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A1CAU3 (XKS1_ASPCL) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable D-xylulose kinase A
Short name=Xylulokinase A
EC=2.7.1.17
Gene names
Name:xkiA
ORF Names:ACLA_012890
OrganismAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) [Complete proteome]
Taxonomic identifier344612 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus ›

Protein attributes

Sequence length573 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway By similarity.

Catalytic activity

ATP + D-xylulose = ADP + D-xylulose 5-phosphate.

Subcellular location

Cytoplasm By similarity.

Induction

By D-xylose, L-arabinose or L-arabitol.

Sequence similarities

Belongs to the FGGY kinase family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Xylose metabolism
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-xylose metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

xylulokinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 573573Probable D-xylulose kinase A
PRO_0000393516

Sequences

Sequence LengthMass (Da)Tools
A1CAU3 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 2248064E535829B4

FASTA57363,148
        10         20         30         40         50         60 
MASQGPLYIG FDLSTQQLKG LVVNSELKVV HISKFDFDAD SRGFSIKKGV LTNEAEHEVF 

        70         80         90        100        110        120 
APVALWLQAL DGVLDGLRKQ GLDFSRVRGI SGAGQQHGSV YWGENAEKLL GGLDAGKTLE 

       130        140        150        160        170        180 
EQLSGAFSHP FSPNWQDAST QKECDEFDAV LGGPEQLAEA TGSKAHHRFT GPQILRFQRK 

       190        200        210        220        230        240 
YPEVYKKTSR ISLVSSFLAS LLLGHIAPMD ISDVCGMNLW NIRKGAYDED LLKLCAGPFG 

       250        260        270        280        290        300 
MEDLKRKLGD VPEDGGLHLG KINKYYIDRY GFSSDCEILP STGDNPATIL ALPLRPSDAM 

       310        320        330        340        350        360 
VSLGTSTTFL MSTPSYKPDP ATHFFNHPTT PGLYMFMLCY KNGGLAREHV RDAINEKLGS 

       370        380        390        400        410        420 
PASQSWENFD RITLETPPLG QKSESDPMKL GLFFPRPEIV PNLRSGQWRF NYNPANETLT 

       430        440        450        460        470        480 
ESNDGWNNPS DEARAIVESQ MLSLRLRSRG LTQSPGAKIP PQPRRVYLVG GGSKNKAIAK 

       490        500        510        520        530        540 
VAGEILGGSD GVYKLDVGDN ACALGAAYKA VWAMERTPGQ TFEDLIGQRW REEEFIEKIA 

       550        560        570 
DGYQKGVFEK YGNAVEGFEK MEHQVLEQEA ARK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		DS027049 Genomic DNA. Translation: EAW12861.1.
RefSeqXP_001274287.1. XM_001274286.1.

3D structure databases

ProteinModelPortalA1CAU3.
ModBaseSearch...

Protein-protein interaction databases

STRING5057.CADACLAP00001387.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADACLAT00001406; CADACLAP00001387; CADACLAG00001406.
GeneID4706424.
KEGGact:ACLA_012890.

Phylogenomic databases

eggNOGCOG1070.
HOGENOMHOG000174850.
KOK00854.
OrthoDBEOG4578GH.

Family and domain databases

InterProIPR018485. Carb_kinase_FGGY_C.
IPR018484. Carb_kinase_FGGY_N.
[Graphical view]
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
PROSITEPS00933. FGGY_KINASES_1. False negative.
PS00445. FGGY_KINASES_2. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameXKS1_ASPCL
AccessionPrimary (citable) accession number: A1CAU3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: January 23, 2007
Last modified: April 3, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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