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A1CUR8 (BGLH_ASPCL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable beta-glucosidase H

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase H
Cellobiase H
Gentiobiase H
Gene names
Name:bglH
ORF Names:ACLA_087610
OrganismAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) [Complete proteome]
Taxonomic identifier344612 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length829 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose By similarity.

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family.

Contains 1 PA14 domain.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Cellular componentSecreted
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 829829Probable beta-glucosidase H
PRO_0000394876

Regions

Domain391 – 535145PA14

Sites

Active site2251 By similarity

Amino acid modifications

Glycosylation4161N-linked (GlcNAc...) Potential
Glycosylation4311N-linked (GlcNAc...) Potential
Glycosylation4731N-linked (GlcNAc...) Potential
Glycosylation6021N-linked (GlcNAc...) Potential
Glycosylation6271N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A1CUR8 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: F6CD19443ADAD23C

FASTA82990,774
        10         20         30         40         50         60 
MTAKFDVDHV LNSISEDDKI ALLSGTDFWH TYSIPEHNVP PIRTTDGPNG VRGTKFFAGV 

        70         80         90        100        110        120 
PAACLPCGTA LGATWDRDLL HKAGVLLGQE CLAKGAHCWL GPTINMQRSP LGGRGFESFA 

       130        140        150        160        170        180 
EDPHLSGTMA KSIILGCEST GVISAVKHYV GNDQEHERRA VDVMVTPRAL REIYLRPFQI 

       190        200        210        220        230        240 
VARDAHSGAL MTSYNKINGK HVVENPAMYD IIRKEWKWDP LIMSDWLGTY TTIDSLNAGL 

       250        260        270        280        290        300 
DLEMPGPSRY RGKYIESAVQ ARLVKQSTID QRARKVLEFA ARASQAPASA VESGRDYPED 

       310        320        330        340        350        360 
RALNREICGN SIVLLKNEDT LLPLPKKIKK IALIGSHVKT PAISGGGSAS LQPYYAVSLY 

       370        380        390        400        410        420 
DAIIEVLPDT EIIYETGAYA HKMLPVIDRM LSNAVIRFYN EPADKERTLL STEPVNNTAF 

       430        440        450        460        470        480 
QLMDYNTPGL NRTLFWATLD GEFTPDVSGL WDFGLTVFGT ATLYIDDEMV IDNTTQQTRG 

       490        500        510        520        530        540 
TAFFGKGTIQ EVGAKELTAG RTYKIRIEFG SANTSPIKAI GVVHFGGGAA HLGAFLHMDP 

       550        560        570        580        590        600 
EQMVRDAVKA ASEADYTILC TGLNRDWESE GFDRPDMDLP PRIDALISAV LDVAGDKTII 

       610        620        630        640        650        660 
VNQSGTPVMM PWSDRARAII QAWYGGNETG HGIADVLFGD VNPCAKLPLS WPADVRHNPA 

       670        680        690        700        710        720 
YLNSLSVGGR MLYGEDIYVG YRFYEKIGQV TLFPFGHGLS YTLFEVSPKV TVSPTAFTVE 

       730        740        750        760        770        780 
TPLSATVRIK NTGPVAGAQI LQLYVAAPTS ATPRPVKELQ GFSKVFLQSG EEKTVVISVD 

       790        800        810        820 
KYATSFWDGI EDMWKSEAGV YQVLIGTSSQ DIVARGEFTV DETTFWTGV 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS027060 Genomic DNA. Translation: EAW07055.1.
RefSeqXP_001268481.1. XM_001268480.1.

3D structure databases

ProteinModelPortalA1CUR8.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADACLAT00007839; CADACLAP00007648; CADACLAG00007839.
GeneID4699856.
KEGGact:ACLA_087610.

Phylogenomic databases

eggNOGCOG1472.
HOGENOMHOG000031215.
OMAGCESTGV.
OrthoDBEOG7H799Q.

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 2 hits.
InterProIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
IPR011658. PA14.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
PF07691. PA14. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SMARTSM00758. PA14. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
ProtoNetSearch...

Entry information

Entry nameBGLH_ASPCL
AccessionPrimary (citable) accession number: A1CUR8
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: January 23, 2007
Last modified: February 19, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries