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A1CBF1

- A1CBF1_ASPCL

UniProt

A1CBF1 - A1CBF1_ASPCL

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Protein
DNA ligase
Gene
ACLA_015070
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:ACLA_015070Imported
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006701: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi5057.CADACLAP00001394.

Structurei

3D structure databases

ProteinModelPortaliA1CBF1.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000176213.
KOiK10777.
OMAiHMCPSTK.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1CBF1-1 [UniParc]FASTAAdd to Basket

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MNSDDIGPDE GHPRAPVENE ESDLDEKYPN RPRNHSSTLP FHELFQTLFN     50
PLSEIKKKPA GAVAARRKVG PHGQSAANLN PLERRRDVIE RFISRWRKEV 100
GDDIYPAFRL ILPDKDRDRA MYGIKEKAIG KMLVKIMKID KNSEDGFNLL 150
NWKLPGQAAA TRMAGDFAGR CYDVLSKRPM RTDVGDMSIE EVNEKLDNLS 200
AASKEEQQLP ILAEFYRRMN PEELMWLIRI ILRQMKVGAT ERTFFDVWHP 250
DAENLYSISS SLRRVCWELH DPNIRLDAED RGISLMQCFQ PQLAQFQMQS 300
LDKMVSRMRP TEDDPVFWIE EKLDGERMQL HMESDDSVPG GRRFRFWSRK 350
AKEYTYLYGN GIYDENGSLT RHLKDAFADG VDSLILDGEM ITWDPEQDAP 400
APFGTLKTAA LAEQRNPFST TGARPLFRVF DILYLNGRDL TGYTLRDRRN 450
ALQKSVRPVH RRFEIHPYEE ATTKDEVEVA LRKVVAEASE GLVLKNPRSP 500
YRLNERHDDW MKVKPEYMTE FGESLDLIVI GGYFGSGRRG GNLSSFLCGL 550
RADDTHASQG SNASKCYSFC KVGGGFNAAD YANIRHHTDG KWVEWNPKKP 600
PTAYIELAGK DAQYERPDMW IKPEDSVVVC VKAASVSVSD QFRIGLTLRF 650
PRFKRLRMDK DWRSALSVQG FLDLKSNVEQ EHREKEFSVD NFRRKRIKRT 700
TKKPLAVAGY DADEEAKYAG PSGHIFEGLN FYILTDANAP VKKSKQELEQ 750
LVKANGGKFY QTNNAAPHTV CIADRRTVKA ASLQKSGNVD IIRPSWLLDC 800
VKQNEIDAGL PDLLLPMEPK HMFFARPEKQ EEVAANVDQF NDSYARNTTS 850
EELKNVLFLP NWWLRKTSAD CFKTLHQMMK EHRFKGSQCP EGIAKLTERI 900
QERVHSGYEI PCGWLFKGLT ILFQHRSMDD TGSSGNTVPS DHSYRLRLAI 950
NTARFAGANI ASSPNQASIT HVVVDPESPS SEISSLRGTW SKKQGQKVPH 1000
IVAVDWIEES WKERTLLDEE RFQPKRSKA 1029
Length:1,029
Mass (Da):117,611
Last modified:January 23, 2007 - v1
Checksum:i12350CBF4A8E68BA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027049 Genomic DNA. Translation: EAW13069.1.
RefSeqiXP_001274495.1. XM_001274494.1.

Genome annotation databases

EnsemblFungiiCADACLAT00001413; CADACLAP00001394; CADACLAG00001413.
GeneIDi4706930.
KEGGiact:ACLA_015070.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027049 Genomic DNA. Translation: EAW13069.1 .
RefSeqi XP_001274495.1. XM_001274494.1.

3D structure databases

ProteinModelPortali A1CBF1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5057.CADACLAP00001394.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADACLAT00001413 ; CADACLAP00001394 ; CADACLAG00001413 .
GeneIDi 4706930.
KEGGi act:ACLA_015070.

Phylogenomic databases

HOGENOMi HOG000176213.
KOi K10777.
OMAi HMCPSTK.
OrthoDBi EOG7QC84G.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 1 hit.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1.

Entry informationi

Entry nameiA1CBF1_ASPCL
AccessioniPrimary (citable) accession number: A1CBF1
Entry historyi
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: November 13, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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