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A1C499 (BTGE_ASPCL) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable beta-glucosidase btgE

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase btgE
Cellobiase btgE
Gentiobiase btgE
Gene names
Name:btgE
ORF Names:ACLA_059020
OrganismAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1) [Complete proteome]
Taxonomic identifier344612 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length564 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose By similarity.

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Subcellular location

Secretedcell wall By similarity. Note: Covalently-linked to the cell wall By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 17 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Cellular componentCell wall
Secreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcell wall

Inferred from electronic annotation. Source: UniProtKB-SubCell

extracellular region

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Chain19 – 564546Probable beta-glucosidase btgE
PRO_0000395130

Sites

Active site5011Nucleophile By similarity
Active site5551Proton donor By similarity

Amino acid modifications

Glycosylation4041N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A1C499 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: B95D30B0D0B75AF0

FASTA56458,575
        10         20         30         40         50         60 
MRGAFLATAA AIAGTAMADI AHMRRHGHDS FHQRRAVEQP APEADATCGC TTEVVTSWGP 

        70         80         90        100        110        120 
PTLIPIATSS PSSTVTSEVV TTLHSTSYST VTLVVTPSGA SPNRESAPAT PAVTLPTPGV 

       130        140        150        160        170        180 
TSFSTTGTYT IPATTLTVTH STTVCGATTT ELPSGTHTYG GVTTVVDRHT TVVCPYATVE 

       190        200        210        220        230        240 
PSGSTVTSVI RTTTYVCPSA GTYTIAPTTT YVPTSTVIVY PTPATITPGT YTQPAQTITV 

       250        260        270        280        290        300 
TRDNYIYVCP FTGQQLPTTA PVAPATTAVP ATTTAVPATT TAVPATSSVA PSSSPSKPAA 

       310        320        330        340        350        360 
PSGAVSGQMG MTYSPYTNEG GCKDKASIIS EVALLKSKGF THVRVYSTDC GSLEFIGEAA 

       370        380        390        400        410        420 
RTSGLRMIIG VFIKQSGVAG AQDQVTAISK WAQWDLVSLI VVGNESIQNH FCDASTLAGF 

       430        440        450        460        470        480 
IVSAKQSFKA AGYSGQVTTT EPINVWQANG DALCGAVDII GANIHPFFNA DVSAAEAGKF 

       490        500        510        520        530        540 
VAQEFKTLKG ICPGKDVINL ETGWPHSGEA NGKAIPSREE QAIAIKAIAD EVGSMSVFFS 

       550        560 
YFDDLWKQPG AFGVERYWGC IENF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS026990 Genomic DNA. Translation: EAW15239.1.
RefSeqXP_001276665.1. XM_001276664.1.

3D structure databases

ProteinModelPortalA1C499.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5057.CADACLAP00005509.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADACLAT00005634; CADACLAP00005509; CADACLAG00005634.
GeneID4708849.
KEGGact:ACLA_059020.

Phylogenomic databases

eggNOGCOG5309.
HOGENOMHOG000158427.
OMAYSTDCDT.
OrthoDBEOG73FQWG.

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
ProtoNetSearch...

Entry information

Entry nameBTGE_ASPCL
AccessionPrimary (citable) accession number: A1C499
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: January 23, 2007
Last modified: March 19, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries