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A1C603

- RIFK_ASPCL

UniProt

A1C603 - RIFK_ASPCL

Protein

Riboflavin kinase

Gene

fmn1

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.By similarity

    Catalytic activityi

    ATP + riboflavin = ADP + FMN.

    Cofactori

    Zinc or magnesium.By similarity

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi44 – 441Magnesium or zincBy similarity
    Active sitei112 – 1121NucleophileBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-KW
    3. riboflavin kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. FMN biosynthetic process Source: UniProtKB-UniPathway
    2. riboflavin biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Flavoprotein, FMN, Magnesium, Metal-binding, Nucleotide-binding, Zinc

    Enzyme and pathway databases

    UniPathwayiUPA00276; UER00406.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Riboflavin kinase (EC:2.7.1.26)
    Alternative name(s):
    Flavin mononucleotide kinase 1
    Gene namesi
    Name:fmn1
    ORF Names:ACLA_068520
    OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
    Taxonomic identifieri344612 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000006701: Unassembled WGS sequence

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 214214Riboflavin kinasePRO_0000301833Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi5057.CADACLAP00006243.

    Structurei

    3D structure databases

    ProteinModelPortaliA1C603.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the flavokinase family.Curated

    Phylogenomic databases

    eggNOGiCOG0196.
    HOGENOMiHOG000260803.
    KOiK00861.
    OMAiINFDCEV.
    OrthoDBiEOG7K3V05.

    Family and domain databases

    Gene3Di2.40.30.30. 1 hit.
    InterProiIPR023468. Riboflavin_kinase.
    IPR015865. Riboflavin_kinase_bac/euk.
    IPR023465. Riboflavin_kinase_domain.
    [Graphical view]
    PANTHERiPTHR22749. PTHR22749. 1 hit.
    PfamiPF01687. Flavokinase. 1 hit.
    [Graphical view]
    SMARTiSM00904. Flavokinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF82114. SSF82114. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A1C603-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRPDGPRDPV VGPDSGPEPP YPVRLSGPVI KGFGRGSKEL GIPTANIPAE    50
    ELAEHPDLQV GVYYGVVALD PAKFQYHGDA SRKGEDSQAA ILPAVLSIGY 100
    NPFYKNKTRS IEIHIMPPLS SPSPTAEVTT QGQGHGQVKF HKLPDFYGTQ 150
    LKLLILGYIR PEFDYVSLEA LVEDIRVDCE VARASLQRPA YERYLAGGQG 200
    LDAVEKQRRW LVSF 214
    Length:214
    Mass (Da):23,496
    Last modified:January 23, 2007 - v1
    Checksum:i4879EFA4E1FAC669
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027045 Genomic DNA. Translation: EAW13824.1.
    RefSeqiXP_001275250.1. XM_001275249.1.

    Genome annotation databases

    EnsemblFungiiCADACLAT00006403; CADACLAP00006243; CADACLAG00006403.
    GeneIDi4707980.
    KEGGiact:ACLA_068520.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS027045 Genomic DNA. Translation: EAW13824.1 .
    RefSeqi XP_001275250.1. XM_001275249.1.

    3D structure databases

    ProteinModelPortali A1C603.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5057.CADACLAP00006243.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADACLAT00006403 ; CADACLAP00006243 ; CADACLAG00006403 .
    GeneIDi 4707980.
    KEGGi act:ACLA_068520.

    Phylogenomic databases

    eggNOGi COG0196.
    HOGENOMi HOG000260803.
    KOi K00861.
    OMAi INFDCEV.
    OrthoDBi EOG7K3V05.

    Enzyme and pathway databases

    UniPathwayi UPA00276 ; UER00406 .

    Family and domain databases

    Gene3Di 2.40.30.30. 1 hit.
    InterProi IPR023468. Riboflavin_kinase.
    IPR015865. Riboflavin_kinase_bac/euk.
    IPR023465. Riboflavin_kinase_domain.
    [Graphical view ]
    PANTHERi PTHR22749. PTHR22749. 1 hit.
    Pfami PF01687. Flavokinase. 1 hit.
    [Graphical view ]
    SMARTi SM00904. Flavokinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF82114. SSF82114. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1.

    Entry informationi

    Entry nameiRIFK_ASPCL
    AccessioniPrimary (citable) accession number: A1C603
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3