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A1CHV7

- PRTT_ASPCL

UniProt

A1CHV7 - PRTT_ASPCL

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Protein

Transcriptional activator of proteases prtT

Gene

prtT

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Transcription factor required for protein utilization and degradation. Regulates transcription of major secreted proteases (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi54 – 8330Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: InterPro
  3. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional activator of proteases prtT
Alternative name(s):
Zn(2)-C6 zinc finger-containing protein prtT
Gene namesi
Name:prtT
ORF Names:ACLA_049340
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006701: Unassembled WGS sequence

Subcellular locationi

Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 622622Transcriptional activator of proteases prtTPRO_0000407030Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi5057.CADACLAP00004482.

Structurei

3D structure databases

ProteinModelPortaliA1CHV7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the prtT family.Curated
Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG81463.
HOGENOMiHOG000190417.
OMAiINHAIIS.
OrthoDBiEOG75MW59.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1CHV7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTRTTTLEEV KFEIPTWDNN NHIEVADGSG RSESNASGDT IRPKGRIRRS
60 70 80 90 100
MTACNTCRKL KTRCDLDPRG HACRRCLSLR IECKLPDTAE RFQDNASMWS
110 120 130 140 150
DATAAIPSIE ERLNSLERSM TEMTSMMRQM VDRSPSISGS SVSLLTRSGL
160 170 180 190 200
TEETASVEGS QPSFIAPRPI RLIQELQSDF LGEPNVLPAE SRSLSESFSN
210 220 230 240 250
GVLDPKLSLK LIQLFVEHFG SWVSIDSPSD IHNDLRPTDP LLYRTACLLA
260 270 280 290 300
SRYVPGIPSS VIQAEYLQIR HAAVNILWNS QPMKYETLQA LTLLSLWPTT
310 320 330 340 350
IQKEAPMDSW LLSGISINHA IISFDFLNHA PAELIVDNDM VAKLRLWNAL
360 370 380 390 400
CLTQLQFAIG NARPFHIQQR YLEHCPRLLE HPAATFDDGK MVAEIQLYLV
410 420 430 440 450
TSKLQNDPHR MRSAEIEYEE IERWKMEWAH LLTGEQHSTL ELNLWYCQLL
460 470 480 490 500
LYRTAMKCQW ESEPLVSEVL RNARLIISKF LLVRFSTALG FVDQTYYIVG
510 520 530 540 550
YAALNLCDFN PMDPLIDQVQ TFLLHLSPNE DHIAYRFSYT ISELKRRCTA
560 570 580 590 600
CPNPNSAVKG AFGDARKLNL GQLHFMPQVL DTMMGDYSAL EQLMPEVSPH
610 620
SLPDMLNNVT GELQAGYRTA IL
Length:622
Mass (Da):70,510
Last modified:January 23, 2007 - v1
Checksum:iDF638C4A0D263433
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027054 Genomic DNA. Translation: EAW10462.1.
RefSeqiXP_001271888.1. XM_001271887.1.

Genome annotation databases

EnsemblFungiiCADACLAT00004583; CADACLAP00004482; CADACLAG00004583.
GeneIDi4703912.
KEGGiact:ACLA_049340.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027054 Genomic DNA. Translation: EAW10462.1 .
RefSeqi XP_001271888.1. XM_001271887.1.

3D structure databases

ProteinModelPortali A1CHV7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5057.CADACLAP00004482.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADACLAT00004583 ; CADACLAP00004482 ; CADACLAG00004583 .
GeneIDi 4703912.
KEGGi act:ACLA_049340.

Phylogenomic databases

eggNOGi NOG81463.
HOGENOMi HOG000190417.
OMAi INHAIIS.
OrthoDBi EOG75MW59.

Family and domain databases

Gene3Di 4.10.240.10. 1 hit.
InterProi IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view ]
Pfami PF00172. Zn_clus. 1 hit.
[Graphical view ]
SMARTi SM00066. GAL4. 1 hit.
[Graphical view ]
SUPFAMi SSF57701. SSF57701. 1 hit.
PROSITEi PS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1.

Entry informationi

Entry nameiPRTT_ASPCL
AccessioniPrimary (citable) accession number: A1CHV7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3