Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A1CG87

- CELB_ASPCL

UniProt

A1CG87 - CELB_ASPCL

Protein

Probable endo-beta-1,4-glucanase celB

Gene

celB

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (23 Jan 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates By similarity.By similarity

    Catalytic activityi

    Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei215 – 2151NucleophileBy similarity
    Active sitei220 – 2201Proton donorBy similarity

    GO - Molecular functioni

    1. cellulase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable endo-beta-1,4-glucanase celB (EC:3.2.1.4)
    Short name:
    Endoglucanase celB
    Alternative name(s):
    Carboxymethylcellulase celB
    Cellulase B
    Gene namesi
    Name:celB
    ORF Names:ACLA_066030
    OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
    Taxonomic identifieri344612 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000006701: Unassembled WGS sequence

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1818Sequence AnalysisAdd
    BLAST
    Chaini19 – 418400Probable endo-beta-1,4-glucanase celBPRO_0000395153Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi46 – 461N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi118 – 1181N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi136 – 1361N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi234 – 2341N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi291 – 2911N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Structurei

    3D structure databases

    ProteinModelPortaliA1CG87.
    SMRiA1CG87. Positions 19-414.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiNOG138370.
    HOGENOMiHOG000182210.
    OMAiEGHADDI.
    OrthoDBiEOG7Q8CXJ.

    Family and domain databases

    Gene3Di2.70.100.10. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR001722. Glyco_hydro_7.
    [Graphical view]
    PfamiPF00840. Glyco_hydro_7. 1 hit.
    [Graphical view]
    PRINTSiPR00734. GLHYDRLASE7.
    SUPFAMiSSF49899. SSF49899. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    A1CG87-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVRTFAVTAL ALLPLVAAQQ IGSTKEVHPQ LTTYKCTSQG GCVKQNTSIV    50
    LDSGSHWIHA KGGEVSCTTS SGLDPALCPD KETCAENCVV EGITDYSQYG 100
    VQTRGDAMLL REYIKQNNQT KAPSPRVYLL DEDGENYSML RLLNQEFTFD 150
    VDVSKLPCGM NGALYFSEMS ASGGRSALNP AGAAYGTGYC DAQCYTNAWI 200
    NGEANTAKAG LCCQEMDIWE ANARANAFTP HPCNSTGLLG CAGDECNSVC 250
    DKAGCGFNPY ALGARDYYGT AMTVDTTKPF TVVTQFLTAD NSTTGALREI 300
    RRLYVQAGQV IQNAVVKVDG RTVNSITEPY CASQGVFEGL GGLRRMGEAL 350
    GRGMVLSMSI WNDAGGFMHW LDSGNSGPCS STEGDPSLIE NKYPDTAVTF 400
    SKIRWGDLGT TFATRRLH 418
    Length:418
    Mass (Da):44,827
    Last modified:January 23, 2007 - v1
    Checksum:iC9607BB9C58EC80B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027053 Genomic DNA. Translation: EAW10967.1.
    RefSeqiXP_001272393.1. XM_001272392.1.

    Genome annotation databases

    EnsemblFungiiCADACLAT00006346; CADACLAP00006191; CADACLAG00006346.
    GeneIDi4704573.
    KEGGiact:ACLA_066030.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027053 Genomic DNA. Translation: EAW10967.1 .
    RefSeqi XP_001272393.1. XM_001272392.1.

    3D structure databases

    ProteinModelPortali A1CG87.
    SMRi A1CG87. Positions 19-414.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADACLAT00006346 ; CADACLAP00006191 ; CADACLAG00006346 .
    GeneIDi 4704573.
    KEGGi act:ACLA_066030.

    Phylogenomic databases

    eggNOGi NOG138370.
    HOGENOMi HOG000182210.
    OMAi EGHADDI.
    OrthoDBi EOG7Q8CXJ.

    Family and domain databases

    Gene3Di 2.70.100.10. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR001722. Glyco_hydro_7.
    [Graphical view ]
    Pfami PF00840. Glyco_hydro_7. 1 hit.
    [Graphical view ]
    PRINTSi PR00734. GLHYDRLASE7.
    SUPFAMi SSF49899. SSF49899. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1.

    Entry informationi

    Entry nameiCELB_ASPCL
    AccessioniPrimary (citable) accession number: A1CG87
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 15, 2010
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3