-anchor for type II membrane protein; Potential
Topological domain329 – 689361Extracellular Potential
Compositional bias254 – 33683Gly-rich
Compositional bias341 – 35010Poly-Ser

Sites

Active site5901Nucleophile By similarity
Active site6581Proton donor By similarity

Amino acid modifications

Glycosylation4081N-linked (GlcNAc...) Potential
Glycosylation4311N-linked (GlcNAc...) Potential
Glycosylation4591N-linked (GlcNAc...) Potential
Glycosylation6091N-linked (GlcNAc...) Potential
Glycosylation6351N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A1DEV5 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: BBFC912E985B68F4

FASTA68972,601
        10         20         30         40         50         60 
MSGPNRTYSF GEGDDGLAHP SSRTHAMHSQ YDDVSPISDG ARMNPMNGQG TDHGLASVPE 

        70         80         90        100        110        120 
DGHQGWGRGP EPSPSILTGS SATPGMDNLG PGAVGGGISG IALSVANSHD RLSGVEALMG 

       130        140        150        160        170        180 
TDGQEANIPA ERGFSTTGSD NPYVPAPPEH RYSYGSNIAL GAAAAPAGQL TPGQSVSHLS 

       190        200        210        220        230        240 
SSNPSQRNLY DIPYQGAGGL NAGPYQRHSA YSSNDLPVDI NPDEIVDDGD DGFVPAPNSS 

       250        260        270        280        290        300 
SSARKSQAIP AAAGGAAAGG FLGNLGGLFG GKSAADTSYG PVPGAGLEAG EKGRWVKPKP 

       310        320        330        340        350        360 
GGGSKKRGWI VGAILAFIII GAIVGGAVGG TIGHRGNEEP SSASSSSSSS TQTATDDTST 

       370        380        390        400        410        420 
NGDLDKNSAE IKALMNNKNL HKVFPGIDYT PWGVQYPLCL KYPPSQNNVT RDMAVLTQLT 

       430        440        450        460        470        480 
NNVRLYGTDC NQTEMVLHAI DKLEIKDMKI WLGVWIDSNI TTSRRQIDQL YKIIDDAKDT 

       490        500        510        520        530        540 
SIFNGAIVGN EALYRAGSDK TSAQTTLINY MQEVKDHFKK KNIDLPVATS DLGDNWDATL 

       550        560        570        580        590        600 
VQAADVVMAN VHPFFGGIPV DQAAAWTWQF WQDHNVALTK GTNKKQVISE VGWPSGGGND 

       610        620        630        640        650        660 
CGLGANCPND TAGAVAGVDE LNKFMEDWVC QALENGTDYF WFEAFDEPWK IVYNTANENW 

       670        680 
EDKWGLMDAA RNLKPGLKIP DCGGKTATR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS027696 Genomic DNA. Translation: EAW17912.1.
RefSeqXP_001259809.1. XM_001259808.1.

3D structure databases

ProteinModelPortalA1DEV5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADNFIAT00006952; CADNFIAP00006785; CADNFIAG00006952.
GeneID4585859.
KEGGnfi:NFIA_078520.

Phylogenomic databases

eggNOGCOG5309.
HOGENOMHOG000173877.
OMASDNPYVP.
OrthoDBEOG7P8PHC.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
ProtoNetSearch...

Entry information

Entry nameBTGC_NEOFI
AccessionPrimary (citable) accession number: A1DEV5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: January 23, 2007
Last modified: February 19, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries