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Protein

Aspartate aminotransferase

Gene

NFIA_105660

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseUniRule annotationImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate aminotransferaseUniRule annotation (EC:2.6.1.1UniRule annotation)
Gene namesi
ORF Names:NFIA_105660Imported
OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) (Aspergillus fischerianus)Imported
Taxonomic identifieri331117 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006702 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:NFIA_105660.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA1CWS6.
SMRiA1CWS6. Positions 29-428.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini57 – 424368Aminotran_1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000185898.
KOiK14455.
OMAiSWANHAA.
OrthoDBiEOG793BHW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11879. PTHR11879. 1 hit.
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSiPR00799. TRANSAMINASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1CWS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSTLRVASR QAASREASMR TVIIGARHAS AWSNVPQGPP DAILGITEAF
60 70 80 90 100
KADTFKEKIN LGVGAYRDDK GKPYVLPSVR AAEDKVVASR LDKEYAGITG
110 120 130 140 150
IPSFTKAAAE LAYGSDSAVI KEDRLVITQT ISGTGALRIG GAFLQRFYPH
160 170 180 190 200
AKKIYLPTPS WANHAAVFKD SGMDVASYRY YNKDTIGLDF EGLIADIKAA
210 220 230 240 250
PNNSIILLHA CAHNPTGVDP TQDQWRQISD VMKEKGHFAF FDMAYQGFAS
260 270 280 290 300
GNADRDAFAP RHFVKEGHNI ALCQSFAKNM GLYGERVGAF SLVCESAEEK
310 320 330 340 350
KRVDSQIKIL IRPFYSNPPV HGARIASTIM NDPELNQQWL GEVKGMADRI
360 370 380 390 400
IEMRALLKKN LEDLGSKHDW SHITSQIGMF AYTGLKPEQM EVLAKEHSVY
410 420
ATKDGRISVA GITSGNVKRL AEAIYKVTG
Length:429
Mass (Da):47,030
Last modified:January 23, 2007 - v1
Checksum:iD4E0B8A5449647BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027685 Genomic DNA. Translation: EAW25078.1.
RefSeqiXP_001266975.1. XM_001266974.1.

Genome annotation databases

EnsemblFungiiCADNFIAT00009979; CADNFIAP00009739; CADNFIAG00009979.
GeneIDi4593784.
KEGGinfi:NFIA_105660.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027685 Genomic DNA. Translation: EAW25078.1.
RefSeqiXP_001266975.1. XM_001266974.1.

3D structure databases

ProteinModelPortaliA1CWS6.
SMRiA1CWS6. Positions 29-428.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADNFIAT00009979; CADNFIAP00009739; CADNFIAG00009979.
GeneIDi4593784.
KEGGinfi:NFIA_105660.

Organism-specific databases

EuPathDBiFungiDB:NFIA_105660.

Phylogenomic databases

HOGENOMiHOG000185898.
KOiK14455.
OMAiSWANHAA.
OrthoDBiEOG793BHW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11879. PTHR11879. 1 hit.
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSiPR00799. TRANSAMINASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181Imported.

Entry informationi

Entry nameiA1CWS6_NEOFI
AccessioniPrimary (citable) accession number: A1CWS6
Entry historyi
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: June 8, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.