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A1C7E4 (SCONB_ASPCL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable E3 ubiquitin ligase complex SCF subunit sconB
Alternative name(s):
Sulfur controller B
Sulfur metabolite repression control protein B
Gene names
Name:sconB
ORF Names:ACLA_073500
OrganismAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) [Complete proteome]
Taxonomic identifier344612 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length700 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor By similarity.

Pathway

Protein modification; protein ubiquitination.

Subunit structure

Component of the SCF(sconB) E3 ubiquitin ligase complex By similarity.

Sequence similarities

Belongs to the WD repeat MET30/SCONB/SCON-2 family.

Contains 1 F-box domain.

Contains 7 WD repeats.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 700700Probable E3 ubiquitin ligase complex SCF subunit sconB
PRO_0000397245

Regions

Domain195 – 24147F-box
Repeat369 – 40638WD 1
Repeat409 – 44840WD 2
Repeat450 – 48637WD 3
Repeat488 – 52942WD 4
Repeat583 – 62644WD 5
Repeat627 – 66640WD 6
Repeat669 – 70032WD 7

Sequences

Sequence LengthMass (Da)Tools
A1C7E4 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 13AF6C49E352561B

FASTA70078,780
        10         20         30         40         50         60 
MDTQRLSLRK ENGSAHSLLQ DQTGLKENTM NIPRDSSFNS IFGPSEVVDD AGTDRDFKHE 

        70         80         90        100        110        120 
SHKFSITRAM PEKLAGKNIA PFLAKHIPEQ YAPLGSHAGE PVESSGANSR YCYRHRPDLK 

       130        140        150        160        170        180 
CRRQADEPTM DKLQRIAKEL ETLPQRDQQG IAHAWSIFSA APAKHRKLLL QGIMAQCCFP 

       190        200        210        220        230        240 
QLSFISASVR DLIRIDFLTA LPPEISFKIL CYLDTTSLCK AAQVSRRWRA LADDDVVWHR 

       250        260        270        280        290        300 
MCEQHIHRKC KKCGWGLPLL DRKRLRESKR QIELRAATWD ISEQSTEDET GSPAPESASS 

       310        320        330        340        350        360 
NAKRKPESDD EDTALVKRHC TSIVPRLEKE KDGDYFITRY RPWKEVYKDR FKVGTNWKYG 

       370        380        390        400        410        420 
RCSVKVFKGH TNGIMCLQFE DNILATGSYD ATIKIWDTET GEELRTLRGH ESGIRCLQFD 

       430        440        450        460        470        480 
DTKLISGSMD RSLKVWNWRT GECISTYTGH RGGVIGLHFD ATILASASVD KTVKIWNFED 

       490        500        510        520        530        540 
KSTCLLRGHT DWVNAVRVDT NSRTVFSASD DCTIRLWDLD TKTCIRTFHG HVGQVQQVIP 

       550        560        570        580        590        600 
LPREFEFEDH DAECENDNVS VTSGDSPAAS PRGIPGLDAG TSETQSSPFG PAFDNGRPAP 

       610        620        630        640        650        660 
PRYIVTSALD STIRLWETST GRCLRTFFGH LEGVWALAAD TLRIVSGAED RMVKIWDPRT 

       670        680        690        700 
GKCERTFTGH SGPVTCIGLG DSRFATGSED CEVRMYGFQS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS027045 Genomic DNA. Translation: EAW14315.1.
RefSeqXP_001275741.1. XM_001275740.1.

3D structure databases

ProteinModelPortalA1C7E4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5057.CADACLAP00007022.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADACLAT00007182; CADACLAP00007022; CADACLAG00007182.
GeneID4707886.
KEGGact:ACLA_073500.

Phylogenomic databases

eggNOGCOG2319.
HOGENOMHOG000166480.
KOK10259.
OMAMCLQFSE.
OrthoDBEOG7C5MHX.

Enzyme and pathway databases

UniPathwayUPA00143.

Family and domain databases

Gene3D2.130.10.10. 2 hits.
InterProIPR001810. F-box_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamPF00400. WD40. 7 hits.
[Graphical view]
PRINTSPR00320. GPROTEINBRPT.
SMARTSM00256. FBOX. 1 hit.
SM00320. WD40. 7 hits.
[Graphical view]
SUPFAMSSF50978. SSF50978. 2 hits.
SSF81383. SSF81383. 2 hits.
PROSITEPS50181. FBOX. 1 hit.
PS00678. WD_REPEATS_1. 4 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSCONB_ASPCL
AccessionPrimary (citable) accession number: A1C7E4
Entry history
Integrated into UniProtKB/Swiss-Prot: August 10, 2010
Last sequence update: January 23, 2007
Last modified: February 19, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways