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A1CR85 (BGLA_ASPCL) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable beta-glucosidase A

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase A
Cellobiase A
Gentiobiase A
Gene names
Name:bglA
Synonyms:bgl1
ORF Names:ACLA_028810
OrganismAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) [Complete proteome]
Taxonomic identifier344612 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length867 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose By similarity.

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Chain19 – 867849Probable beta-glucosidase A
PRO_0000394092

Sites

Active site2871 By similarity

Amino acid modifications

Glycosylation671N-linked (GlcNAc...) Potential
Glycosylation2181N-linked (GlcNAc...) Potential
Glycosylation2591N-linked (GlcNAc...) Potential
Glycosylation3221N-linked (GlcNAc...) Potential
Glycosylation3291N-linked (GlcNAc...) Potential
Glycosylation3611N-linked (GlcNAc...) Potential
Glycosylation4491N-linked (GlcNAc...) Potential
Glycosylation5301N-linked (GlcNAc...) Potential
Glycosylation5491N-linked (GlcNAc...) Potential
Glycosylation5711N-linked (GlcNAc...) Potential
Glycosylation6751N-linked (GlcNAc...) Potential
Glycosylation7191N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A1CR85 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 6E9D96C46B830BA5

FASTA86794,053
        10         20         30         40         50         60 
MRFSWLEVAV TAASLANANV CIPLFPWYVS SPPFYPSPWA NGQGEWAEAH QRAVEIVSQM 

        70         80         90        100        110        120 
TLTEKVNLTT GTGWMMEECV GQTGSVPRLG INWGLCGQDS PLGIRFSDLN SAFPAGINVA 

       130        140        150        160        170        180 
ATWDKTLAYL RGKAMGEEFN DKGIDIQLGP AAGPLGKYPD GGRIWEGFSP DPALTGVLFA 

       190        200        210        220        230        240 
ETIKGIQDAG VIATAKHYIL NEQEQFRQVA EAQGYGYNIT ETLSSNVDDK TMHELYLWPF 

       250        260        270        280        290        300 
ADAVRAGVGA IMCSYNQINN SYGCQNSQTL NKLLKAELGF QGFVMSDWSA HHSGVGAALA 

       310        320        330        340        350        360 
GLDMSMPGDI SFDDGLSFWG ANMTVGVLNG TIPAWRVDDM AVRIMTAYYK VGRDRLRVPP 

       370        380        390        400        410        420 
NFSSWTRDEY GYEHAAVSEG AWKKVNDFVN VQRDHAQLIR EVGSASTVLL KNVGALPLTG 

       430        440        450        460        470        480 
KERKVGIFGE DAGSNPWGPN GCENRGCDNG TLAMAWGSGT AEFPYLVTPE QAIQSEVIKN 

       490        500        510        520        530        540 
GGNVFPVTHN GALTQMANIA SQSSVSLVFV NADAGEGFIS VDGNIGDRKN LTLWKNGEEV 

       550        560        570        580        590        600 
IKTVASHSNN TVVVIHSVGP ILVDEWHDNP NITAILWAGL PGQESGNSIA DVLYGRVNPS 

       610        620        630        640        650        660 
AKTPFTWGKT RESYGAPLVT KPNNGNGAPQ DDFSEGVFID YRYFDKRNET PVYEFGFGLS 

       670        680        690        700        710        720 
YTSFGYSHLR VQPLNGSTYV PATGTTGPAP AYGSIGSAAD YLFPEGLKRI TKFIYPWLNS 

       730        740        750        760        770        780 
TDLKASSADP NYGWEDSEYI PEAATDGSPQ PILKAGGAPG GNPTLYHDLV KVSATITNTG 

       790        800        810        820        830        840 
NVAGYEVPQL YVSLGGPNEP RVVLRKFDRI HLAPGEQKVW TTTLTRRDLA NWDVEAQDWV 

       850        860 
ITKYPKRVYV GSSSRKLPLR APLPRVQ 

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS027059 Genomic DNA. Translation: EAW08156.1.
RefSeqXP_001269582.1. XM_001269581.1.

3D structure databases

ProteinModelPortalA1CR85.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5057.CADACLAP00002846.

Proteomic databases

PRIDEA1CR85.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADACLAT00002893; CADACLAP00002846; CADACLAG00002893.
GeneID4701004.
KEGGact:ACLA_028810.

Phylogenomic databases

eggNOGCOG1472.
HOGENOMHOG000031215.
KOK05349.
OMAAHHSGVG.
OrthoDBEOG7HMS8F.

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
PROSITEPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBGLA_ASPCL
AccessionPrimary (citable) accession number: A1CR85
Entry history
Integrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: January 23, 2007
Last modified: November 13, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries