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A1C7B5 (EGLX_ASPCL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable endo-1,3(4)-beta-glucanase ACLA_073210

EC=3.2.1.6
Alternative name(s):
Mixed-linked glucanase ACLA_073210
Gene names
ORF Names:ACLA_073210
OrganismAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) [Complete proteome]
Taxonomic identifier344612 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length639 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Mixed-linked glucanase involved in the degradation of complex natural cellulosic substrates By similarity.

Catalytic activity

Endohydrolysis of (1->3)- or (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolyzed is itself substituted at C-3.

Subcellular location

Cell membrane; Lipid-anchorGPI-anchor By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 16 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2121 Potential
Chain22 – 617596Probable endo-1,3(4)-beta-glucanase ACLA_073210
PRO_0000395082
Propeptide618 – 63922Removed in mature form Potential
PRO_0000395083

Regions

Compositional bias357 – 43680Thr-rich

Sites

Active site1461Nucleophile By similarity
Active site1511Proton donor By similarity

Amino acid modifications

Lipidation6171GPI-anchor amidated alanine Potential
Glycosylation651N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A1C7B5 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 5CF35BA52DF084C0

FASTA63965,108
        10         20         30         40         50         60 
MAPSSLLLSV GSLIASSLAS ATSLQIREQS QSYQLTESWQ GESFINDWNF FDRGDPTNGY 

        70         80         90        100        110        120 
VTYVNQSVAE SSGLVKVTQS GSFYMGVDYE SKLNPDGPGR ESVRIESKKY YTQGLYVVDI 

       130        140        150        160        170        180 
AHMPGSICGT WPAFWSVGAN WPHDGEIDII EGVNKHDANE IVLHTSGSCD VAGSHDMTGS 

       190        200        210        220        230        240 
LTSGECGDAS GTIGCVVKGT QGSAGDPFNA QGGGVYAIEW TDSFLKIWFF PRNSIPASIT 

       250        260        270        280        290        300 
AGKPDSSAFG TPMAHLQGTC DFAERFKEQK FILDTTFCGD WAGNVFGESG CPLSDASSPM 

       310        320        330        340        350        360 
RSCVDYVAQN PAAFKEAYWE INSIKIYQLG AAPAPATVAS PNTASEVHSA SELAPATQTE 

       370        380        390        400        410        420 
KPTVPTAAET TVVPPASQTS TVAEETPIAP LATAATVTAV NPAPPATQPT AEPATAVTVT 

       430        440        450        460        470        480 
DGGDSFRTIF LTSTTTICPE AQSSSSAAAH GGNKNAPVGA VPGQPSGADA VGNPNPSTTT 

       490        500        510        520        530        540 
EAVAETETSQ PELTAGGISE LPKSAPAPTA SQPTSEFKPS DVPDVPKPSP EAEHPAPPAA 

       550        560        570        580        590        600 
AGSSIINTPS SSAIFGSSTA VGTFTSLARV SRPTGGATFV PTIATATGSP TVGEDGSSGS 

       610        620        630 
ATASATLTAP TGILFTAGAR KLSVGLSGLV GALAVAALA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS027045 Genomic DNA. Translation: EAW14286.1.
RefSeqXP_001275712.1. XM_001275711.1.

3D structure databases

ProteinModelPortalA1C7B5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADACLAT00006512; CADACLAP00006352; CADACLAG00006512.
GeneID4708021.
KEGGact:ACLA_073210.

Phylogenomic databases

eggNOGNOG12793.
HOGENOMHOG000166269.
OMAIESKKYY.
OrthoDBEOG7HB5KN.

Family and domain databases

Gene3D2.60.120.200. 2 hits.
InterProIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR000757. Glyco_hydro_16.
[Graphical view]
PfamPF00722. Glyco_hydro_16. 1 hit.
[Graphical view]
SUPFAMSSF49899. SSF49899. 2 hits.
ProtoNetSearch...

Entry information

Entry nameEGLX_ASPCL
AccessionPrimary (citable) accession number: A1C7B5
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: January 23, 2007
Last modified: February 19, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries