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A1CSW3

- A1CSW3_ASPCL

UniProt

A1CSW3 - A1CSW3_ASPCL

Protein

DNA ligase

Gene

ACLA_080840

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    ORF Names:ACLA_080840Imported
    OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)Imported
    Taxonomic identifieri344612 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000006701: Unassembled WGS sequence

    Interactioni

    Protein-protein interaction databases

    STRINGi5057.CADACLAP00007835.

    Structurei

    3D structure databases

    ProteinModelPortaliA1CSW3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    HOGENOMiHOG000036006.
    KOiK10747.
    OMAiMVKMLEG.
    OrthoDBiEOG7TXKRG.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1CSW3-1 [UniParc]FASTAAdd to Basket

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    MADSKGRKQA TLGRFFGSSA DAPKGAPKKQ TTLAFSSKKD KKSDAAAEEP    50
    SSEQSPSVST AVAELKNGVD VKMEDIPKEA AVAQPNGSPS AKSLKREKSS 100
    DEDSDSDIQP AQKRRRKSSR GAEAAPTVRK KSPSPKSPKK RGGKAKEASP 150
    PAVIRKSSGE ETPEKESELS DEEELELVSD EEEDKPEVMT KTMEKVQATL 200
    KATGTEPYPD WKPRQPVPYA ALCKTFSLIE MTTKRLIILA HCSLFLRQVL 250
    RLTPQDLLPT VQLMINKLAA DYAGIELGIG ESFIMKAIGE STGRSLAVIK 300
    ADQHEIGDLG LVAAKSRSNQ PTMFKPKPLT VRGVHEGLLA IAKIQGQGSQ 350
    EKKISAIKKL LSAADAATVG KGVDITKDKG GPSEAKFIVR FLEGKLRLGL 400
    AEKTVLVALA QAVVAHEAAV KGEKLPTPEK MAQGEAVLKT VYSELPAYEV 450
    IIPAMLEHGL LDLPKVCKLQ PGVPIKPMLA KPTKSITEVL NRFEGKDFTC 500
    EYKYDGERAQ IHYVAPDAIK HYPGATATLQ RDSKGLSAIF SRNSEDLSKK 550
    YPDVLAKLDN WVKDGVKSFV LDCETVAWDM ENKKVLPFQQ LMTRKRKDVK 600
    AEDVKVKVCI FAFDLLFLNG EATVKKSLRD RRELLHSSFN VSEGEFQFAQ 650
    HGDTNDLEEI QTLLDDSVKA SCEGLMVKML DTEESGYEPS KRSRNWLKVK 700
    KDYLAGVGDS LDLVVLGAYH GRGKRTSVYG AFLLAAYNSS TQTYETVCNI 750
    GTGFSEAALE EFYQELSPLT IDRPKPFYSH STVPKDQPDV WFEPRLVWEV 800
    KTADLTLSPR YKAAADEFMG TAGGGKGVSL RFPRFIKSRD DKKPDQATTT 850
    RAVAEMYRKQ EAVLKESSGK GGVDDDFEY 879
    Length:879
    Mass (Da):96,493
    Last modified:January 23, 2007 - v1
    Checksum:iBC8CD85176BAA574
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027060 Genomic DNA. Translation: EAW06400.1.
    RefSeqiXP_001267826.1. XM_001267825.1.

    Genome annotation databases

    EnsemblFungiiCADACLAT00008026; CADACLAP00007835; CADACLAG00008026.
    GeneIDi4700145.
    KEGGiact:ACLA_080840.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027060 Genomic DNA. Translation: EAW06400.1 .
    RefSeqi XP_001267826.1. XM_001267825.1.

    3D structure databases

    ProteinModelPortali A1CSW3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5057.CADACLAP00007835.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADACLAT00008026 ; CADACLAP00007835 ; CADACLAG00008026 .
    GeneIDi 4700145.
    KEGGi act:ACLA_080840.

    Phylogenomic databases

    HOGENOMi HOG000036006.
    KOi K10747.
    OMAi MVKMLEG.
    OrthoDBi EOG7TXKRG.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1Imported.

    Entry informationi

    Entry nameiA1CSW3_ASPCL
    AccessioniPrimary (citable) accession number: A1CSW3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 23, 2007
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3