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A1D1E6

- AGDC_NEOFI

UniProt

A1D1E6 - AGDC_NEOFI

Protein

Probable alpha/beta-glucosidase agdC

Gene

agdC

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Glucosidase involved in the degradation of cellulosic biomass. Has both alpha- and beta-glucosidase activity By similarity.By similarity

    Catalytic activityi

    Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.
    Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei422 – 4221NucleophilePROSITE-ProRule annotation
    Active sitei425 – 4251By similarity
    Active sitei571 – 5711Proton donorBy similarity

    GO - Molecular functioni

    1. beta-glucosidase activity Source: UniProtKB-EC
    2. carbohydrate binding Source: InterPro
    3. maltose alpha-glucosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. polysaccharide catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cell wall biogenesis/degradation, Polysaccharide degradation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable alpha/beta-glucosidase agdC (EC:3.2.1.20, EC:3.2.1.21)
    Gene namesi
    Name:agdC
    ORF Names:NFIA_009180
    OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
    Taxonomic identifieri331117 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeNeosartorya
    ProteomesiUP000006702: Unassembled WGS sequence

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1414Sequence AnalysisAdd
    BLAST
    Chaini15 – 881867Probable alpha/beta-glucosidase agdCPRO_0000394920Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi171 – 1711N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi293 – 2931N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi373 – 3731N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi506 – 5061N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi572 – 5721N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi608 – 6081N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi742 – 7421N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi36630.CADNFIAP00000699.

    Structurei

    3D structure databases

    ProteinModelPortaliA1D1E6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 31 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG1501.
    HOGENOMiHOG000041175.
    KOiK01187.
    OMAiSGQYLEY.
    OrthoDBiEOG77T1CZ.

    Family and domain databases

    InterProiIPR011013. Gal_mutarotase_SF_dom.
    IPR000322. Glyco_hydro_31.
    IPR025887. Glyco_hydro_31_N_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF13802. Gal_mutarotas_2. 1 hit.
    PF01055. Glyco_hydro_31. 1 hit.
    [Graphical view]
    SUPFAMiSSF51445. SSF51445. 2 hits.
    SSF74650. SSF74650. 1 hit.
    PROSITEiPS00129. GLYCOSYL_HYDROL_F31_1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    A1D1E6-1 [UniParc]FASTAAdd to Basket

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    MLRSLLLLAP LVGAAVLGVR DNSQECPGYK ATNIREGRNS LTADLTLAGT    50
    PCNTYGTDLK NLKLLVEYQT DKRLHVKIYD ADEEVYQVPE SVLPRVDGKG 100
    GSGKKSALKF DYQANPFSFK VKRGGEVLFD TSGSNLIFQS QYLNLRTWLP 150
    EDPNLYGLGE HTDSLRLETT NYTRTLWNRD AYAIPEKTNL YGTHPVYYDH 200
    RGQDGTHGVF LLNSNGMDIK IDKTEDGKQY LEYNTLGGVF DFYFFTGATP 250
    KDASIEYAKV VGLPAMQSYW TFGFHQCRYG YRDVFEVAEV VYNYTQAKIP 300
    LETMWTDIDY MDRRRVFTLD PERFPLEKLR ELVTYLHNHN QRYIVMVDPA 350
    VSVSDNVGYN DGMEQGIFLQ TQNGSLYKGA VWPGVTAYPD WFHPDIQKYW 400
    NDQFAKFFDR KTGVDIDGLW IDMNEAANFC PYPCSDPEGY SRDNDLPPAA 450
    PPVRPSNPRP LPGFPGDFQP SSSSKRSTKG SKVGLPNRDL INPPYMIRNE 500
    AGSLSNKTIN TDIIHAGEGY AEYDTHNLYG TMMSSASRNA MQHRRPEVRP 550
    LVITRSTYAG AGAHVGHWLG DNISEWSKYR VSIAQMLAFA SMFQVPMIGS 600
    DVCGFGGNTT EELCARWARL GAFYTFFRNH NEITGIPQEF YRWPTVAESA 650
    RKAIDIRYRL LDYIYTAFHR QTQTGEPFLQ PMFYLYPKDK NTFSNQLQFF 700
    YGDAILVSPV TDGSQTSVDA YFPDDIFYDW HTGAALRGRG ANVTLGNIDV 750
    TEIPIHIRGG SIIPIRSESA MTTTELRKKG FELIIAPGLD GTASGSLYLD 800
    DGDSIEQRAT LELEFTYRKG RLRVKGKFGF RTDVKINAVT LLGQSAPASK 850
    SGSVASFDSG RQAVTIKTSL DLTGPSEIDL N 881
    Length:881
    Mass (Da):99,054
    Last modified:January 23, 2007 - v1
    Checksum:i8311042A49FCA1D0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027688 Genomic DNA. Translation: EAW22239.1.
    RefSeqiXP_001264136.1. XM_001264135.1.

    Genome annotation databases

    EnsemblFungiiCADNFIAT00000738; CADNFIAP00000699; CADNFIAG00000738.
    GeneIDi4591952.
    KEGGinfi:NFIA_009180.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027688 Genomic DNA. Translation: EAW22239.1 .
    RefSeqi XP_001264136.1. XM_001264135.1.

    3D structure databases

    ProteinModelPortali A1D1E6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 36630.CADNFIAP00000699.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADNFIAT00000738 ; CADNFIAP00000699 ; CADNFIAG00000738 .
    GeneIDi 4591952.
    KEGGi nfi:NFIA_009180.

    Phylogenomic databases

    eggNOGi COG1501.
    HOGENOMi HOG000041175.
    KOi K01187.
    OMAi SGQYLEY.
    OrthoDBi EOG77T1CZ.

    Family and domain databases

    InterProi IPR011013. Gal_mutarotase_SF_dom.
    IPR000322. Glyco_hydro_31.
    IPR025887. Glyco_hydro_31_N_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF13802. Gal_mutarotas_2. 1 hit.
    PF01055. Glyco_hydro_31. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51445. SSF51445. 2 hits.
    SSF74650. SSF74650. 1 hit.
    PROSITEi PS00129. GLYCOSYL_HYDROL_F31_1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181.

    Entry informationi

    Entry nameiAGDC_NEOFI
    AccessioniPrimary (citable) accession number: A1D1E6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 15, 2010
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3