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Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Chlorobium phaeobacteroides (strain DSM 266)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease, RNA-binding
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P proteinUniRule annotation
Short name:
RNaseP proteinUniRule annotation
Alternative name(s):
Protein C5UniRule annotation
Gene namesi
Name:rnpAUniRule annotation
Ordered Locus Names:Cpha266_2742
OrganismiChlorobium phaeobacteroides (strain DSM 266)
Taxonomic identifieri290317 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
Proteomesi
  • UP000008701 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001946201 – 146Ribonuclease P protein componentAdd BLAST146

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

Protein-protein interaction databases

STRINGi290317.Cpha266_2742.

Structurei

3D structure databases

SMRiA1BJZ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000155258.
KOiK03536.
OMAiKHEILRK.
OrthoDBiPOG091H011Y.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
HAMAPiMF_00227. RNase_P. 1 hit.
InterProiView protein in InterPro
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
IPR020539. RNase_P_CS.
PfamiView protein in Pfam
PF00825. Ribonuclease_P. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD003629. Ribonuclease_P. 1 hit.
SUPFAMiSSF54211. SSF54211. 1 hit.
PROSITEiView protein in PROSITE
PS00648. RIBONUCLEASE_P. 1 hit.

Sequencei

Sequence statusi: Complete.

A1BJZ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHHEVMSGLH VNSLRKHEIL RKEQLIAALF VSGKSCKGEY LKLFYQKTVS
60 70 80 90 100
DVKSRSPAVQ VLFAVSKKNV PHAVSRNRLK RLMREAYRNE KQQLFTLCDE
110 120 130 140
GRPEMSGIHL QIAVLYIGGR KSFPSFELLR QEISRLMHNI RLSELT
Length:146
Mass (Da):16,903
Last modified:January 23, 2007 - v1
Checksum:i40A727311DCE239D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000492 Genomic DNA. Translation: ABL66726.1.

Genome annotation databases

EnsemblBacteriaiABL66726; ABL66726; Cpha266_2742.
KEGGicph:Cpha266_2742.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRNPA_CHLPD
AccessioniPrimary (citable) accession number: A1BJZ9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: January 23, 2007
Last modified: June 7, 2017
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families