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A1C603

- RIFK_ASPCL

UniProt

A1C603 - RIFK_ASPCL

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Protein

Riboflavin kinase

Gene
fmn1, ACLA_068520
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme By similarity.

Catalytic activityi

ATP + riboflavin = ADP + FMN.

Cofactori

Zinc or magnesium By similarity.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi44 – 441Magnesium or zinc By similarity
Active sitei112 – 1121Nucleophile By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. riboflavin kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. FMN biosynthetic process Source: UniProtKB-UniPathway
  2. riboflavin biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Flavoprotein, FMN, Magnesium, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

UniPathwayiUPA00276; UER00406.

Names & Taxonomyi

Protein namesi
Recommended name:
Riboflavin kinase (EC:2.7.1.26)
Alternative name(s):
Flavin mononucleotide kinase 1
Gene namesi
Name:fmn1
ORF Names:ACLA_068520
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006701: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 214214Riboflavin kinasePRO_0000301833Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi5057.CADACLAP00006243.

Structurei

3D structure databases

ProteinModelPortaliA1C603.

Family & Domainsi

Sequence similaritiesi

Belongs to the flavokinase family.

Phylogenomic databases

eggNOGiCOG0196.
HOGENOMiHOG000260803.
KOiK00861.
OMAiINFDCEV.
OrthoDBiEOG7K3V05.

Family and domain databases

Gene3Di2.40.30.30. 1 hit.
InterProiIPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view]
PANTHERiPTHR22749. PTHR22749. 1 hit.
PfamiPF01687. Flavokinase. 1 hit.
[Graphical view]
SMARTiSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMiSSF82114. SSF82114. 1 hit.

Sequencei

Sequence statusi: Complete.

A1C603-1 [UniParc]FASTAAdd to Basket

« Hide

MRPDGPRDPV VGPDSGPEPP YPVRLSGPVI KGFGRGSKEL GIPTANIPAE    50
ELAEHPDLQV GVYYGVVALD PAKFQYHGDA SRKGEDSQAA ILPAVLSIGY 100
NPFYKNKTRS IEIHIMPPLS SPSPTAEVTT QGQGHGQVKF HKLPDFYGTQ 150
LKLLILGYIR PEFDYVSLEA LVEDIRVDCE VARASLQRPA YERYLAGGQG 200
LDAVEKQRRW LVSF 214
Length:214
Mass (Da):23,496
Last modified:January 23, 2007 - v1
Checksum:i4879EFA4E1FAC669
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027045 Genomic DNA. Translation: EAW13824.1.
RefSeqiXP_001275250.1. XM_001275249.1.

Genome annotation databases

EnsemblFungiiCADACLAT00006403; CADACLAP00006243; CADACLAG00006403.
GeneIDi4707980.
KEGGiact:ACLA_068520.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027045 Genomic DNA. Translation: EAW13824.1 .
RefSeqi XP_001275250.1. XM_001275249.1.

3D structure databases

ProteinModelPortali A1C603.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5057.CADACLAP00006243.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADACLAT00006403 ; CADACLAP00006243 ; CADACLAG00006403 .
GeneIDi 4707980.
KEGGi act:ACLA_068520.

Phylogenomic databases

eggNOGi COG0196.
HOGENOMi HOG000260803.
KOi K00861.
OMAi INFDCEV.
OrthoDBi EOG7K3V05.

Enzyme and pathway databases

UniPathwayi UPA00276 ; UER00406 .

Family and domain databases

Gene3Di 2.40.30.30. 1 hit.
InterProi IPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view ]
PANTHERi PTHR22749. PTHR22749. 1 hit.
Pfami PF01687. Flavokinase. 1 hit.
[Graphical view ]
SMARTi SM00904. Flavokinase. 1 hit.
[Graphical view ]
SUPFAMi SSF82114. SSF82114. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1.

Entry informationi

Entry nameiRIFK_ASPCL
AccessioniPrimary (citable) accession number: A1C603
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: January 23, 2007
Last modified: May 14, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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