Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable glucan endo-1,3-beta-glucosidase btgC

Gene

btgC

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Active on laminarin and lichenan (By similarity).By similarity

Catalytic activityi

Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei597NucleophileBy similarity1
Active sitei665Proton donorBy similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cell wall biogenesis/degradation, Polysaccharide degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glucan endo-1,3-beta-glucosidase btgC (EC:3.2.1.39)
Alternative name(s):
Endo-1,3-beta-glucanase btgC
Laminarinase btgC
Gene namesi
Name:btgC
ORF Names:ACLA_011750
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006701 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:ACLA_011750.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 317CytoplasmicSequence analysisAdd BLAST317
Transmembranei318 – 338Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini339 – 695ExtracellularSequence analysisAdd BLAST357

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003951211 – 695Probable glucan endo-1,3-beta-glucosidase btgCAdd BLAST695

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi415N-linked (GlcNAc...)Sequence analysis1
Glycosylationi438N-linked (GlcNAc...)Sequence analysis1
Glycosylationi466N-linked (GlcNAc...)Sequence analysis1
Glycosylationi642N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliA1CAI0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi264 – 353Gly-richAdd BLAST90

Sequence similaritiesi

Belongs to the glycosyl hydrolase 17 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000173877.
OMAiWLGVWQD.
OrthoDBiEOG092C2Q0O.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

A1CAI0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGPHRTFSF EQRGDGEAHS SFMDHAMHPQ YDDVSPISNM SSSPGHMNET
60 70 80 90 100
HHGLASVPED NHQGWGQARG PSPSNRTGFT ATPEMDNLGP ASVGGGISGI
110 120 130 140 150
ALGVANSHDR LSGVEARRGT DGQEANIPAE RGYNTTGSDN PYIPAPPDMG
160 170 180 190 200
GYGSSETLHP RQSYGSNVAL GAAAGPAGQL TPGHSATHLG TSNSSQRNLY
210 220 230 240 250
DAPYQSAGGL SAGPYQRHSA YSSNDLPLDI NPEEIADDGD DGFAPAGNSR
260 270 280 290 300
SSARRSQAVP AAAGGAAAGG VLGGIGGLFN NRNPAETSYD PVPGAGLEAG
310 320 330 340 350
EKSQWVKPKP STGSRKRGWI IGAILAVIII GAIVGGAVGG TIGHKDSGDS
360 370 380 390 400
ASGSSASTQS ASGDTDTNGD LDKNSAEIKA LMNNKDLHKV FPGMDYTPWG
410 420 430 440 450
VQYPLCLKYP PSQNNVTRDM AVLAQLTNNV RLYGTDCNQT EMVLHAIDKL
460 470 480 490 500
DLKDMKVWLG VWIDTNETTS RRQIDQLYKI VDDAKDISIF NGAIVGNEAL
510 520 530 540 550
FRAGDNKITA QATLTKYMQE VRDHFKKHDI KMPIATSDLG DNWNAELVQI
560 570 580 590 600
ADVVMSNVHP FFGGIPVDQA AAWTWRFWQD HDVILTQGTD KRQVISEVGW
610 620 630 640 650
PSGGGNDCGK GANCPDDTSG AVAGIDELNK FMEDWVCQAL DNGTDYFWFE
660 670 680 690
AFDEPWKIEF NTKNENWEDK WGLMDPARKL KSGLKIPDCG GKTAA
Length:695
Mass (Da):74,031
Last modified:January 23, 2007 - v1
Checksum:iFD2BC27323310650
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027049 Genomic DNA. Translation: EAW12748.1.
RefSeqiXP_001274174.1. XM_001274173.1.

Genome annotation databases

EnsemblFungiiCADACLAT00001237; CADACLAP00001218; CADACLAG00001237.
GeneIDi4706510.
KEGGiact:ACLA_011750.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027049 Genomic DNA. Translation: EAW12748.1.
RefSeqiXP_001274174.1. XM_001274173.1.

3D structure databases

ProteinModelPortaliA1CAI0.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADACLAT00001237; CADACLAP00001218; CADACLAG00001237.
GeneIDi4706510.
KEGGiact:ACLA_011750.

Organism-specific databases

EuPathDBiFungiDB:ACLA_011750.

Phylogenomic databases

HOGENOMiHOG000173877.
OMAiWLGVWQD.
OrthoDBiEOG092C2Q0O.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiBTGC_ASPCL
AccessioniPrimary (citable) accession number: A1CAI0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.