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Protein

Glutamate decarboxylase

Gene

ACLA_059420

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:ACLA_059420Imported
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)Imported
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006701 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:ACLA_059420.

Interactioni

Protein-protein interaction databases

STRINGi5057.CADACLAP00005332.

Structurei

3D structure databases

ProteinModelPortaliA1C4D7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000070228.
KOiK01580.
OMAiENCRENM.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

A1C4D7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHLSRVQKR TTPRRHANTK DVTDFVYGTR FAVEDLPRHQ MAEKEMPPEV
60 70 80 90 100
VYRLVKDELS LDGNPMLNLA SFVTTYMEDE VQNLMTDALS KNFIDFEEYP
110 120 130 140 150
QTSEIQNRCV NMIAELLHAP TTADGPDAQD AIGTSTIGSS EAIMLATLAM
160 170 180 190 200
KRRWQNRRKA EGKDASRPNL IMNTAVHVCW EKAARYFDVE EKYVYCTETR
210 220 230 240 250
FVIDPQEAVD MVDENTIGIC TILGTTYTGQ YEDVKAINDL LTERNIDCPI
260 270 280 290 300
HVDAASGGFV APFVNPSLKW DFQLPKVVSI NISGHKYGLV YPGIGWVFWR
310 320 330 340 350
STEYLPQDLV FNVNYLGSEQ ATFTLNFSKG AANIIGQYYQ LLRLGKHGYR
360 370 380 390 400
AIMNTLSRIA DHLAAELTNL GFIIMSDSGG NNLPLVAYRL PPNEDRLYDE
410 420 430 440 450
YALAHVLRQR GWIVPAYTMA PKANNLKMMR VVLRDDFSMN RCEALIADIK
460 470 480 490 500
MAMKSLDDMD AQMIQKYMER AAHQNKPLVD RQAAPVYQNE KHSLQGKTGK

THAIC
Length:505
Mass (Da):57,216
Last modified:January 23, 2007 - v1
Checksum:i0E26ED2215D48455
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS026990 Genomic DNA. Translation: EAW15277.1.
RefSeqiXP_001276703.1. XM_001276702.1.

Genome annotation databases

EnsemblFungiiCADACLAT00005457; CADACLAP00005332; CADACLAG00005457.
GeneIDi4708796.
KEGGiact:ACLA_059420.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS026990 Genomic DNA. Translation: EAW15277.1.
RefSeqiXP_001276703.1. XM_001276702.1.

3D structure databases

ProteinModelPortaliA1C4D7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5057.CADACLAP00005332.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADACLAT00005457; CADACLAP00005332; CADACLAG00005457.
GeneIDi4708796.
KEGGiact:ACLA_059420.

Organism-specific databases

EuPathDBiFungiDB:ACLA_059420.

Phylogenomic databases

HOGENOMiHOG000070228.
KOiK01580.
OMAiENCRENM.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1Imported.

Entry informationi

Entry nameiA1C4D7_ASPCL
AccessioniPrimary (citable) accession number: A1C4D7
Entry historyi
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: April 29, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.