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Protein

Probable cutinase 3

Gene

ACLA_055320

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle.By similarity

Catalytic activityi

Cutin + H2O = cutin monomers.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei129 – 1291PROSITE-ProRule annotation
Active sitei184 – 1841PROSITE-ProRule annotation
Active sitei197 – 1971PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Serine esterase

Protein family/group databases

ESTHERiaspcl-cuti3. Cutinase.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cutinase 3 (EC:3.1.1.74)
Alternative name(s):
Cutin hydrolase 3
Gene namesi
ORF Names:ACLA_055320
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006701 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:ACLA_055320.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Sequence analysisAdd
BLAST
Chaini18 – 215198Probable cutinase 3PRO_0000395246Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi39 ↔ 187By similarity
Disulfide bondi118 ↔ 180By similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliA1C9G0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cutinase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000171425.
KOiK08095.
OMAiFGFTRNV.
OrthoDBiEOG092C4OIR.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000675. Cutinase/axe.
IPR011150. Cutinase_monf.
[Graphical view]
PfamiPF01083. Cutinase. 1 hit.
[Graphical view]
PRINTSiPR00129. CUTINASE.
SMARTiSM01110. Cutinase. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00155. CUTINASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A1C9G0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHFRALLVSA LATLAMAAPA PTLEARQSLS SNELENGPCR DVTFIFARGS
60 70 80 90 100
TEQGNMGFIV GPPTCTALKL KLGSDKVACQ GVGGAYTANL LPNFLSQNTD
110 120 130 140 150
PKSIAAATDM FQLARTKCPN TKIVTGGYSQ GSAVIDNSVK ALDDDLKSRV
160 170 180 190 200
KAAVLFGFTR NVVDRGQIPN YPKDQVKVYC AVGDMVCYNT LIITAAHLTY
210
GIYANDAANF LVSKL
Length:215
Mass (Da):22,860
Last modified:January 23, 2007 - v1
Checksum:iFE6B6D44E85E10A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027048 Genomic DNA. Translation: EAW13484.1.
RefSeqiXP_001274910.1. XM_001274909.1.

Genome annotation databases

EnsemblFungiiCADACLAT00005332; CADACLAP00005221; CADACLAG00005332.
GeneIDi4707132.
KEGGiact:ACLA_055320.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027048 Genomic DNA. Translation: EAW13484.1.
RefSeqiXP_001274910.1. XM_001274909.1.

3D structure databases

ProteinModelPortaliA1C9G0.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

ESTHERiaspcl-cuti3. Cutinase.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADACLAT00005332; CADACLAP00005221; CADACLAG00005332.
GeneIDi4707132.
KEGGiact:ACLA_055320.

Organism-specific databases

EuPathDBiFungiDB:ACLA_055320.

Phylogenomic databases

HOGENOMiHOG000171425.
KOiK08095.
OMAiFGFTRNV.
OrthoDBiEOG092C4OIR.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000675. Cutinase/axe.
IPR011150. Cutinase_monf.
[Graphical view]
PfamiPF01083. Cutinase. 1 hit.
[Graphical view]
PRINTSiPR00129. CUTINASE.
SMARTiSM01110. Cutinase. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00155. CUTINASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCUTI3_ASPCL
AccessioniPrimary (citable) accession number: A1C9G0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 13, 2010
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.