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A1C603

- RIFK_ASPCL

UniProt

A1C603 - RIFK_ASPCL

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Protein

Riboflavin kinase

Gene

fmn1

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.By similarity

Catalytic activityi

ATP + riboflavin = ADP + FMN.

Cofactori

Zinc or magnesium.By similarity

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi44 – 441Magnesium or zincBy similarity
Active sitei112 – 1121NucleophileBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. riboflavin kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. FMN biosynthetic process Source: UniProtKB-UniPathway
  2. riboflavin biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Flavoprotein, FMN, Magnesium, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

UniPathwayiUPA00276; UER00406.

Names & Taxonomyi

Protein namesi
Recommended name:
Riboflavin kinase (EC:2.7.1.26)
Alternative name(s):
Flavin mononucleotide kinase 1
Gene namesi
Name:fmn1
ORF Names:ACLA_068520
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006701: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 214214Riboflavin kinasePRO_0000301833Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi5057.CADACLAP00006243.

Structurei

3D structure databases

ProteinModelPortaliA1C603.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the flavokinase family.Curated

Phylogenomic databases

eggNOGiCOG0196.
HOGENOMiHOG000260803.
KOiK00861.
OMAiINFDCEV.
OrthoDBiEOG7K3V05.

Family and domain databases

Gene3Di2.40.30.30. 1 hit.
InterProiIPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view]
PANTHERiPTHR22749. PTHR22749. 1 hit.
PfamiPF01687. Flavokinase. 1 hit.
[Graphical view]
SMARTiSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMiSSF82114. SSF82114. 1 hit.

Sequencei

Sequence statusi: Complete.

A1C603-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRPDGPRDPV VGPDSGPEPP YPVRLSGPVI KGFGRGSKEL GIPTANIPAE
60 70 80 90 100
ELAEHPDLQV GVYYGVVALD PAKFQYHGDA SRKGEDSQAA ILPAVLSIGY
110 120 130 140 150
NPFYKNKTRS IEIHIMPPLS SPSPTAEVTT QGQGHGQVKF HKLPDFYGTQ
160 170 180 190 200
LKLLILGYIR PEFDYVSLEA LVEDIRVDCE VARASLQRPA YERYLAGGQG
210
LDAVEKQRRW LVSF
Length:214
Mass (Da):23,496
Last modified:January 23, 2007 - v1
Checksum:i4879EFA4E1FAC669
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027045 Genomic DNA. Translation: EAW13824.1.
RefSeqiXP_001275250.1. XM_001275249.1.

Genome annotation databases

EnsemblFungiiCADACLAT00006403; CADACLAP00006243; CADACLAG00006403.
GeneIDi4707980.
KEGGiact:ACLA_068520.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027045 Genomic DNA. Translation: EAW13824.1 .
RefSeqi XP_001275250.1. XM_001275249.1.

3D structure databases

ProteinModelPortali A1C603.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5057.CADACLAP00006243.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADACLAT00006403 ; CADACLAP00006243 ; CADACLAG00006403 .
GeneIDi 4707980.
KEGGi act:ACLA_068520.

Phylogenomic databases

eggNOGi COG0196.
HOGENOMi HOG000260803.
KOi K00861.
OMAi INFDCEV.
OrthoDBi EOG7K3V05.

Enzyme and pathway databases

UniPathwayi UPA00276 ; UER00406 .

Family and domain databases

Gene3Di 2.40.30.30. 1 hit.
InterProi IPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view ]
PANTHERi PTHR22749. PTHR22749. 1 hit.
Pfami PF01687. Flavokinase. 1 hit.
[Graphical view ]
SMARTi SM00904. Flavokinase. 1 hit.
[Graphical view ]
SUPFAMi SSF82114. SSF82114. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1.

Entry informationi

Entry nameiRIFK_ASPCL
AccessioniPrimary (citable) accession number: A1C603
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: January 23, 2007
Last modified: October 1, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3