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A1CE78

- RT106_ASPCL

UniProt

A1CE78 - RT106_ASPCL

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Protein
Histone chaperone rtt106
Gene
rtt106, ACLA_088660
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing. Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter By similarity.

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Histone chaperone rtt106
Gene namesi
Name:rtt106
ORF Names:ACLA_088660
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006701: Unassembled WGS sequence

Subcellular locationi

Nucleus By similarity. Chromosome By similarity

GO - Cellular componenti

  1. chromosome Source: UniProtKB-SubCell
  2. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Chromosome, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 463463Histone chaperone rtt106
PRO_0000320482Add
BLAST

Interactioni

Subunit structurei

Interacts with histones H3 and H4 By similarity.

Protein-protein interaction databases

STRINGi5057.CADACLAP00008708.

Structurei

3D structure databases

ProteinModelPortaliA1CE78.

Family & Domainsi

Sequence similaritiesi

Belongs to the RTT106 family.

Phylogenomic databases

eggNOGiNOG78439.
HOGENOMiHOG000048523.
OMAiFNNIASF.
OrthoDBiEOG7TBCC0.

Family and domain databases

InterProiIPR013719. DUF1747.
[Graphical view]
PfamiPF08512. Rtt106. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1CE78-1 [UniParc]FASTAAdd to Basket

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MVFATINRSA TKTVPATIPA IEEAFAAEPS LKKRVYDAIE NTPQYVPLFE    50
DIARYTSSLL ARPTNPPAQP AEASEGPAAK KRKLQNGTAA ANAQSPADVK 100
AETSLQFYMQ DVSFAMPQRK KLTLEITAGR GFLRARNQTS KEVEFGVPMD 150
RIRHVLCLPV PEKAQRQFNF CVIPQYSDGI NPPTEGEEVF ESMVWTISDG 200
PAKAAFSGTG QQIGNKEGET AESLVRRILN ENLSHIKVVR PDEREFVSAM 250
PEAHRKGEKA YHVKAFRGSK EGYLFFLSTG VFFGFKKPLV FFAFENIVSI 300
SYTSVLQRTF NLNIAVRSHN GAEDETQEFE LSMIDQADYA GIDAYIKKHG 350
LQDASLAEAR RAKRYNINGA KAEEDTTNNA EGAAAEEESE LQKAQRELED 400
QEDEDEEDYD PGSDGESEGS GSSSEDDDED DEDDEEDDDN EGDEDLVAAE 450
LGSEAEDVPQ DEL 463
Length:463
Mass (Da):51,196
Last modified:January 23, 2007 - v1
Checksum:i20BCB4CEA2F3103C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027052 Genomic DNA. Translation: EAW11177.1.
RefSeqiXP_001272603.1. XM_001272602.1.

Genome annotation databases

EnsemblFungiiCADACLAT00008918; CADACLAP00008708; CADACLAG00008918.
GeneIDi4705009.
KEGGiact:ACLA_088660.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027052 Genomic DNA. Translation: EAW11177.1 .
RefSeqi XP_001272603.1. XM_001272602.1.

3D structure databases

ProteinModelPortali A1CE78.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5057.CADACLAP00008708.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADACLAT00008918 ; CADACLAP00008708 ; CADACLAG00008918 .
GeneIDi 4705009.
KEGGi act:ACLA_088660.

Phylogenomic databases

eggNOGi NOG78439.
HOGENOMi HOG000048523.
OMAi FNNIASF.
OrthoDBi EOG7TBCC0.

Family and domain databases

InterProi IPR013719. DUF1747.
[Graphical view ]
Pfami PF08512. Rtt106. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1.

Entry informationi

Entry nameiRT106_ASPCL
AccessioniPrimary (citable) accession number: A1CE78
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: January 23, 2007
Last modified: February 19, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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