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A1CAL7 (SHO1_ASPCL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
High osmolarity signaling protein sho1
Alternative name(s):
Osmosensor sho1
Gene names
Name:sho1
ORF Names:ACLA_012130
OrganismAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) [Complete proteome]
Taxonomic identifier344612 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length292 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity By similarity.

Subunit structure

Forms homooligomers By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the SHO1 family.

Contains 1 SH3 domain.

Ontologies

Keywords
   Biological processStress response
   Cellular componentCell membrane
Membrane
   DomainSH3 domain
Transmembrane
Transmembrane helix
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processresponse to stress

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 292292High osmolarity signaling protein sho1
PRO_0000410358

Regions

Topological domain1 – 1414Cytoplasmic Potential
Transmembrane15 – 3521Helical; Potential
Topological domain36 – 4611Extracellular Potential
Transmembrane47 – 6721Helical; Potential
Topological domain68 – 692Cytoplasmic Potential
Transmembrane70 – 9021Helical; Potential
Topological domain91 – 10414Extracellular Potential
Transmembrane105 – 12521Helical; Potential
Topological domain126 – 292167Cytoplasmic Potential
Domain233 – 29260SH3

Amino acid modifications

Glycosylation1001N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A1CAL7 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: AD1484F9079AD04A

FASTA29231,192
        10         20         30         40         50         60 
MARFRASNIL GDPFALATIS IAILAWIIAF ISSIIANIKM ADYPNHAWWA IAYMFCCTIG 

        70         80         90        100        110        120 
VTVVVGSDTG LVYGVAVVGY LSAGLVLTSL SVNTLVYKGN SSAQAAAAGF ILLSMIIIVW 

       130        140        150        160        170        180 
IFYFGSTPQA THRGFIDSFA LNKEGGNAYG NGRPISTAFG HRPETTSTSA PQMYTSAQLN 

       190        200        210        220        230        240 
GFETSSPISG YPGGAPGSEN RSSSQPRFGN PSASNLPANN NGQSQDEVPQ PTEYPYRAKA 

       250        260        270        280        290 
IYSYDANPED ANEISFSKHE ILEVSDVSGR WWQARKSSGE TGIAPSNYLI LL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS027049 Genomic DNA. Translation: EAW12785.1.
RefSeqXP_001274211.1. XM_001274210.1.

3D structure databases

ProteinModelPortalA1CAL7.
SMRA1CAL7. Positions 234-292.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5057.CADACLAP00001234.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADACLAT00001253; CADACLAP00001234; CADACLAG00001253.
GeneID4706489.
KEGGact:ACLA_012130.

Phylogenomic databases

HOGENOMHOG000174182.
KOK11246.
OMAGSDTIQT.
OrthoDBEOG7MPRR4.

Family and domain databases

InterProIPR001452. SH3_domain.
[Graphical view]
PfamPF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSPR00452. SH3DOMAIN.
SMARTSM00326. SH3. 1 hit.
[Graphical view]
SUPFAMSSF50044. SSF50044. 1 hit.
PROSITEPS50002. SH3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSHO1_ASPCL
AccessionPrimary (citable) accession number: A1CAL7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 28, 2011
Last sequence update: January 23, 2007
Last modified: May 14, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families