A1CBF1 (A1CBF1_ASPCL) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

ORF Names:

ACLA_015070 EMBL EAW13069.1

Organism

Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) [Complete proteome]

Taxonomic identifier

344612 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus › Aspergillus clavatus

Protein attributes

Sequence length	1029 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617 EMBL EAW13069.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1CBF1 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: 12350CBF4A8E68BA	FASTA	1,029	117,611
	10 20 30 40 50 60 MNSDDIGPDE GHPRAPVENE ESDLDEKYPN RPRNHSSTLP FHELFQTLFN PLSEIKKKPA 70 80 90 100 110 120 GAVAARRKVG PHGQSAANLN PLERRRDVIE RFISRWRKEV GDDIYPAFRL ILPDKDRDRA 130 140 150 160 170 180 MYGIKEKAIG KMLVKIMKID KNSEDGFNLL NWKLPGQAAA TRMAGDFAGR CYDVLSKRPM 190 200 210 220 230 240 RTDVGDMSIE EVNEKLDNLS AASKEEQQLP ILAEFYRRMN PEELMWLIRI ILRQMKVGAT 250 260 270 280 290 300 ERTFFDVWHP DAENLYSISS SLRRVCWELH DPNIRLDAED RGISLMQCFQ PQLAQFQMQS 310 320 330 340 350 360 LDKMVSRMRP TEDDPVFWIE EKLDGERMQL HMESDDSVPG GRRFRFWSRK AKEYTYLYGN 370 380 390 400 410 420 GIYDENGSLT RHLKDAFADG VDSLILDGEM ITWDPEQDAP APFGTLKTAA LAEQRNPFST 430 440 450 460 470 480 TGARPLFRVF DILYLNGRDL TGYTLRDRRN ALQKSVRPVH RRFEIHPYEE ATTKDEVEVA 490 500 510 520 530 540 LRKVVAEASE GLVLKNPRSP YRLNERHDDW MKVKPEYMTE FGESLDLIVI GGYFGSGRRG 550 560 570 580 590 600 GNLSSFLCGL RADDTHASQG SNASKCYSFC KVGGGFNAAD YANIRHHTDG KWVEWNPKKP 610 620 630 640 650 660 PTAYIELAGK DAQYERPDMW IKPEDSVVVC VKAASVSVSD QFRIGLTLRF PRFKRLRMDK 670 680 690 700 710 720 DWRSALSVQG FLDLKSNVEQ EHREKEFSVD NFRRKRIKRT TKKPLAVAGY DADEEAKYAG 730 740 750 760 770 780 PSGHIFEGLN FYILTDANAP VKKSKQELEQ LVKANGGKFY QTNNAAPHTV CIADRRTVKA 790 800 810 820 830 840 ASLQKSGNVD IIRPSWLLDC VKQNEIDAGL PDLLLPMEPK HMFFARPEKQ EEVAANVDQF 850 860 870 880 890 900 NDSYARNTTS EELKNVLFLP NWWLRKTSAD CFKTLHQMMK EHRFKGSQCP EGIAKLTERI 910 920 930 940 950 960 QERVHSGYEI PCGWLFKGLT ILFQHRSMDD TGSSGNTVPS DHSYRLRLAI NTARFAGANI 970 980 990 1000 1010 1020 ASSPNQASIT HVVVDPESPS SEISSLRGTW SKKQGQKVPH IVAVDWIEES WKERTLLDEE RFQPKRSKA

References

[1]

"Genomic islands in the pathogenic filamentous fungus Aspergillus fumigatus." Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J., Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H., Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M. , Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J., Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C., White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H., Wortman J.R., Jiang B., Denning D.W., Nierman W.C. PLoS Genet. 4:E1000046-E1000046(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS027049 Genomic DNA. Translation: EAW13069.1.
RefSeq	XP_001274495.1. XM_001274494.1.
3D structure databases
ProteinModelPortal	A1CBF1.
ModBase	Search...
Protein-protein interaction databases
STRING	5057.CADACLAP00001394.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	CADACLAT00001413; CADACLAP00001394; CADACLAG00001413.
GeneID	4706930.
KEGG	act:ACLA_015070.
Phylogenomic databases
HOGENOM	HOG000176213.
KO	K10777.
OrthoDB	EOG41K2MD.
Family and domain databases
Gene3D	2.40.50.140. 1 hit. 3.40.50.10190. 2 hits.
InterPro	IPR001357. BRCT_dom. IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF00533. BRCT. 1 hit. PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view]
SMART	SM00292. BRCT. 1 hit. [Graphical view]
SUPFAM	SSF52113. BRCT. 2 hits. SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS50172. BRCT. 2 hits. PS00697. DNA_LIGASE_A1. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1CBF1_ASPCL

Accession

Primary (citable) accession number: A1CBF1

Entry history

Integrated into UniProtKB/TrEMBL:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	May 29, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)