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A1CAI0 (BTGC_ASPCL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable glucan endo-1,3-beta-glucosidase btgC
EC=3.2.1.39
Alternative name(s):
Endo-1,3-beta-glucanase btgC
Laminarinase btgC
Gene names
Name:btgC
ORF Names:ACLA_011750
OrganismAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) [Complete proteome]
Taxonomic identifier344612 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus ›

Protein attributes

Sequence length695 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Glucanases play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation. This enzyme may be involved in beta-glucan degradation. Acive on laminarin and lichenan By similarity.

Catalytic activity

Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.

Subcellular location

Cell membrane; Single-pass type II membrane protein By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 17 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 695695Probable glucan endo-1,3-beta-glucosidase btgC
PRO_0000395121

Regions

Topological domain1 – 317317Cytoplasmic Potential
Transmembrane318 – 33821Helical; Signal-anchor for type II membrane protein; Potential
Topological domain339 – 695357Extracellular Potential
Compositional bias264 – 35390Gly-rich

Sites

Active site5971Nucleophile By similarity
Active site6651Proton donor By similarity

Amino acid modifications

Glycosylation4151N-linked (GlcNAc...) Potential
Glycosylation4381N-linked (GlcNAc...) Potential
Glycosylation4661N-linked (GlcNAc...) Potential
Glycosylation6421N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A1CAI0 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: FD2BC27323310650

FASTA69574,031
        10         20         30         40         50         60 
MSGPHRTFSF EQRGDGEAHS SFMDHAMHPQ YDDVSPISNM SSSPGHMNET HHGLASVPED 

        70         80         90        100        110        120 
NHQGWGQARG PSPSNRTGFT ATPEMDNLGP ASVGGGISGI ALGVANSHDR LSGVEARRGT 

       130        140        150        160        170        180 
DGQEANIPAE RGYNTTGSDN PYIPAPPDMG GYGSSETLHP RQSYGSNVAL GAAAGPAGQL 

       190        200        210        220        230        240 
TPGHSATHLG TSNSSQRNLY DAPYQSAGGL SAGPYQRHSA YSSNDLPLDI NPEEIADDGD 

       250        260        270        280        290        300 
DGFAPAGNSR SSARRSQAVP AAAGGAAAGG VLGGIGGLFN NRNPAETSYD PVPGAGLEAG 

       310        320        330        340        350        360 
EKSQWVKPKP STGSRKRGWI IGAILAVIII GAIVGGAVGG TIGHKDSGDS ASGSSASTQS 

       370        380        390        400        410        420 
ASGDTDTNGD LDKNSAEIKA LMNNKDLHKV FPGMDYTPWG VQYPLCLKYP PSQNNVTRDM 

       430        440        450        460        470        480 
AVLAQLTNNV RLYGTDCNQT EMVLHAIDKL DLKDMKVWLG VWIDTNETTS RRQIDQLYKI 

       490        500        510        520        530        540 
VDDAKDISIF NGAIVGNEAL FRAGDNKITA QATLTKYMQE VRDHFKKHDI KMPIATSDLG 

       550        560        570        580        590        600 
DNWNAELVQI ADVVMSNVHP FFGGIPVDQA AAWTWRFWQD HDVILTQGTD KRQVISEVGW 

       610        620        630        640        650        660 
PSGGGNDCGK GANCPDDTSG AVAGIDELNK FMEDWVCQAL DNGTDYFWFE AFDEPWKIEF 

       670        680        690 
NTKNENWEDK WGLMDPARKL KSGLKIPDCG GKTAA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		DS027049 Genomic DNA. Translation: EAW12748.1.
RefSeqXP_001274174.1. XM_001274173.1.

3D structure databases

ProteinModelPortalA1CAI0.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADACLAT00001237; CADACLAP00001218; CADACLAG00001237.
GeneID4706510.
KEGGact:ACLA_011750.

Phylogenomic databases

eggNOGCOG5309.
HOGENOMHOG000173877.
OrthoDBEOG4KD9WH.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR000490. Glyco_hydro_17.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF00332. Glyco_hydro_17. 1 hit.
[Graphical view]
SUPFAMSSF51445. Glyco_hydro_cat. 1 hit.
PROSITEPS00587. GLYCOSYL_HYDROL_F17. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBTGC_ASPCL
AccessionPrimary (citable) accession number: A1CAI0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: January 23, 2007
Last modified: May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

SIMILARITY comments

Index of protein domains and families

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