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Protein
Submitted name:

Ras guanine-nucleotide exchange protein, putative

Gene

ACLA_045850

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. guanyl-nucleotide exchange factor activity Source: InterPro

GO - Biological processi

  1. regulation of small GTPase mediated signal transduction Source: InterPro
  2. small GTPase mediated signal transduction Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ras guanine-nucleotide exchange protein, putativeImported
Gene namesi
ORF Names:ACLA_045850Imported
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)Imported
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006701: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi5057.CADACLAP00004824.

Structurei

3D structure databases

ProteinModelPortaliA1CGW5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 SH3 domain.UniRule annotation
Contains N-terminal Ras-GEF domain.SAAS annotation
Contains Ras-GEF domain.SAAS annotation

Keywords - Domaini

SH3 domainUniRule annotation

Phylogenomic databases

HOGENOMiHOG000188111.
OMAiSIHTNGW.
OrthoDBiEOG78WM2F.

Family and domain databases

Gene3Di1.10.840.10. 1 hit.
InterProiIPR000651. Ras-like_Gua-exchang_fac_N.
IPR023578. Ras_GEF_dom.
IPR001895. RASGEF_cat_dom.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00617. RasGEF. 1 hit.
PF00618. RasGEF_N. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
SMARTiSM00147. RasGEF. 1 hit.
SM00229. RasGEFN. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48366. SSF48366. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS50009. RASGEF_CAT. 1 hit.
PS50212. RASGEF_NTER. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1CGW5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGPMKRHIAP LKIDKAISNH SVTTSGTGHS SSNRCYSTQH NLQMSPPLTP
60 70 80 90 100
YSATSNQDDS MERSDQPRAV FHNYLRAFYP FHQPGDVSPA TITLPLEQGD
110 120 130 140 150
IILVHSVHTN GWADGTLLDT GARGWLPTNY CEAYDQLPMR PLLKALTDFW
160 170 180 190 200
DIIRGGCGSS LRDFVNQDLL KGLIAGVRIL LVSTSNRPNN IKGNNAINIE
210 220 230 240 250
QDKSECLTRD SYLLKRHDSL RRNRKTLLSD LAALVRITKD FQVIASGNPL
260 270 280 290 300
EDEVEYMLDE MLLKAFRLVT RGVRFLDIWT EEVGLSRTIA ELEQPKAYEG
310 320 330 340 350
PLTPASETFT LSDVARSEAD IERNESRLLN RGRLSMSRAS NRMDVLEQSR
360 370 380 390 400
PVSVTTKRIS ISHRVSYSGP AAAARNPNLA SERLNATYDA FLGVLGSFIG
410 420 430 440 450
LHLQSRSSTE LVVTTEQAVR SCRGLLTVVE AVCEHDPRGS ELLDPAKDSM
460 470 480 490 500
YERLSELVFA ARDAFRPAQS PDDELVFMPD EGKRLVDAAT DCVRAAGNCL
510 520 530 540 550
SKARLVLEQT GDLELEALPQ EVTPTDCARP GSQSEQQVGD QTGASLRLPP
560 570 580 590 600
PPLQIPQHND MHVPPPTPGL TEDTTPSSCN SRTMDSPANA AADLPSFSST
610 620 630 640 650
TTLATSPVKT SFCSSTNSGA CGSSMLLDRT SHAKFEVDES FGRGVTSTGS
660 670 680 690 700
SFTYHSHLRD SEMSGVSQTS TRATSPDIGS NYQAPSLKGS TSHSTLAEEA
710 720 730 740 750
DETEVNILEK TYAHELIFKD GQIMGGSLRA LIEKLTANGS TPDAMFVSAF
760 770 780 790 800
YLTFRLFATP LEFAESLVER FDYIGDTPYA AGPVRLRVYN VFKGWLESHW
810 820 830 840 850
RHDCDTSALE FIVTFAKTAL MQSLPSAGKR LLELTDKVSA LQGPVVPRLV
860 870 880 890 900
SSMGKTNTAT AQYVHPDTPL PPPILGKKEV NLLKQWKNGD GALSILDFDP
910 920 930 940 950
MELARQLTIK ESRIFCTILP EELLATEWMK KTASLAVNVR AMSTLSTDLA
960 970 980 990 1000
HLVADSILQL EEPKKRAAII KHWVKIANKC LELNNYDSLM AIICSLNSSM
1010 1020 1030 1040 1050
ISRLRRTWEV VSHKTKTTLE MLRGIVDVSR NYAVLRQRLQ GHVPPCLPFV
1060 1070 1080 1090 1100
GTYLTDLTFV DHGNQALRSL PIDDGEMAVI NFDKHMKTAK IISELQRFQI
1110 1120 1130 1140 1150
PYRLTEVPEL QTWMQNELVR VRSNGEKSLQ TFYRRSLVLE PRETPQRPTL
1160 1170 1180
QAEVSSSSAS ILENAKDKFD LFSWTYPSKA KSVATHG
Length:1,187
Mass (Da):131,324
Last modified:January 23, 2007 - v1
Checksum:i31C1991E1588A319
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027054 Genomic DNA. Translation: EAW10120.1.
RefSeqiXP_001271546.1. XM_001271545.1.

Genome annotation databases

EnsemblFungiiCADACLAT00004925; CADACLAP00004824; CADACLAG00004925.
GeneIDi4704157.
KEGGiact:ACLA_045850.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027054 Genomic DNA. Translation: EAW10120.1.
RefSeqiXP_001271546.1. XM_001271545.1.

3D structure databases

ProteinModelPortaliA1CGW5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5057.CADACLAP00004824.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADACLAT00004925; CADACLAP00004824; CADACLAG00004925.
GeneIDi4704157.
KEGGiact:ACLA_045850.

Phylogenomic databases

HOGENOMiHOG000188111.
OMAiSIHTNGW.
OrthoDBiEOG78WM2F.

Family and domain databases

Gene3Di1.10.840.10. 1 hit.
InterProiIPR000651. Ras-like_Gua-exchang_fac_N.
IPR023578. Ras_GEF_dom.
IPR001895. RASGEF_cat_dom.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00617. RasGEF. 1 hit.
PF00618. RasGEF_N. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
SMARTiSM00147. RasGEF. 1 hit.
SM00229. RasGEFN. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48366. SSF48366. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS50009. RASGEF_CAT. 1 hit.
PS50212. RASGEF_NTER. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1Imported.

Entry informationi

Entry nameiA1CGW5_ASPCL
AccessioniPrimary (citable) accession number: A1CGW5
Entry historyi
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: February 4, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.