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Protein

Probable cutinase 3

Gene

NFIA_030250

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle.By similarity

Catalytic activityi

Cutin + H2O = cutin monomers.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei129 – 1291PROSITE-ProRule annotation
Active sitei184 – 1841PROSITE-ProRule annotation
Active sitei197 – 1971PROSITE-ProRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Serine esterase

Protein family/group databases

ESTHERiaspfu-q4w9z4. Cutinase.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cutinase 3 (EC:3.1.1.74)
Alternative name(s):
Cutin hydrolase 3
Gene namesi
ORF Names:NFIA_030250
OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Taxonomic identifieri331117 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya
Proteomesi
  • UP000006702 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:NFIA_030250.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Sequence analysisAdd
BLAST
Chaini18 – 217200Probable cutinase 3PRO_0000395265Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi39 ↔ 187By similarity
Disulfide bondi118 ↔ 180By similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliA1D9W1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cutinase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000171425.
KOiK08095.
OMAiFGFTRNV.
OrthoDBiEOG779P8P.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000675. Cutinase/axe.
IPR011150. Cutinase_monf.
[Graphical view]
PfamiPF01083. Cutinase. 1 hit.
[Graphical view]
PRINTSiPR00129. CUTINASE.
SMARTiSM01110. Cutinase. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00155. CUTINASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A1D9W1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLRSLFVAG LATLALAAPA PQIQARQGMS SNELESGPCR DVTFIFARGS
60 70 80 90 100
TEQGNMGFIV GPGVCSSLKN DLGSDKVACQ GVGGAYTAQL APNFLSQNTD
110 120 130 140 150
QASIDAATDM FDLANTKCPN TKIVAGGYSQ GSAVIDNAIQ ALDSDLKAKV
160 170 180 190 200
KGVVLFGFTR NVVDKGQIPG YPKDQTKIYC ALGDLVCDNT LIITAAHLSY
210
GADADDAAKF LASKVQG
Length:217
Mass (Da):22,490
Last modified:January 23, 2007 - v1
Checksum:iF43032A0DCD55299
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027693 Genomic DNA. Translation: EAW20592.1.
RefSeqiXP_001262489.1. XM_001262488.1.

Genome annotation databases

EnsemblFungiiCADNFIAT00002782; CADNFIAP00002705; CADNFIAG00002782.
GeneIDi4588994.
KEGGinfi:NFIA_030250.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027693 Genomic DNA. Translation: EAW20592.1.
RefSeqiXP_001262489.1. XM_001262488.1.

3D structure databases

ProteinModelPortaliA1D9W1.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

ESTHERiaspfu-q4w9z4. Cutinase.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADNFIAT00002782; CADNFIAP00002705; CADNFIAG00002782.
GeneIDi4588994.
KEGGinfi:NFIA_030250.

Organism-specific databases

EuPathDBiFungiDB:NFIA_030250.

Phylogenomic databases

HOGENOMiHOG000171425.
KOiK08095.
OMAiFGFTRNV.
OrthoDBiEOG779P8P.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000675. Cutinase/axe.
IPR011150. Cutinase_monf.
[Graphical view]
PfamiPF01083. Cutinase. 1 hit.
[Graphical view]
PRINTSiPR00129. CUTINASE.
SMARTiSM01110. Cutinase. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00155. CUTINASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181.

Entry informationi

Entry nameiCUTI3_NEOFI
AccessioniPrimary (citable) accession number: A1D9W1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 13, 2010
Last sequence update: January 23, 2007
Last modified: May 11, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.