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Protein

Probable endo-beta-1,4-glucanase celB

Gene

celB

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates (By similarity).By similarity

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei216NucleophileBy similarity1
Active sitei221Proton donorBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Probable endo-beta-1,4-glucanase celB (EC:3.2.1.4)
Short name:
Endoglucanase celB
Alternative name(s):
Carboxymethylcellulase celB
Cellulase B
Gene namesi
Name:celB
ORF Names:NFIA_114250
OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
Taxonomic identifieri331117 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006702 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:NFIA_114250

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_000039516019 – 407Probable endo-beta-1,4-glucanase celBAdd BLAST389

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi136N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiA1D932

Interactioni

Protein-protein interaction databases

STRINGi36630.CADNFIAP00010152

Structurei

3D structure databases

ProteinModelPortaliA1D932
SMRiA1D932
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000182210
KOiK19357
OMAiPWINGEA
OrthoDBiEOG092C29WB

Family and domain databases

CDDicd07999 GH7_CBH_EG, 1 hit
Gene3Di2.70.100.10, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR001722 Glyco_hydro_7
IPR037019 Glyco_hydro_7_sf
PANTHERiPTHR33753 PTHR33753, 1 hit
PfamiView protein in Pfam
PF00840 Glyco_hydro_7, 1 hit
PRINTSiPR00734 GLHYDRLASE7
SUPFAMiSSF49899 SSF49899, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A1D932-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALTLAATAL VLLPLVTAQQ IGSIAENHPE LTTYRCSSQA GCVAQSTSVV
60 70 80 90 100
LDINAHWIHQ NGAQTSCTTS SGLDPSLCPD KVTCSQNCVV EGITDYSSFG
110 120 130 140 150
VQNSGDAMTL RQYQVQNGQI KTLRPRVYLL AEDGINYSKL QLLNQEFTFD
160 170 180 190 200
VDASKLPCGM NGALYLSEMD ASGGRSALNP AGATYGTGYC DAQCFNPGPW
210 220 230 240 250
INGEANTAGA GACCQEMDLW EANSRSTIFS PHPCTTAGLY ACTGAECYSI
260 270 280 290 300
CDGYGCTYNP YELGAKDYYG YGLTIDTAKP ITVVTQFMTA DNTATGTLAE
310 320 330 340 350
IRRLYVQDGK VIGNTAVAMT EAFCSSSRTF EELGGLQRMG EALGRGMVPV
360 370 380 390 400
FSIWDDPGLW MHWLDSDGAG PCGNTEGDPA FIQANYPNTA VTFSKVRWGD

IGSTYSS
Length:407
Mass (Da):43,421
Last modified:January 23, 2007 - v1
Checksum:i022FA57ED78BA1D0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027692 Genomic DNA Translation: EAW20893.1
RefSeqiXP_001262790.1, XM_001262789.1

Genome annotation databases

EnsemblFungiiCADNFIAT00010428; CADNFIAP00010152; CADNFIAG00010428
GeneIDi4589309
KEGGinfi:NFIA_114250

Similar proteinsi

Entry informationi

Entry nameiCELB_NEOFI
AccessioniPrimary (citable) accession number: A1D932
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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