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A1CSW3

- A1CSW3_ASPCL

UniProt

A1CSW3 - A1CSW3_ASPCL

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Protein

DNA ligase

Gene

ACLA_080840

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:ACLA_080840Imported
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)Imported
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006701: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi5057.CADACLAP00007835.

Structurei

3D structure databases

ProteinModelPortaliA1CSW3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000036006.
KOiK10747.
OMAiMVKMLEG.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1CSW3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MADSKGRKQA TLGRFFGSSA DAPKGAPKKQ TTLAFSSKKD KKSDAAAEEP
60 70 80 90 100
SSEQSPSVST AVAELKNGVD VKMEDIPKEA AVAQPNGSPS AKSLKREKSS
110 120 130 140 150
DEDSDSDIQP AQKRRRKSSR GAEAAPTVRK KSPSPKSPKK RGGKAKEASP
160 170 180 190 200
PAVIRKSSGE ETPEKESELS DEEELELVSD EEEDKPEVMT KTMEKVQATL
210 220 230 240 250
KATGTEPYPD WKPRQPVPYA ALCKTFSLIE MTTKRLIILA HCSLFLRQVL
260 270 280 290 300
RLTPQDLLPT VQLMINKLAA DYAGIELGIG ESFIMKAIGE STGRSLAVIK
310 320 330 340 350
ADQHEIGDLG LVAAKSRSNQ PTMFKPKPLT VRGVHEGLLA IAKIQGQGSQ
360 370 380 390 400
EKKISAIKKL LSAADAATVG KGVDITKDKG GPSEAKFIVR FLEGKLRLGL
410 420 430 440 450
AEKTVLVALA QAVVAHEAAV KGEKLPTPEK MAQGEAVLKT VYSELPAYEV
460 470 480 490 500
IIPAMLEHGL LDLPKVCKLQ PGVPIKPMLA KPTKSITEVL NRFEGKDFTC
510 520 530 540 550
EYKYDGERAQ IHYVAPDAIK HYPGATATLQ RDSKGLSAIF SRNSEDLSKK
560 570 580 590 600
YPDVLAKLDN WVKDGVKSFV LDCETVAWDM ENKKVLPFQQ LMTRKRKDVK
610 620 630 640 650
AEDVKVKVCI FAFDLLFLNG EATVKKSLRD RRELLHSSFN VSEGEFQFAQ
660 670 680 690 700
HGDTNDLEEI QTLLDDSVKA SCEGLMVKML DTEESGYEPS KRSRNWLKVK
710 720 730 740 750
KDYLAGVGDS LDLVVLGAYH GRGKRTSVYG AFLLAAYNSS TQTYETVCNI
760 770 780 790 800
GTGFSEAALE EFYQELSPLT IDRPKPFYSH STVPKDQPDV WFEPRLVWEV
810 820 830 840 850
KTADLTLSPR YKAAADEFMG TAGGGKGVSL RFPRFIKSRD DKKPDQATTT
860 870
RAVAEMYRKQ EAVLKESSGK GGVDDDFEY
Length:879
Mass (Da):96,493
Last modified:January 23, 2007 - v1
Checksum:iBC8CD85176BAA574
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027060 Genomic DNA. Translation: EAW06400.1.
RefSeqiXP_001267826.1. XM_001267825.1.

Genome annotation databases

EnsemblFungiiCADACLAT00008026; CADACLAP00007835; CADACLAG00008026.
GeneIDi4700145.
KEGGiact:ACLA_080840.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027060 Genomic DNA. Translation: EAW06400.1 .
RefSeqi XP_001267826.1. XM_001267825.1.

3D structure databases

ProteinModelPortali A1CSW3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5057.CADACLAP00007835.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADACLAT00008026 ; CADACLAP00007835 ; CADACLAG00008026 .
GeneIDi 4700145.
KEGGi act:ACLA_080840.

Phylogenomic databases

HOGENOMi HOG000036006.
KOi K10747.
OMAi MVKMLEG.
OrthoDBi EOG7TXKRG.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1Imported.

Entry informationi

Entry nameiA1CSW3_ASPCL
AccessioniPrimary (citable) accession number: A1CSW3
Entry historyi
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3