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A1CAL7

- SHO1_ASPCL

UniProt

A1CAL7 - SHO1_ASPCL

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Protein
High osmolarity signaling protein sho1
Gene
sho1, ACLA_012130
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity By similarity.

GO - Biological processi

  1. response to stress Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
High osmolarity signaling protein sho1
Alternative name(s):
Osmosensor sho1
Gene namesi
Name:sho1
ORF Names:ACLA_012130
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006701: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1414Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei15 – 3521Helical; Reviewed prediction
Add
BLAST
Topological domaini36 – 4611Extracellular Reviewed prediction
Add
BLAST
Transmembranei47 – 6721Helical; Reviewed prediction
Add
BLAST
Topological domaini68 – 692Cytoplasmic Reviewed prediction
Transmembranei70 – 9021Helical; Reviewed prediction
Add
BLAST
Topological domaini91 – 10414Extracellular Reviewed prediction
Add
BLAST
Transmembranei105 – 12521Helical; Reviewed prediction
Add
BLAST
Topological domaini126 – 292167Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 292292High osmolarity signaling protein sho1
PRO_0000410358Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi100 – 1001N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Interactioni

Subunit structurei

Forms homooligomers By similarity.

Protein-protein interaction databases

STRINGi5057.CADACLAP00001234.

Structurei

3D structure databases

ProteinModelPortaliA1CAL7.
SMRiA1CAL7. Positions 234-292.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini233 – 29260SH3
Add
BLAST

Sequence similaritiesi

Belongs to the SHO1 family.
Contains 1 SH3 domain.

Keywords - Domaini

SH3 domain, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000174182.
KOiK11246.
OMAiGSDTIQT.
OrthoDBiEOG7MPRR4.

Family and domain databases

InterProiIPR001452. SH3_domain.
[Graphical view]
PfamiPF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1CAL7-1 [UniParc]FASTAAdd to Basket

« Hide

MARFRASNIL GDPFALATIS IAILAWIIAF ISSIIANIKM ADYPNHAWWA    50
IAYMFCCTIG VTVVVGSDTG LVYGVAVVGY LSAGLVLTSL SVNTLVYKGN 100
SSAQAAAAGF ILLSMIIIVW IFYFGSTPQA THRGFIDSFA LNKEGGNAYG 150
NGRPISTAFG HRPETTSTSA PQMYTSAQLN GFETSSPISG YPGGAPGSEN 200
RSSSQPRFGN PSASNLPANN NGQSQDEVPQ PTEYPYRAKA IYSYDANPED 250
ANEISFSKHE ILEVSDVSGR WWQARKSSGE TGIAPSNYLI LL 292
Length:292
Mass (Da):31,192
Last modified:January 23, 2007 - v1
Checksum:iAD1484F9079AD04A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027049 Genomic DNA. Translation: EAW12785.1.
RefSeqiXP_001274211.1. XM_001274210.1.

Genome annotation databases

EnsemblFungiiCADACLAT00001253; CADACLAP00001234; CADACLAG00001253.
GeneIDi4706489.
KEGGiact:ACLA_012130.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027049 Genomic DNA. Translation: EAW12785.1 .
RefSeqi XP_001274211.1. XM_001274210.1.

3D structure databases

ProteinModelPortali A1CAL7.
SMRi A1CAL7. Positions 234-292.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5057.CADACLAP00001234.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADACLAT00001253 ; CADACLAP00001234 ; CADACLAG00001253 .
GeneIDi 4706489.
KEGGi act:ACLA_012130.

Phylogenomic databases

HOGENOMi HOG000174182.
KOi K11246.
OMAi GSDTIQT.
OrthoDBi EOG7MPRR4.

Family and domain databases

InterProi IPR001452. SH3_domain.
[Graphical view ]
Pfami PF00018. SH3_1. 1 hit.
[Graphical view ]
PRINTSi PR00452. SH3DOMAIN.
SMARTi SM00326. SH3. 1 hit.
[Graphical view ]
SUPFAMi SSF50044. SSF50044. 1 hit.
PROSITEi PS50002. SH3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1.

Entry informationi

Entry nameiSHO1_ASPCL
AccessioniPrimary (citable) accession number: A1CAL7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 28, 2011
Last sequence update: January 23, 2007
Last modified: May 14, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi