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Protein

Probable arabinogalactan endo-beta-1,4-galactanase A

Gene

galA

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Endogalactanase involved in the degradation of plant cell wall polysaccharides, and more particularly of hairy regions of pectin.By similarity

Catalytic activityi

The enzyme specifically hydrolyzes (1->4)-beta-D-galactosidic linkages in type I arabinogalactans.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei157Proton donorBy similarity1
Active sitei268NucleophileBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Cell wall biogenesis/degradation, Polysaccharide degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Probable arabinogalactan endo-beta-1,4-galactanase A (EC:3.2.1.89)
Alternative name(s):
Endo-1,4-beta-galactanase A
Short name:
Galactanase A
Gene namesi
Name:galA
ORF Names:NFIA_017780
OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
Taxonomic identifieri331117 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006702 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:NFIA_017780

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_000039495222 – 356Probable arabinogalactan endo-beta-1,4-galactanase AAdd BLAST335

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi133N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi36630.CADNFIAP00002039

Structurei

3D structure databases

ProteinModelPortaliA1D3T4
SMRiA1D3T4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 53 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000217077
KOiK01224
OMAiGVNTVRQ
OrthoDBiEOG092C2PF8

Family and domain databases

InterProiView protein in InterPro
IPR011683 Glyco_hydro_53
IPR017853 Glycoside_hydrolase_SF
PANTHERiPTHR34983 PTHR34983, 1 hit
PfamiView protein in Pfam
PF07745 Glyco_hydro_53, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A1D3T4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGKMILLPL FVLLCHSLAS ASLAYRGADI SSLLIEEKAG IKYKDVNGQA
60 70 80 90 100
QPLENILKAN GVNSVRQRVW VNPSDGSYNL DYNVKLAKRV KAAGMSVYLD
110 120 130 140 150
LHFSDTWADP SHQTTPRGWS TNDIGTLTWQ VYNYTKEVCD TFASNGIDVS
160 170 180 190 200
IVAIGNEIRN GLLWPLGKPN NYANIANILH SAAFGVKDST LSPKPKIMIH
210 220 230 240 250
LDNGWDWSAQ KFFYDSVLSS GAKLVKSDFD LIGVSYYPFY NPSATLSALT
260 270 280 290 300
TSLKNLRSTY GKDVLVVETD WPVSCPNPAY AFPSDLKDIP FSVAGQKTFV
310 320 330 340 350
QRVANVVAQT PGGIGLYYWE PAWVQNAALG SSCADNLMVD WRTDQARTSL

SVFGTI
Length:356
Mass (Da):39,095
Last modified:January 23, 2007 - v1
Checksum:iCFF0E268EF4DDA54
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027688 Genomic DNA Translation: EAW23077.1
RefSeqiXP_001264974.1, XM_001264973.1

Genome annotation databases

EnsemblFungiiCADNFIAT00002078; CADNFIAP00002039; CADNFIAG00002078
GeneIDi4591274
KEGGinfi:NFIA_017780

Similar proteinsi

Entry informationi

Entry nameiGANA_NEOFI
AccessioniPrimary (citable) accession number: A1D3T4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health