Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable E3 ubiquitin ligase complex SCF subunit sconB

Gene

sconB

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.By similarity

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulation, Ubl conjugation pathway

Enzyme and pathway databases

UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Recommended name:
Probable E3 ubiquitin ligase complex SCF subunit sconB
Alternative name(s):
Sulfur controller B
Sulfur metabolite repression control protein B
Gene namesi
Name:sconB
ORF Names:ACLA_073500
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006701 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:ACLA_073500

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003972451 – 700Probable E3 ubiquitin ligase complex SCF subunit sconBAdd BLAST700

Interactioni

Subunit structurei

Component of the SCF(sconB) E3 ubiquitin ligase complex.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi5057.CADACLAP00007022

Structurei

3D structure databases

ProteinModelPortaliA1C7E4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini195 – 241F-boxPROSITE-ProRule annotationAdd BLAST47
Repeati369 – 406WD 1Add BLAST38
Repeati409 – 448WD 2Add BLAST40
Repeati450 – 486WD 3Add BLAST37
Repeati488 – 529WD 4Add BLAST42
Repeati583 – 626WD 5Add BLAST44
Repeati627 – 666WD 6Add BLAST40
Repeati669 – 700WD 7Add BLAST32

Sequence similaritiesi

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

HOGENOMiHOG000166480
KOiK10259
OMAiTQCCFPQ
OrthoDBiEOG092C10HM

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR036047 F-box-like_dom_sf
IPR001810 F-box_dom
IPR020472 G-protein_beta_WD-40_rep
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF12937 F-box-like, 1 hit
PF00400 WD40, 6 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00256 FBOX, 1 hit
SM00320 WD40, 7 hits
SUPFAMiSSF50978 SSF50978, 2 hits
SSF81383 SSF81383, 2 hits
PROSITEiView protein in PROSITE
PS50181 FBOX, 1 hit
PS00678 WD_REPEATS_1, 4 hits
PS50082 WD_REPEATS_2, 7 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

A1C7E4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTQRLSLRK ENGSAHSLLQ DQTGLKENTM NIPRDSSFNS IFGPSEVVDD
60 70 80 90 100
AGTDRDFKHE SHKFSITRAM PEKLAGKNIA PFLAKHIPEQ YAPLGSHAGE
110 120 130 140 150
PVESSGANSR YCYRHRPDLK CRRQADEPTM DKLQRIAKEL ETLPQRDQQG
160 170 180 190 200
IAHAWSIFSA APAKHRKLLL QGIMAQCCFP QLSFISASVR DLIRIDFLTA
210 220 230 240 250
LPPEISFKIL CYLDTTSLCK AAQVSRRWRA LADDDVVWHR MCEQHIHRKC
260 270 280 290 300
KKCGWGLPLL DRKRLRESKR QIELRAATWD ISEQSTEDET GSPAPESASS
310 320 330 340 350
NAKRKPESDD EDTALVKRHC TSIVPRLEKE KDGDYFITRY RPWKEVYKDR
360 370 380 390 400
FKVGTNWKYG RCSVKVFKGH TNGIMCLQFE DNILATGSYD ATIKIWDTET
410 420 430 440 450
GEELRTLRGH ESGIRCLQFD DTKLISGSMD RSLKVWNWRT GECISTYTGH
460 470 480 490 500
RGGVIGLHFD ATILASASVD KTVKIWNFED KSTCLLRGHT DWVNAVRVDT
510 520 530 540 550
NSRTVFSASD DCTIRLWDLD TKTCIRTFHG HVGQVQQVIP LPREFEFEDH
560 570 580 590 600
DAECENDNVS VTSGDSPAAS PRGIPGLDAG TSETQSSPFG PAFDNGRPAP
610 620 630 640 650
PRYIVTSALD STIRLWETST GRCLRTFFGH LEGVWALAAD TLRIVSGAED
660 670 680 690 700
RMVKIWDPRT GKCERTFTGH SGPVTCIGLG DSRFATGSED CEVRMYGFQS
Length:700
Mass (Da):78,780
Last modified:January 23, 2007 - v1
Checksum:i13AF6C49E352561B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027045 Genomic DNA Translation: EAW14315.1
RefSeqiXP_001275741.1, XM_001275740.1

Genome annotation databases

EnsemblFungiiCADACLAT00007182; CADACLAP00007022; CADACLAG00007182
GeneIDi4707886
KEGGiact:ACLA_073500

Similar proteinsi

Entry informationi

Entry nameiSCONB_ASPCL
AccessioniPrimary (citable) accession number: A1C7E4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 10, 2010
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health