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Protein

Arsenate reductase

Gene

arsC

Organism
Bacillus cereus
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].UniRule annotation

Catalytic activityi

Arsenate + thioredoxin = arsenite + thioredoxin disulfide + H2O.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei11NucleophileUniRule annotation1
Active sitei83NucleophileUniRule annotation1
Active sitei90NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processArsenical resistanceUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Arsenate reductaseUniRule annotation (EC:1.20.4.4UniRule annotation)
Gene namesi
Name:arsCUniRule annotationImported
ORF Names:A9485_23380Imported, AT274_07330Imported, B4088_5097Imported, B4155_4154Imported, BC141101_01194Imported, BCF24048_05571Imported, BG11_5513Imported, BJR07_28695Imported, pPER272_0253Imported, pPER272_AH820_0253Imported, TQ94_28665Imported, TU58_02105Imported
Encoded oniPlasmid pBFC_3Imported
Plasmid pPER272Imported
OrganismiBacillus cereusImported
Taxonomic identifieri1396 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000195263 Componenti: Unassembled WGS sequence
  • UP000075591 Componenti: Unassembled WGS sequence
  • UP000036308 Componenti: Unassembled WGS sequence
  • UP000031856 Componenti: Plasmid pBFC_3
  • UP000076594 Componenti: Unassembled WGS sequence
  • UP000196277 Componenti: Unassembled WGS sequence
  • UP000183583 Componenti: Unassembled WGS sequence
  • UP000036243 Componenti: Unassembled WGS sequence
  • UP000186535 Componenti: Unassembled WGS sequence
  • UP000076482 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi11 ↔ 83Redox-active; alternateUniRule annotation
Disulfide bondi83 ↔ 90Redox-active; alternateUniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 132LMWPcInterPro annotationAdd BLAST128

Sequence similaritiesi

Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.UniRule annotation

Keywords - Domaini

Redox-active centerUniRule annotation

Family and domain databases

HAMAPiMF_01624. Arsenate_reduct. 1 hit.
InterProiView protein in InterPro
IPR014064. Arsenate_reductase_ArsC.
IPR023485. Ptyr_pPase.
IPR036196. Ptyr_pPase_sf.
PfamiView protein in Pfam
PF01451. LMWPc. 1 hit.
SMARTiView protein in SMART
SM00226. LMWPc. 1 hit.
SUPFAMiSSF52788. SSF52788. 1 hit.
TIGRFAMsiTIGR02691. arsC_pI258_fam. 1 hit.

Sequencei

Sequence statusi: Complete.

A1BZS8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENKKTIYFL CTGNSCRSQM AEAWGKKYLG DKWNVLSAGI EAHGVNPNAI
60 70 80 90 100
KAMKEVDIDI TDQTSDIIDR DILDKADLVV TLCGHANDVC PTTPPHVKRV
110 120 130
HWGFDDPAGQ EWSVFQRVRD EIGARIKKYA ETGE
Length:134
Mass (Da):15,006
Last modified:January 23, 2007 - v1
Checksum:i63A6D7AE747B42D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ889677 Genomic DNA. Translation: ABK00849.1.
DQ889678 Genomic DNA. Translation: ABK01114.1.
CP009595 Genomic DNA. Translation: AJH60299.1.
JYFW01000044 Genomic DNA. Translation: KMP12841.1.
LABH01000007 Genomic DNA. Translation: KMQ32061.1.
LOMT01000002 Genomic DNA. Translation: KXY04163.1.
LJKE01000096 Genomic DNA. Translation: KZD56469.1.
LJKJ01000067 Genomic DNA. Translation: KZD75933.1.
LZQY01000019 Genomic DNA. Translation: OJE00931.1.
MPON01000023 Genomic DNA. Translation: OKA32232.1.
FMJG01000039 Genomic DNA. Translation: SCN02949.1.
FMJK01000006 Genomic DNA. Translation: SCN16024.1.
RefSeqiWP_000428327.1. NZ_MUAO01000028.1.

Genome annotation databases

EnsemblBacteriaiKMP12841; KMP12841; TQ94_28665.
KMQ32061; KMQ32061; TU58_02105.
KXY04163; KXY04163; AT274_07330.
KXY85044; KXY85044; AT258_00985.
KZD56469; KZD56469; B4088_5097.
KZD75933; KZD75933; B4155_4154.
PATRICifig|1396.430.peg.389.

Similar proteinsi

Entry informationi

Entry nameiA1BZS8_BACCE
AccessioniPrimary (citable) accession number: A1BZS8
Entry historyiIntegrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: October 25, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported, PlasmidImported