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Protein

Xylanolytic transcriptional activator xlnR

Gene

xlnR

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transcriptional activator of the xylanolytic system. Involved in the regulation of extracellular cellulolytic and xylanolytic genes and in the regulation of the intracellular activities of D-xylose catabolic genes in the pentose catabolic pathway (PCP) in response to the presence of D-xylose (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi140 – 16627Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Xylanolytic transcriptional activator xlnR
Alternative name(s):
Xylanase regulator
Gene namesi
Name:xlnR
ORF Names:ACLA_074570
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006701 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:ACLA_074570.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 978978Xylanolytic transcriptional activator xlnRPRO_0000393148Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi5057.CADACLAP00006304.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi81 – 9515His-richAdd
BLAST
Compositional biasi184 – 1929Poly-Ala

Sequence similaritiesi

Belongs to the xlnR/xlr1 family.Curated
Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG132941.
HOGENOMiHOG000167193.
OrthoDBiEOG7380DB.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR007219. Transcription_factor_dom_fun.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF04082. Fungal_trans. 1 hit.
PF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00906. Fungal_trans. 1 hit.
SM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1C7P9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTTSVQHFA PSYPPFSSGL SSNRMAQSQT PGLDTLAEGS QYALEQLQLS
60 70 80 90 100
REAAAGDTTA TAASGPSDPM SKSKDPYDFD HHNHNHHNHH NNNHHPNSNS
110 120 130 140 150
NNSLPGFKNP AQRDPLAEAR SAIRKNSSSA PVRRRISRAC DQCNQLRTRC
160 170 180 190 200
DGQNPCAHCI EFGLTCEYAR ERKKRGKASK KDLAAAAAAA TATPGQPNEN
210 220 230 240 250
PGKDSGTMVG GHSPPDRRQE LNGRYDPAFD AARNLSGSAQ PQLPHAEGPG
260 270 280 290 300
MVGMPNTQHL PSPSQPPMGG GLEGLPMNGY NGLNDSNRPP IPVSELQSLH
310 320 330 340 350
MLHSSNPHPR SPPSILPSQR YNGGYNENAY SLMNPQEHNP TPMNQFRLGN
360 370 380 390 400
STENPPNTFL GLSPPAQSPG WLPLPSPSPA NFPSFSMASF STTLRYPVLH
410 420 430 440 450
PVLPHIASII PQSLACDLLD VYFTSSSSSH LSPQSPYVVG YIFRKQSFLH
460 470 480 490 500
PTKPRACSPG LLASMLWVAA QTSDAPFLTS PPSARGRVCQ KLLELTVGLL
510 520 530 540 550
RPLIHGPAPG ETSPNYAANM VINGIALGGF GVSMDQLGAQ SSATGAVDDV
560 570 580 590 600
ATYVHLATVI SASEYKAASM RWWTAAWSLA RELKLGRELP PNTSQTRQDG
610 620 630 640 650
ERENDPDADP SNRHSPSLIT AMGHGPGNTV INVTEDEREE RRRLWWLLYA
660 670 680 690 700
TDRHLALCYN RPLTLLDKEC NGLLQPMNDD LWQASDFASA SYRQAGPPLE
710 720 730 740 750
CSGHSMFGYF LPLMTILGEI IDLQQARNHP RFGLAFRGSP ECDAQVLEIA
760 770 780 790 800
RQLDLYAQTL KEFETRYTSG LALGAADNDT AMEGSHLNHV SPSGRSSSTV
810 820 830 840 850
DSRVNESIVH TKMVVAYGTH IMHVLHILLA GKWDPINLLD DNDLWISSES
860 870 880 890 900
FIAAMGHAVG AAEAAADILE YDPDLSFMPF FFGIYLLQGS FLLLLTADKL
910 920 930 940 950
QGDASPSVVR ACETIVRAHE ACVVTLNTEY QRTFRKVMRS ALAQVRGRLP
960 970
EDFGEQQQRR REVLALYRWT GDGSGLAL
Length:978
Mass (Da):106,488
Last modified:March 23, 2010 - v2
Checksum:i4EF80E9CCF68E95B
GO

Sequence cautioni

The sequence EAW14420.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027045 Genomic DNA. Translation: EAW14420.1. Different initiation.
RefSeqiXP_001275846.1. XM_001275845.1.

Genome annotation databases

GeneIDi4707549.
KEGGiact:ACLA_074570.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027045 Genomic DNA. Translation: EAW14420.1. Different initiation.
RefSeqiXP_001275846.1. XM_001275845.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5057.CADACLAP00006304.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4707549.
KEGGiact:ACLA_074570.

Organism-specific databases

EuPathDBiFungiDB:ACLA_074570.

Phylogenomic databases

eggNOGiNOG132941.
HOGENOMiHOG000167193.
OrthoDBiEOG7380DB.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR007219. Transcription_factor_dom_fun.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF04082. Fungal_trans. 1 hit.
PF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00906. Fungal_trans. 1 hit.
SM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1.

Entry informationi

Entry nameiXLNR_ASPCL
AccessioniPrimary (citable) accession number: A1C7P9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 23, 2010
Last sequence update: March 23, 2010
Last modified: April 29, 2015
This is version 47 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.