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Protein

Hexokinase

Gene

ACLA_098220

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. fructokinase activity Source: EnsemblFungi
  3. glucokinase activity Source: EnsemblFungi
  4. mannokinase activity Source: EnsemblFungi

GO - Biological processi

  1. fructose 6-phosphate metabolic process Source: EnsemblFungi
  2. glycolytic fermentation Source: EnsemblFungi
  3. glycolytic process Source: UniProtKB-KW
  4. mannose metabolic process Source: EnsemblFungi
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:ACLA_098220Imported
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)Imported
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006701 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:ACLA_098220.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: EnsemblFungi
  2. nucleus Source: EnsemblFungi
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi5057.CADACLAP00008933.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000162670.
KOiK00844.
OMAiMIPRELM.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1CMU3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSPLVEEAT RIAQLFHYPA EKIQLGVKEF IREMSEGLTK EHTTLSQIPT
60 70 80 90 100
YVTSVPNGTE KGLYLAVDLG GTNFRVCSID LHGDTTFNLT QSKIMIPREM
110 120 130 140 150
MASGTSKDLF LFLARQIESF LRIHHNEHFE AHLRRRRDPD HEEELFDLGF
160 170 180 190 200
TFSFPVRQLG INKGTLIRWT KGFNIPDAVG HDVCALLQNA IDELNLPVRV
210 220 230 240 250
AALVNDTVGT LMARSYTSPG ETGTFIGAIF GTGTNGAYVE KLNRITKLQT
260 270 280 290 300
MEHSNYETCT GEMIVNTEWG SFDNHLSVLP NTKWDQELDE ESNNPGIQMF
310 320 330 340 350
EKRVSGMFLG EILRRALIDM HQDKSVGLFT PSDTSDVVVP ENSPIYRQWG
360 370 380 390 400
IDTSFLSLVE ADKTEAMEEV KAALKDHLKI ERPSMDDCRV VQILVHAVGK
410 420 430 440 450
RAARLSAIPL AAILISTGKI EEDMVDIGVD GSLVEFYPNF EGHIRDALRE
460 470 480 490
VPEMGSAGEK KVRIGISKDG SGVGAALIAL VASRGDVSPA SK
Length:492
Mass (Da):54,464
Last modified:January 23, 2007 - v1
Checksum:iF2F169070F09B4B2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027058 Genomic DNA. Translation: EAW08880.1.
RefSeqiXP_001270306.1. XM_001270305.1.

Genome annotation databases

EnsemblFungiiCADACLAT00009157; CADACLAP00008933; CADACLAG00009157.
GeneIDi4702487.
KEGGiact:ACLA_098220.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027058 Genomic DNA. Translation: EAW08880.1.
RefSeqiXP_001270306.1. XM_001270305.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5057.CADACLAP00008933.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADACLAT00009157; CADACLAP00008933; CADACLAG00009157.
GeneIDi4702487.
KEGGiact:ACLA_098220.

Organism-specific databases

EuPathDBiFungiDB:ACLA_098220.

Phylogenomic databases

HOGENOMiHOG000162670.
KOiK00844.
OMAiMIPRELM.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1Imported.

Entry informationi

Entry nameiA1CMU3_ASPCL
AccessioniPrimary (citable) accession number: A1CMU3
Entry historyi
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: April 29, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.