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A1C7E4

- SCONB_ASPCL

UniProt

A1C7E4 - SCONB_ASPCL

Protein

Probable E3 ubiquitin ligase complex SCF subunit sconB

Gene

sconB

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.By similarity

    Pathwayi

    GO - Biological processi

    1. protein ubiquitination Source: UniProtKB-UniPathway
    2. regulation of transcription, DNA-templated Source: UniProtKB-KW
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation, Ubl conjugation pathway

    Enzyme and pathway databases

    UniPathwayiUPA00143.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable E3 ubiquitin ligase complex SCF subunit sconB
    Alternative name(s):
    Sulfur controller B
    Sulfur metabolite repression control protein B
    Gene namesi
    Name:sconB
    ORF Names:ACLA_073500
    OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
    Taxonomic identifieri344612 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000006701: Unassembled WGS sequence

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 700700Probable E3 ubiquitin ligase complex SCF subunit sconBPRO_0000397245Add
    BLAST

    Interactioni

    Subunit structurei

    Component of the SCF(sconB) E3 ubiquitin ligase complex.By similarity

    Protein-protein interaction databases

    STRINGi5057.CADACLAP00007022.

    Structurei

    3D structure databases

    ProteinModelPortaliA1C7E4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini195 – 24147F-boxPROSITE-ProRule annotationAdd
    BLAST
    Repeati369 – 40638WD 1Add
    BLAST
    Repeati409 – 44840WD 2Add
    BLAST
    Repeati450 – 48637WD 3Add
    BLAST
    Repeati488 – 52942WD 4Add
    BLAST
    Repeati583 – 62644WD 5Add
    BLAST
    Repeati627 – 66640WD 6Add
    BLAST
    Repeati669 – 70032WD 7Add
    BLAST

    Sequence similaritiesi

    Contains 1 F-box domain.PROSITE-ProRule annotation
    Contains 7 WD repeats.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, WD repeat

    Phylogenomic databases

    eggNOGiCOG2319.
    HOGENOMiHOG000166480.
    KOiK10259.
    OMAiMCLQFSE.
    OrthoDBiEOG7C5MHX.

    Family and domain databases

    Gene3Di2.130.10.10. 2 hits.
    InterProiIPR001810. F-box_dom.
    IPR020472. G-protein_beta_WD-40_rep.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view]
    PfamiPF12937. F-box-like. 1 hit.
    PF00400. WD40. 7 hits.
    [Graphical view]
    PRINTSiPR00320. GPROTEINBRPT.
    SMARTiSM00256. FBOX. 1 hit.
    SM00320. WD40. 7 hits.
    [Graphical view]
    SUPFAMiSSF50978. SSF50978. 2 hits.
    SSF81383. SSF81383. 2 hits.
    PROSITEiPS50181. FBOX. 1 hit.
    PS00678. WD_REPEATS_1. 4 hits.
    PS50082. WD_REPEATS_2. 7 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1C7E4-1 [UniParc]FASTAAdd to Basket

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    MDTQRLSLRK ENGSAHSLLQ DQTGLKENTM NIPRDSSFNS IFGPSEVVDD    50
    AGTDRDFKHE SHKFSITRAM PEKLAGKNIA PFLAKHIPEQ YAPLGSHAGE 100
    PVESSGANSR YCYRHRPDLK CRRQADEPTM DKLQRIAKEL ETLPQRDQQG 150
    IAHAWSIFSA APAKHRKLLL QGIMAQCCFP QLSFISASVR DLIRIDFLTA 200
    LPPEISFKIL CYLDTTSLCK AAQVSRRWRA LADDDVVWHR MCEQHIHRKC 250
    KKCGWGLPLL DRKRLRESKR QIELRAATWD ISEQSTEDET GSPAPESASS 300
    NAKRKPESDD EDTALVKRHC TSIVPRLEKE KDGDYFITRY RPWKEVYKDR 350
    FKVGTNWKYG RCSVKVFKGH TNGIMCLQFE DNILATGSYD ATIKIWDTET 400
    GEELRTLRGH ESGIRCLQFD DTKLISGSMD RSLKVWNWRT GECISTYTGH 450
    RGGVIGLHFD ATILASASVD KTVKIWNFED KSTCLLRGHT DWVNAVRVDT 500
    NSRTVFSASD DCTIRLWDLD TKTCIRTFHG HVGQVQQVIP LPREFEFEDH 550
    DAECENDNVS VTSGDSPAAS PRGIPGLDAG TSETQSSPFG PAFDNGRPAP 600
    PRYIVTSALD STIRLWETST GRCLRTFFGH LEGVWALAAD TLRIVSGAED 650
    RMVKIWDPRT GKCERTFTGH SGPVTCIGLG DSRFATGSED CEVRMYGFQS 700
    Length:700
    Mass (Da):78,780
    Last modified:January 23, 2007 - v1
    Checksum:i13AF6C49E352561B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027045 Genomic DNA. Translation: EAW14315.1.
    RefSeqiXP_001275741.1. XM_001275740.1.

    Genome annotation databases

    EnsemblFungiiCADACLAT00007182; CADACLAP00007022; CADACLAG00007182.
    GeneIDi4707886.
    KEGGiact:ACLA_073500.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027045 Genomic DNA. Translation: EAW14315.1 .
    RefSeqi XP_001275741.1. XM_001275740.1.

    3D structure databases

    ProteinModelPortali A1C7E4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5057.CADACLAP00007022.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADACLAT00007182 ; CADACLAP00007022 ; CADACLAG00007182 .
    GeneIDi 4707886.
    KEGGi act:ACLA_073500.

    Phylogenomic databases

    eggNOGi COG2319.
    HOGENOMi HOG000166480.
    KOi K10259.
    OMAi MCLQFSE.
    OrthoDBi EOG7C5MHX.

    Enzyme and pathway databases

    UniPathwayi UPA00143 .

    Family and domain databases

    Gene3Di 2.130.10.10. 2 hits.
    InterProi IPR001810. F-box_dom.
    IPR020472. G-protein_beta_WD-40_rep.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view ]
    Pfami PF12937. F-box-like. 1 hit.
    PF00400. WD40. 7 hits.
    [Graphical view ]
    PRINTSi PR00320. GPROTEINBRPT.
    SMARTi SM00256. FBOX. 1 hit.
    SM00320. WD40. 7 hits.
    [Graphical view ]
    SUPFAMi SSF50978. SSF50978. 2 hits.
    SSF81383. SSF81383. 2 hits.
    PROSITEi PS50181. FBOX. 1 hit.
    PS00678. WD_REPEATS_1. 4 hits.
    PS50082. WD_REPEATS_2. 7 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1.

    Entry informationi

    Entry nameiSCONB_ASPCL
    AccessioniPrimary (citable) accession number: A1C7E4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 10, 2010
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3