A1CLD2 (BUD32_ASPCL) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 37.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Serine/threonine-protein kinase bud32 EC=2.7.11.1 | ||||
| Gene names |
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| Organism | Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) [Complete proteome] | ||||
| Taxonomic identifier | 344612 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus |
Protein attributes
| Sequence length | 277 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Component of the EKC/KEOPS complex which promotes both telomere uncapping and telomere elongation By similarity. The complex is required for efficient recruitment of transcriptional coactivators. Important for bud site selection By similarity. |
| Catalytic activity | ATP + a protein = ADP + a phosphoprotein. |
| Subunit structure | Component of the EKC/KEOPS complex By similarity. |
| Subcellular location | Cytoplasm By similarity. Nucleus By similarity. Chromosome › telomere By similarity. |
| Sequence similarities | Belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily. Contains 1 protein kinase domain. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 277 | 277 | Serine/threonine-protein kinase bud32 | PRO_0000278905 | |||||
Regions | |||||||||
| Domain | 20 – 277 | 258 | Protein kinase | ||||||
| Nucleotide binding | 26 – 34 | 9 | ATP By similarity | ||||||
Sites | |||||||||
| Active site | 172 | 1 | Proton acceptor By similarity | ||||||
| Binding site | 49 | 1 | ATP By similarity | ||||||
Sequences
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References
| [1] | "Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus." Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J., Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H., Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M. Nierman W.C.PLoS Genet. 4:E1000046-E1000046(2008) [PubMed: 18404212] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | DS027056 Genomic DNA. Translation: EAW09956.1. |
| RefSeq | XP_001271382.1. XM_001271381.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A1CLD2. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblFungi | CADACLAT00003372; CADACLAP00003292; CADACLAG00003372. |
| GeneID | 4703225. |
| KEGG | act:ACLA_041780. |
Phylogenomic databases | |
| GeneTree | EFGT00050000005785. |
| OrthoDB | EOG4R7ZKZ. |
Family and domain databases | |
| InterPro | IPR022495. Kinase-assoc_endopept-1. IPR011009. Kinase-like_dom. IPR010440. LipoPS_kinase. IPR000719. Prot_kinase_cat_dom. IPR008266. Tyr_kinase_AS. [Graphical view] |
| KO | K08851. |
| Pfam | PF06293. Kdo. 1 hit. [Graphical view] |
| SUPFAM | SSF56112. Kinase_like. 1 hit. |
| TIGRFAMs | TIGR03724. Arch_bud32. 1 hit. |
| PROSITE | PS00107. PROTEIN_KINASE_ATP. False negative. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00109. PROTEIN_KINASE_TYR. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BUD32_ASPCL | ||||||||
| Accession | Primary (citable) accession number: A1CLD2 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

Clusters with