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A1CBF1

- A1CBF1_ASPCL

UniProt

A1CBF1 - A1CBF1_ASPCL

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Protein

DNA ligase

Gene

ACLA_015070

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:ACLA_015070Imported
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)Imported
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006701: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi5057.CADACLAP00001394.

Structurei

3D structure databases

ProteinModelPortaliA1CBF1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000176213.
KOiK10777.
OMAiHMCPSTK.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1CBF1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNSDDIGPDE GHPRAPVENE ESDLDEKYPN RPRNHSSTLP FHELFQTLFN
60 70 80 90 100
PLSEIKKKPA GAVAARRKVG PHGQSAANLN PLERRRDVIE RFISRWRKEV
110 120 130 140 150
GDDIYPAFRL ILPDKDRDRA MYGIKEKAIG KMLVKIMKID KNSEDGFNLL
160 170 180 190 200
NWKLPGQAAA TRMAGDFAGR CYDVLSKRPM RTDVGDMSIE EVNEKLDNLS
210 220 230 240 250
AASKEEQQLP ILAEFYRRMN PEELMWLIRI ILRQMKVGAT ERTFFDVWHP
260 270 280 290 300
DAENLYSISS SLRRVCWELH DPNIRLDAED RGISLMQCFQ PQLAQFQMQS
310 320 330 340 350
LDKMVSRMRP TEDDPVFWIE EKLDGERMQL HMESDDSVPG GRRFRFWSRK
360 370 380 390 400
AKEYTYLYGN GIYDENGSLT RHLKDAFADG VDSLILDGEM ITWDPEQDAP
410 420 430 440 450
APFGTLKTAA LAEQRNPFST TGARPLFRVF DILYLNGRDL TGYTLRDRRN
460 470 480 490 500
ALQKSVRPVH RRFEIHPYEE ATTKDEVEVA LRKVVAEASE GLVLKNPRSP
510 520 530 540 550
YRLNERHDDW MKVKPEYMTE FGESLDLIVI GGYFGSGRRG GNLSSFLCGL
560 570 580 590 600
RADDTHASQG SNASKCYSFC KVGGGFNAAD YANIRHHTDG KWVEWNPKKP
610 620 630 640 650
PTAYIELAGK DAQYERPDMW IKPEDSVVVC VKAASVSVSD QFRIGLTLRF
660 670 680 690 700
PRFKRLRMDK DWRSALSVQG FLDLKSNVEQ EHREKEFSVD NFRRKRIKRT
710 720 730 740 750
TKKPLAVAGY DADEEAKYAG PSGHIFEGLN FYILTDANAP VKKSKQELEQ
760 770 780 790 800
LVKANGGKFY QTNNAAPHTV CIADRRTVKA ASLQKSGNVD IIRPSWLLDC
810 820 830 840 850
VKQNEIDAGL PDLLLPMEPK HMFFARPEKQ EEVAANVDQF NDSYARNTTS
860 870 880 890 900
EELKNVLFLP NWWLRKTSAD CFKTLHQMMK EHRFKGSQCP EGIAKLTERI
910 920 930 940 950
QERVHSGYEI PCGWLFKGLT ILFQHRSMDD TGSSGNTVPS DHSYRLRLAI
960 970 980 990 1000
NTARFAGANI ASSPNQASIT HVVVDPESPS SEISSLRGTW SKKQGQKVPH
1010 1020
IVAVDWIEES WKERTLLDEE RFQPKRSKA
Length:1,029
Mass (Da):117,611
Last modified:January 23, 2007 - v1
Checksum:i12350CBF4A8E68BA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027049 Genomic DNA. Translation: EAW13069.1.
RefSeqiXP_001274495.1. XM_001274494.1.

Genome annotation databases

EnsemblFungiiCADACLAT00001413; CADACLAP00001394; CADACLAG00001413.
GeneIDi4706930.
KEGGiact:ACLA_015070.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027049 Genomic DNA. Translation: EAW13069.1 .
RefSeqi XP_001274495.1. XM_001274494.1.

3D structure databases

ProteinModelPortali A1CBF1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5057.CADACLAP00001394.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADACLAT00001413 ; CADACLAP00001394 ; CADACLAG00001413 .
GeneIDi 4706930.
KEGGi act:ACLA_015070.

Phylogenomic databases

HOGENOMi HOG000176213.
KOi K10777.
OMAi HMCPSTK.
OrthoDBi EOG7QC84G.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
PANTHERi PTHR10459:SF7. PTHR10459:SF7. 1 hit.
Pfami PF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 1 hit.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1Imported.

Entry informationi

Entry nameiA1CBF1_ASPCL
AccessioniPrimary (citable) accession number: A1CBF1
Entry historyi
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3