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Protein

Histone chaperone rtt106

Gene

rtt106

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone chaperone rtt106
Gene namesi
Name:rtt106
ORF Names:ACLA_088660
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006701 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:ACLA_088660.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003204821 – 463Histone chaperone rtt106Add BLAST463

Interactioni

Subunit structurei

Interacts with histones H3 and H4.By similarity

Protein-protein interaction databases

STRINGi5057.CADACLAP00008708.

Structurei

3D structure databases

ProteinModelPortaliA1CE78.
SMRiA1CE78.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RTT106 family.Curated

Phylogenomic databases

HOGENOMiHOG000048523.
OMAiCLPVPEK.
OrthoDBiEOG092C40DW.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiView protein in InterPro
IPR013719. DUF1747.
IPR011993. PH_dom-like.
PfamiView protein in Pfam
PF08512. Rtt106. 1 hit.
SMARTiView protein in SMART
SM01287. Rtt106. 1 hit.
SUPFAMiSSF50729. SSF50729. 1 hit.

Sequencei

Sequence statusi: Complete.

A1CE78-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVFATINRSA TKTVPATIPA IEEAFAAEPS LKKRVYDAIE NTPQYVPLFE
60 70 80 90 100
DIARYTSSLL ARPTNPPAQP AEASEGPAAK KRKLQNGTAA ANAQSPADVK
110 120 130 140 150
AETSLQFYMQ DVSFAMPQRK KLTLEITAGR GFLRARNQTS KEVEFGVPMD
160 170 180 190 200
RIRHVLCLPV PEKAQRQFNF CVIPQYSDGI NPPTEGEEVF ESMVWTISDG
210 220 230 240 250
PAKAAFSGTG QQIGNKEGET AESLVRRILN ENLSHIKVVR PDEREFVSAM
260 270 280 290 300
PEAHRKGEKA YHVKAFRGSK EGYLFFLSTG VFFGFKKPLV FFAFENIVSI
310 320 330 340 350
SYTSVLQRTF NLNIAVRSHN GAEDETQEFE LSMIDQADYA GIDAYIKKHG
360 370 380 390 400
LQDASLAEAR RAKRYNINGA KAEEDTTNNA EGAAAEEESE LQKAQRELED
410 420 430 440 450
QEDEDEEDYD PGSDGESEGS GSSSEDDDED DEDDEEDDDN EGDEDLVAAE
460
LGSEAEDVPQ DEL
Length:463
Mass (Da):51,196
Last modified:January 23, 2007 - v1
Checksum:i20BCB4CEA2F3103C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027052 Genomic DNA. Translation: EAW11177.1.
RefSeqiXP_001272603.1. XM_001272602.1.

Genome annotation databases

EnsemblFungiiCADACLAT00008918; CADACLAP00008708; CADACLAG00008918.
GeneIDi4705009.
KEGGiact:ACLA_088660.

Similar proteinsi

Entry informationi

Entry nameiRT106_ASPCL
AccessioniPrimary (citable) accession number: A1CE78
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: January 23, 2007
Last modified: August 30, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families