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A1BIP9

- A1BIP9_CHLPD

UniProt

A1BIP9 - A1BIP9_CHLPD

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Protein

Alanine racemase

Gene

Cpha266_2284

Organism
Chlorobium phaeobacteroides (strain DSM 266)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei42 – 421Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei143 – 1431SubstrateUniRule annotation
Active sitei270 – 2701Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei318 – 3181Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciCPHA290317:GHX4-2325-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Cpha266_2284Imported
OrganismiChlorobium phaeobacteroides (strain DSM 266)Imported
Taxonomic identifieri290317 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
ProteomesiUP000008701: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei42 – 421N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi290317.Cpha266_2284.

Structurei

3D structure databases

ProteinModelPortaliA1BIP9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiAEININN.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.

Sequencei

Sequence statusi: Complete.

A1BIP9 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTIETPSLNM AEASISLGHL KHNIREIKQC VGTGVRIMGI VKANAYGHNM
60 70 80 90 100
QKVAETLEAE GISDFGVANI HEAIELKTGG ALKKPANILS FSSPIIQQIE
110 120 130 140 150
YYLHHQIDMT LCDANIMKAA SAIAEKHNKK IGVHLKVDTG MGRLGLPPLQ
160 170 180 190 200
ALELLRETER QPGLELKGVY THFAESANDD FTRRQFKEFK TMTDAYETAS
210 220 230 240 250
GKTLCKHAAS SGTLLNNPEM RLDMVRPGIL LYGYKPYPAL PSSITVRPVM
260 270 280 290 300
QFEAKVIFIK TVAKDATISY NRTWKAARPV KIATISAGYA DGYHRALSNH
310 320 330 340 350
ATVFINGKSF QQVGTVTMDQ FMVDLGTESD VKIGDRAILF GWEGPCLEEL
360 370
AGSIGSISYE LLCSVSSRVK RVFTDD
Length:376
Mass (Da):41,326
Last modified:January 23, 2007 - v1
Checksum:iE6941383C76C1B48
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000492 Genomic DNA. Translation: ABL66276.1.
RefSeqiYP_912700.1. NC_008639.1.

Genome annotation databases

EnsemblBacteriaiABL66276; ABL66276; Cpha266_2284.
GeneIDi4568700.
KEGGicph:Cpha266_2284.
PATRICi21393141. VBIChlPha122104_2730.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000492 Genomic DNA. Translation: ABL66276.1 .
RefSeqi YP_912700.1. NC_008639.1.

3D structure databases

ProteinModelPortali A1BIP9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290317.Cpha266_2284.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABL66276 ; ABL66276 ; Cpha266_2284 .
GeneIDi 4568700.
KEGGi cph:Cpha266_2284.
PATRICi 21393141. VBIChlPha122104_2730.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi AEININN.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci CPHA290317:GHX4-2325-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Chlorobium phaeobacteroides DSM 266."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J., Bryant D.A., Richardson P.
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 266Imported.

Entry informationi

Entry nameiA1BIP9_CHLPD
AccessioniPrimary (citable) accession number: A1BIP9
Entry historyi
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3