A1BN54 (A1BN54_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Alpha actinin 1a EMBL ABB88726.1

Submitted name:
Uncharacterized protein Ensembl ENSMUSP00000127176

Gene names

Name:	Actn1 Ensembl ENSMUSP00000127176 MGI 2137706
Synonyms:	Actn1a EMBL ABB88726.1

Organism

Mus musculus (Mouse) EMBL ABB88726.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	887 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Repeat SAAS SAAS018159
Ligand	Actin-binding SAAS SAAS018159
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	Z disc Inferred from direct assay. Source: MGI fascia adherens Inferred from direct assay. Source: MGI
Molecular function	actin filament binding Inferred from direct assay. Source: MGI calcium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1BN54 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: 3DE9A4FB303F7F8A	FASTA	887	102,720
	10 20 30 40 50 60 MDHYDSQQTN DYMQPEEDWD RDLLLDPAWE KQQRKTFTAW CNSHLRKAGT QIENIEEDFR 70 80 90 100 110 120 DGLKLMLLLE VISGERLAKP ERGKMRVHKI SNVNKALDFI ASKGVKLVSI GAEEIVDGNV 130 140 150 160 170 180 KMTLGMIWTI ILRFAIQDIS VEETSAKEGL LLWCQRKTAP YKNVNIQNFH ISWKDGLGFC 190 200 210 220 230 240 ALIHRHRPEL IDYGKLRKDD PLTNLNTAFD VAERFLDIPK MLDAEDIVGT ARPDEKAIMT 250 260 270 280 290 300 YVSSFYHAFS GAQKAETAAN RICKVLAVNQ ENEQLMEDYE KLASDLLEWI RRTIPWLENR 310 320 330 340 350 360 VPENTMHAMQ QKLEDFRDYR RLHKPPKVQE KCQLEINFNT LQTKLRLSNR PAFMPSEGRM 370 380 390 400 410 420 VSDINNAWGC LEQAEKGYEE WLLNEIRRLE RLDHLAEKFR QKASIHEAWT DGKEAMLRQK 430 440 450 460 470 480 DYETATLSEI KALLKKHEAF ESDLAAHQDR VEQIAAIAQE LNELDYYDSP SVNARCQKIC 490 500 510 520 530 540 DQWDNLGALT QKRREALERT EKLLETIDQL YLEYAKRAAP FNNWMEGAME DLQDTFIVHT 550 560 570 580 590 600 IEEIQGLTTA HEQFKATLPD ADKERLAILG IHNEVSKIVQ TYHVNMAGTN PYTTITPQEI 610 620 630 640 650 660 NGKWDHVRQL VPRRDQALTE EHARQQHNER LRKQFGAQAN VIGPWIQTKM EEIGRISIEM 670 680 690 700 710 720 HGTLEDQLSH LRQYEKSIVN YKPKIDQLEC DHQLIQEALI FDNKHTNYNM EHIRVGWEQL 730 740 750 760 770 780 LTTIARTINE VENQILTRDA KGISQEQMNE FRASFNHFDR KKTGMMDTDD FRACLISMGY 790 800 810 820 830 840 NMGEAEFARI MSIVDPNRLG VVTFQAFIDF MSRETADTDT ADQVMASFKI LAGDKNYITE 850 860 870 880 DELRRELPPD QAEYCIARMA PYAGPDSVPG ALDYMSFSTA LYGESDL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Differential binding of cross-reactive anti-DNA antibodies to mesangial cells: the role of alpha-actinin." Zhao Z., Deocharan B., Scherer P.E., Ozelius L.J., Putterman C. J. Immunol. 176:7704-7714(2006) [PubMed: 16751418] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: BALB/c EMBL ABB88726.1.
[2]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Mouse Genome Sequencing Consortium Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6 Ensembl ENSMUSP00000127176.
[3]	Ensembl Submitted (JUN-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000127176.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC108401 Genomic DNA. No translation available. CT030161 Genomic DNA. No translation available. DQ288940 mRNA. Translation: ABB88726.1.
IPI	IPI00989903.
UniGene	Mm.253564. Mm.403477.
3D structure databases
ProteinModelPortal	A1BN54.
SMR	A1BN54. Positions 30-254, 267-887.
ModBase	Search...
Protein-protein interaction databases
IntAct	A1BN54. 3 interactions.
STRING	A1BN54.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000167327; ENSMUSP00000127176; ENSMUSG00000015143.
UCSC	uc007oaq.2. mouse.
Organism-specific databases
MGI	MGI:2137706. Actn1.
Phylogenomic databases
eggNOG	roNOG11088.
HOVERGEN	HBG050453.
InParanoid	A1BN54.
Gene expression databases
Bgee	A1BN54.
Genevestigator	A1BN54.
Family and domain databases
InterPro	IPR001589. Actinin_actin-bd_CS. IPR001715. CH-domain. IPR011992. EF-hand-like_dom. IPR014837. EF-hand_Ca_insen. IPR018249. EF_HAND_2. IPR002048. EF_hand_Ca-bd. IPR018159. Spectrin/alpha-actinin. IPR002017. Spectrin_repeat. [Graphical view]
Gene3D	G3DSA:1.10.418.10. Calponin-homology. 2 hits. G3DSA:1.10.238.10. EF-Hand_type. 2 hits.
Pfam	PF00307. CH. 2 hits. PF08726. efhand_Ca_insen. 1 hit. PF00435. Spectrin. 4 hits. [Graphical view]
SMART	SM00033. CH. 2 hits. SM00054. EFh. 2 hits. SM00150. SPEC. 2 hits. [Graphical view]
SUPFAM	SSF47576. Calponin-homology. 1 hit.
PROSITE	PS00019. ACTININ_1. 1 hit. PS00020. ACTININ_2. 1 hit. PS50021. CH. 2 hits. PS50222. EF_HAND_2. 2 hits. [Graphical view]
ProtoNet	Search...
Other
SOURCE	Search...

Entry information

Entry name

A1BN54_MOUSE

Accession

Primary (citable) accession number: A1BN54

Entry history

Integrated into UniProtKB/TrEMBL:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	November 16, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)