ID   A1D2X0_NEOFI            Unreviewed;       463 AA.
AC   A1D2X0;
DT   23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   23-JAN-2007, sequence version 1.
DT   27-MAR-2024, entry version 98.
DE   SubName: Full=Histone-lysine n-methyltransferase, suv9 {ECO:0000313|EMBL:EAW22763.1};
GN   ORFNames=NFIA_014540 {ECO:0000313|EMBL:EAW22763.1};
OS   Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS   / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW22763.1, ECO:0000313|Proteomes:UP000006702};
RN   [1] {ECO:0000313|Proteomes:UP000006702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC   NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
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DR   EMBL; DS027688; EAW22763.1; -; Genomic_DNA.
DR   RefSeq; XP_001264660.1; XM_001264659.1.
DR   AlphaFoldDB; A1D2X0; -.
DR   STRING; 331117.A1D2X0; -.
DR   EnsemblFungi; EAW22763; EAW22763; NFIA_014540.
DR   GeneID; 4591776; -.
DR   KEGG; nfi:NFIA_014540; -.
DR   VEuPathDB; FungiDB:NFIA_014540; -.
DR   eggNOG; KOG1082; Eukaryota.
DR   HOGENOM; CLU_020840_11_1_1; -.
DR   OMA; DPEAVQC; -.
DR   OrthoDB; 5481936at2759; -.
DR   Proteomes; UP000006702; Unassembled WGS sequence.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0042054; F:histone methyltransferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   InterPro; IPR003616; Post-SET_dom.
DR   InterPro; IPR007728; Pre-SET_dom.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   PANTHER; PTHR46223:SF3; HISTONE H3 (LYS9) METHYLTRANSFERASE-RELATED; 1.
DR   PANTHER; PTHR46223; HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H; 1.
DR   Pfam; PF05033; Pre-SET; 1.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00317; SET; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50868; POST_SET; 1.
DR   PROSITE; PS50867; PRE_SET; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:EAW22763.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006702};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EAW22763.1}.
FT   DOMAIN          224..298
FT                   /note="Pre-SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50867"
FT   DOMAIN          301..427
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   DOMAIN          439..455
FT                   /note="Post-SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50868"
FT   REGION          63..84
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   463 AA;  51934 MW;  14F0EFF55C8568C2 CRC64;
     MTVIDLTLDS DSEDQRRLAV SVMSTSAKPR SALGLGNHNN PITFNSSTAN NAIANANTPN
     SNHVFIPKIQ NPSTPSPSPS SQQEAIGVVI PSPSRQLRKE IEKSGWVKAP PVTPEKTALS
     TEYYPIDAHE KRALKGAYPS ARKVKRSEIP FSIGTPGPIL ADRIPVQRQL HETLQRKLSK
     INGPPVTFAP GEEGLLADFA SNFEFVNSYI LRNGVSHIPV DFIAGCDCKK ICDPARCGCL
     EQDEESKEII VPYQRAQDNA RLLVLTPDFL KRTDIIIECS SKCTCDEQKC WNRVVQHGRT
     IRLEIFHTGN RGFGLRSPDW IRAGQFIDCY LGEVITKQEA DVREEVATSQ HGHSYLFELD
     FFHNDDEIYV VDGQKFGSPT RFMNHSCNPN CKLFPVTRTY GDERLYDLAF FSLHNIPPNT
     ELTFDYNPNW EEGKKVDPNA VRCLCGEKNC RGQLWPNQRK GTK
//