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A1C7E4

- SCONB_ASPCL

UniProt

A1C7E4 - SCONB_ASPCL

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Protein
Probable E3 ubiquitin ligase complex SCF subunit sconB
Gene
sconB, ACLA_073500
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor By similarity.

Pathwayi

GO - Biological processi

  1. protein ubiquitination Source: UniProtKB-UniPathway
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation, Ubl conjugation pathway

Enzyme and pathway databases

UniPathwayiUPA00143.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable E3 ubiquitin ligase complex SCF subunit sconB
Alternative name(s):
Sulfur controller B
Sulfur metabolite repression control protein B
Gene namesi
Name:sconB
ORF Names:ACLA_073500
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006701: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 700700Probable E3 ubiquitin ligase complex SCF subunit sconB
PRO_0000397245Add
BLAST

Interactioni

Subunit structurei

Component of the SCF(sconB) E3 ubiquitin ligase complex By similarity.

Protein-protein interaction databases

STRINGi5057.CADACLAP00007022.

Structurei

3D structure databases

ProteinModelPortaliA1C7E4.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini195 – 24147F-box
Add
BLAST
Repeati369 – 40638WD 1
Add
BLAST
Repeati409 – 44840WD 2
Add
BLAST
Repeati450 – 48637WD 3
Add
BLAST
Repeati488 – 52942WD 4
Add
BLAST
Repeati583 – 62644WD 5
Add
BLAST
Repeati627 – 66640WD 6
Add
BLAST
Repeati669 – 70032WD 7
Add
BLAST

Sequence similaritiesi

Contains 1 F-box domain.
Contains 7 WD repeats.

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiCOG2319.
HOGENOMiHOG000166480.
KOiK10259.
OMAiMCLQFSE.
OrthoDBiEOG7C5MHX.

Family and domain databases

Gene3Di2.130.10.10. 2 hits.
InterProiIPR001810. F-box_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF12937. F-box-like. 1 hit.
PF00400. WD40. 7 hits.
[Graphical view]
PRINTSiPR00320. GPROTEINBRPT.
SMARTiSM00256. FBOX. 1 hit.
SM00320. WD40. 7 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 2 hits.
SSF81383. SSF81383. 2 hits.
PROSITEiPS50181. FBOX. 1 hit.
PS00678. WD_REPEATS_1. 4 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1C7E4-1 [UniParc]FASTAAdd to Basket

« Hide

MDTQRLSLRK ENGSAHSLLQ DQTGLKENTM NIPRDSSFNS IFGPSEVVDD    50
AGTDRDFKHE SHKFSITRAM PEKLAGKNIA PFLAKHIPEQ YAPLGSHAGE 100
PVESSGANSR YCYRHRPDLK CRRQADEPTM DKLQRIAKEL ETLPQRDQQG 150
IAHAWSIFSA APAKHRKLLL QGIMAQCCFP QLSFISASVR DLIRIDFLTA 200
LPPEISFKIL CYLDTTSLCK AAQVSRRWRA LADDDVVWHR MCEQHIHRKC 250
KKCGWGLPLL DRKRLRESKR QIELRAATWD ISEQSTEDET GSPAPESASS 300
NAKRKPESDD EDTALVKRHC TSIVPRLEKE KDGDYFITRY RPWKEVYKDR 350
FKVGTNWKYG RCSVKVFKGH TNGIMCLQFE DNILATGSYD ATIKIWDTET 400
GEELRTLRGH ESGIRCLQFD DTKLISGSMD RSLKVWNWRT GECISTYTGH 450
RGGVIGLHFD ATILASASVD KTVKIWNFED KSTCLLRGHT DWVNAVRVDT 500
NSRTVFSASD DCTIRLWDLD TKTCIRTFHG HVGQVQQVIP LPREFEFEDH 550
DAECENDNVS VTSGDSPAAS PRGIPGLDAG TSETQSSPFG PAFDNGRPAP 600
PRYIVTSALD STIRLWETST GRCLRTFFGH LEGVWALAAD TLRIVSGAED 650
RMVKIWDPRT GKCERTFTGH SGPVTCIGLG DSRFATGSED CEVRMYGFQS 700
Length:700
Mass (Da):78,780
Last modified:January 23, 2007 - v1
Checksum:i13AF6C49E352561B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027045 Genomic DNA. Translation: EAW14315.1.
RefSeqiXP_001275741.1. XM_001275740.1.

Genome annotation databases

EnsemblFungiiCADACLAT00007182; CADACLAP00007022; CADACLAG00007182.
GeneIDi4707886.
KEGGiact:ACLA_073500.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027045 Genomic DNA. Translation: EAW14315.1 .
RefSeqi XP_001275741.1. XM_001275740.1.

3D structure databases

ProteinModelPortali A1C7E4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5057.CADACLAP00007022.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADACLAT00007182 ; CADACLAP00007022 ; CADACLAG00007182 .
GeneIDi 4707886.
KEGGi act:ACLA_073500.

Phylogenomic databases

eggNOGi COG2319.
HOGENOMi HOG000166480.
KOi K10259.
OMAi MCLQFSE.
OrthoDBi EOG7C5MHX.

Enzyme and pathway databases

UniPathwayi UPA00143 .

Family and domain databases

Gene3Di 2.130.10.10. 2 hits.
InterProi IPR001810. F-box_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view ]
Pfami PF12937. F-box-like. 1 hit.
PF00400. WD40. 7 hits.
[Graphical view ]
PRINTSi PR00320. GPROTEINBRPT.
SMARTi SM00256. FBOX. 1 hit.
SM00320. WD40. 7 hits.
[Graphical view ]
SUPFAMi SSF50978. SSF50978. 2 hits.
SSF81383. SSF81383. 2 hits.
PROSITEi PS50181. FBOX. 1 hit.
PS00678. WD_REPEATS_1. 4 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1.

Entry informationi

Entry nameiSCONB_ASPCL
AccessioniPrimary (citable) accession number: A1C7E4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 10, 2010
Last sequence update: January 23, 2007
Last modified: June 11, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi