Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA ligase

Gene

ACLA_080840

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotationImported
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:ACLA_080840Imported
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)Imported
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006701 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:ACLA_080840

Interactioni

Protein-protein interaction databases

STRINGi5057.CADACLAP00007835

Structurei

3D structure databases

ProteinModelPortaliA1CSW3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini601 – 738DNA_LIGASE_A3InterPro annotationAdd BLAST138

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000036006
KOiK10747
OMAiWIKYKRD
OrthoDBiEOG092C0FHN

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
InterProiView protein in InterPro
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

A1CSW3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADSKGRKQA TLGRFFGSSA DAPKGAPKKQ TTLAFSSKKD KKSDAAAEEP
60 70 80 90 100
SSEQSPSVST AVAELKNGVD VKMEDIPKEA AVAQPNGSPS AKSLKREKSS
110 120 130 140 150
DEDSDSDIQP AQKRRRKSSR GAEAAPTVRK KSPSPKSPKK RGGKAKEASP
160 170 180 190 200
PAVIRKSSGE ETPEKESELS DEEELELVSD EEEDKPEVMT KTMEKVQATL
210 220 230 240 250
KATGTEPYPD WKPRQPVPYA ALCKTFSLIE MTTKRLIILA HCSLFLRQVL
260 270 280 290 300
RLTPQDLLPT VQLMINKLAA DYAGIELGIG ESFIMKAIGE STGRSLAVIK
310 320 330 340 350
ADQHEIGDLG LVAAKSRSNQ PTMFKPKPLT VRGVHEGLLA IAKIQGQGSQ
360 370 380 390 400
EKKISAIKKL LSAADAATVG KGVDITKDKG GPSEAKFIVR FLEGKLRLGL
410 420 430 440 450
AEKTVLVALA QAVVAHEAAV KGEKLPTPEK MAQGEAVLKT VYSELPAYEV
460 470 480 490 500
IIPAMLEHGL LDLPKVCKLQ PGVPIKPMLA KPTKSITEVL NRFEGKDFTC
510 520 530 540 550
EYKYDGERAQ IHYVAPDAIK HYPGATATLQ RDSKGLSAIF SRNSEDLSKK
560 570 580 590 600
YPDVLAKLDN WVKDGVKSFV LDCETVAWDM ENKKVLPFQQ LMTRKRKDVK
610 620 630 640 650
AEDVKVKVCI FAFDLLFLNG EATVKKSLRD RRELLHSSFN VSEGEFQFAQ
660 670 680 690 700
HGDTNDLEEI QTLLDDSVKA SCEGLMVKML DTEESGYEPS KRSRNWLKVK
710 720 730 740 750
KDYLAGVGDS LDLVVLGAYH GRGKRTSVYG AFLLAAYNSS TQTYETVCNI
760 770 780 790 800
GTGFSEAALE EFYQELSPLT IDRPKPFYSH STVPKDQPDV WFEPRLVWEV
810 820 830 840 850
KTADLTLSPR YKAAADEFMG TAGGGKGVSL RFPRFIKSRD DKKPDQATTT
860 870
RAVAEMYRKQ EAVLKESSGK GGVDDDFEY
Length:879
Mass (Da):96,493
Last modified:January 23, 2007 - v1
Checksum:iBC8CD85176BAA574
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027060 Genomic DNA Translation: EAW06400.1
RefSeqiXP_001267826.1, XM_001267825.1

Genome annotation databases

EnsemblFungiiCADACLAT00008026; CADACLAP00007835; CADACLAG00008026
GeneIDi4700145
KEGGiact:ACLA_080840

Entry informationi

Entry nameiA1CSW3_ASPCL
AccessioniPrimary (citable) accession number: A1CSW3
Entry historyiIntegrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health