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A1C602

- ACUK_ASPCL

UniProt

A1C602 - ACUK_ASPCL

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Protein

Transcription activator of gluconeogenesis acuK

Gene

acuK

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi69 – 9729Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: InterPro
  3. zinc ion binding Source: InterPro

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Gluconeogenesis, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription activator of gluconeogenesis acuK
Gene namesi
Name:acuK
ORF Names:AN7468
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006701: Unassembled WGS sequence

Subcellular locationi

Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 698698Transcription activator of gluconeogenesis acuKPRO_0000406430Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi5057.CADACLAP00006444.

Structurei

3D structure databases

ProteinModelPortaliA1C602.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ERT1/acuK family.Curated
Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG39365.
HOGENOMiHOG000162694.
OMAiLGHMSSG.
OrthoDBiEOG70KGZB.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1C602-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNVEAKESSV APAGDHGGAV QDPADVRDRL ELLKNKANGE TNGATPNGTK
60 70 80 90 100
STNAKDPSRP RRKKARRACF ACQRAHLTCG DERPCQRCIK RGLQDACHDG
110 120 130 140 150
VRKKAKYLHD APDGALMPGV GGNFYNHPMR HNMPLSSNGA NAVNATSQQN
160 170 180 190 200
SGASFYPTPQ SNPYNVYQES TLSQNSFPSQ SPVSPTFNMK NTATARSNSL
210 220 230 240 250
SSSVNQPQSN PAASGPPSQS QNPFAGPFFD PSDPALFNFD LSSMNFENRY
260 270 280 290 300
GALEFGMLGH MATGAGDSPS ESATQRGSIG RSGSAQFATT PITGNPGFGE
310 320 330 340 350
SPGNQQPFMF GNDPLLNEWP NNHPPGQGHM NVGGVYPQNS MMAGHLSKAD
360 370 380 390 400
APHAFAIESG PASFSSPSAT TSPHVNGGYD ENALSNAVAH KPNGLPTNGQ
410 420 430 440 450
RPAITTPRLK HQSLQLGVKR RHRNPSTVYE SVKEPYAYTN RFHNLTAFIQ
460 470 480 490 500
RRFSSQKTLQ IAKALASIRP SFIATTKTLN RDDLIFMEKC FQRTLWEYED
510 520 530 540 550
FINACGTPTI VCRRTGEIAA VGKEFSILTG WKKDVLLGKE PNLNVNTGGT
560 570 580 590 600
SIPQSGTSSR GSFTPRISTL EQANPARPQP VFLAELLDDD SVVDFYEDFA
610 620 630 640 650
RLAFGDSRGS VMTTCKLLKY KTKEDMELAQ SDDNQRWNNH LRKGGIAGEA
660 670 680 690
GMNQLGFKDG KVECAYCWTV KRDVFDIPML IVMNYLIPSD GFKSSIPF
Length:698
Mass (Da):75,805
Last modified:January 23, 2007 - v1
Checksum:i1AEE9421BEAC6485
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027045 Genomic DNA. Translation: EAW13823.1.
RefSeqiXP_001275249.1. XM_001275248.1.

Genome annotation databases

EnsemblFungiiCADACLAT00006604; CADACLAP00006444; CADACLAG00006604.
GeneIDi4707944.
KEGGiact:ACLA_068510.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS027045 Genomic DNA. Translation: EAW13823.1 .
RefSeqi XP_001275249.1. XM_001275248.1.

3D structure databases

ProteinModelPortali A1C602.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5057.CADACLAP00006444.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADACLAT00006604 ; CADACLAP00006444 ; CADACLAG00006604 .
GeneIDi 4707944.
KEGGi act:ACLA_068510.

Phylogenomic databases

eggNOGi NOG39365.
HOGENOMi HOG000162694.
OMAi LGHMSSG.
OrthoDBi EOG70KGZB.

Family and domain databases

Gene3Di 4.10.240.10. 1 hit.
InterProi IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view ]
SMARTi SM00066. GAL4. 1 hit.
[Graphical view ]
SUPFAMi SSF57701. SSF57701. 1 hit.
PROSITEi PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1.

Entry informationi

Entry nameiACUK_ASPCL
AccessioniPrimary (citable) accession number: A1C602
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3