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Protein

Hexokinase

Gene

NFIA_025000

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. kinase activity Source: UniProtKB-KW
  3. phosphotransferase activity, alcohol group as acceptor Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:NFIA_025000Imported
OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)Imported
Taxonomic identifieri331117 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya
ProteomesiUP000006702: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi36630.CADNFIAP00002346.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 1 hexokinase type-2 domain.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000179996.
KOiK00844.
OMAiILPLTRW.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.

Sequencei

Sequence statusi: Complete.

A1DC68-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAPLVKVLH RMQELFSNIV AALEAMILFP SLFRDPSRKR RKAFHGAYWR
60 70 80 90 100
RRTLDNFAEE VDRLFTAPLS LRNMIIMSEK IREQFKSCLQ SSPVCMLPSY
110 120 130 140 150
NHALPSGTEK GTYLALDVGG STFRVALIEL GGAGAMKILQ ESSSPIDNDV
160 170 180 190 200
KLLEGTLFFD WMAEKIESML SAVGADYGRE AVPLSMGLSW SFPIEQTSIS
210 220 230 240 250
SGLVIHMGKG FLCSNGTLGQ ELGDLIVQSC RRRSLNVRVD AIVNDSSAAL
260 270 280 290 300
LSRAYVDPKT RMSLILGTGT NVAVHFPVHE IGLTKFGTRP PGWFDYAKHV
310 320 330 340 350
IINSELSMFG GGILPMTRWD DILNRTHLRP DYQPLEYMVT GRYLGEIVRL
360 370 380 390 400
IIAEAVETAN LFGGELPHSM RDPYSFDTSI VAFLEADTSP SLVPSAALLQ
410 420 430 440 450
KEHTFPVSPS VEDLRFLRRI CQIVSKRAAG YLATAIHSMW CLRNDAEFSD
460 470 480 490 500
PTESKASSVK DTQEITIVES EEDSRSLSIA CDGSVINKYP GFRDRSQEYL
510 520 530 540
NQLTQQTNSS QGSLDPATSP YIRLELAPES AILGAAVAVA VAVADQK
Length:547
Mass (Da):60,357
Last modified:January 23, 2007 - v1
Checksum:iEFCAB878EE3A471F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027695 Genomic DNA. Translation: EAW19428.1.
RefSeqiXP_001261325.1. XM_001261324.1.

Genome annotation databases

EnsemblFungiiCADNFIAT00002418; CADNFIAP00002346; CADNFIAG00002418.
GeneIDi4588193.
KEGGinfi:NFIA_025000.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027695 Genomic DNA. Translation: EAW19428.1.
RefSeqiXP_001261325.1. XM_001261324.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi36630.CADNFIAP00002346.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADNFIAT00002418; CADNFIAP00002346; CADNFIAG00002418.
GeneIDi4588193.
KEGGinfi:NFIA_025000.

Phylogenomic databases

HOGENOMiHOG000179996.
KOiK00844.
OMAiILPLTRW.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181Imported.

Entry informationi

Entry nameiA1DC68_NEOFI
AccessioniPrimary (citable) accession number: A1DC68
Entry historyi
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: March 4, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.