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A1CSW3

- A1CSW3_ASPCL

UniProt

A1CSW3 - A1CSW3_ASPCL

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Protein
DNA ligase
Gene
ACLA_080840
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:ACLA_080840Imported
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006701: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi5057.CADACLAP00007835.

Structurei

3D structure databases

ProteinModelPortaliA1CSW3.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000036006.
KOiK10747.
OMAiMVKMLEG.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1CSW3-1 [UniParc]FASTAAdd to Basket

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MADSKGRKQA TLGRFFGSSA DAPKGAPKKQ TTLAFSSKKD KKSDAAAEEP    50
SSEQSPSVST AVAELKNGVD VKMEDIPKEA AVAQPNGSPS AKSLKREKSS 100
DEDSDSDIQP AQKRRRKSSR GAEAAPTVRK KSPSPKSPKK RGGKAKEASP 150
PAVIRKSSGE ETPEKESELS DEEELELVSD EEEDKPEVMT KTMEKVQATL 200
KATGTEPYPD WKPRQPVPYA ALCKTFSLIE MTTKRLIILA HCSLFLRQVL 250
RLTPQDLLPT VQLMINKLAA DYAGIELGIG ESFIMKAIGE STGRSLAVIK 300
ADQHEIGDLG LVAAKSRSNQ PTMFKPKPLT VRGVHEGLLA IAKIQGQGSQ 350
EKKISAIKKL LSAADAATVG KGVDITKDKG GPSEAKFIVR FLEGKLRLGL 400
AEKTVLVALA QAVVAHEAAV KGEKLPTPEK MAQGEAVLKT VYSELPAYEV 450
IIPAMLEHGL LDLPKVCKLQ PGVPIKPMLA KPTKSITEVL NRFEGKDFTC 500
EYKYDGERAQ IHYVAPDAIK HYPGATATLQ RDSKGLSAIF SRNSEDLSKK 550
YPDVLAKLDN WVKDGVKSFV LDCETVAWDM ENKKVLPFQQ LMTRKRKDVK 600
AEDVKVKVCI FAFDLLFLNG EATVKKSLRD RRELLHSSFN VSEGEFQFAQ 650
HGDTNDLEEI QTLLDDSVKA SCEGLMVKML DTEESGYEPS KRSRNWLKVK 700
KDYLAGVGDS LDLVVLGAYH GRGKRTSVYG AFLLAAYNSS TQTYETVCNI 750
GTGFSEAALE EFYQELSPLT IDRPKPFYSH STVPKDQPDV WFEPRLVWEV 800
KTADLTLSPR YKAAADEFMG TAGGGKGVSL RFPRFIKSRD DKKPDQATTT 850
RAVAEMYRKQ EAVLKESSGK GGVDDDFEY 879
Length:879
Mass (Da):96,493
Last modified:January 23, 2007 - v1
Checksum:iBC8CD85176BAA574
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027060 Genomic DNA. Translation: EAW06400.1.
RefSeqiXP_001267826.1. XM_001267825.1.

Genome annotation databases

EnsemblFungiiCADACLAT00008026; CADACLAP00007835; CADACLAG00008026.
GeneIDi4700145.
KEGGiact:ACLA_080840.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027060 Genomic DNA. Translation: EAW06400.1 .
RefSeqi XP_001267826.1. XM_001267825.1.

3D structure databases

ProteinModelPortali A1CSW3.
ModBasei Search...

Protein-protein interaction databases

STRINGi 5057.CADACLAP00007835.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADACLAT00008026 ; CADACLAP00007835 ; CADACLAG00008026 .
GeneIDi 4700145.
KEGGi act:ACLA_080840.

Phylogenomic databases

HOGENOMi HOG000036006.
KOi K10747.
OMAi MVKMLEG.
OrthoDBi EOG7TXKRG.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1.

Entry informationi

Entry nameiA1CSW3_ASPCL
AccessioniPrimary (citable) accession number: A1CSW3
Entry historyi
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: May 14, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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