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A1BIP2 (AROA_CHLPD) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:Cpha266_2277
OrganismChlorobium phaeobacteroides (strain DSM 266) [Complete proteome] [HAMAP]
Taxonomic identifier290317 [NCBI]
Taxonomic lineageBacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4344343-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000099681

Sequences

Sequence LengthMass (Da)Tools
A1BIP2 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: DB498B56D2853E60

FASTA43446,577
        10         20         30         40         50         60 
MSVFKGEVTA LPPDKSISHR AALIGALSDG TTEIVNFSGG FDNQSTLAVL QASGIALIQE 

        70         80         90        100        110        120 
ECAGSYGRRI RRVVIESRGL WSFLAPQAPL MCNNSGSTMR MFAGILAAQP FESVLEGDSS 

       130        140        150        160        170        180 
LMKRPMNRVA DPLRQMGAQV ELSFSGTAPI RIQGTKDLHS LEYRLPVSSA QVKSLVAFAA 

       190        200        210        220        230        240 
LHADGQTRII EPIRSRDHTE LMLGLETIDQ PNGERVIIVP GRKRIESKPF YIPADPSAAC 

       250        260        270        280        290        300 
FIVALALLAK GSDIIIRDLC LNPTRTGYLA ILAGAGAGIS VENSRVIGGE AIGDVLVHSE 

       310        320        330        340        350        360 
GELNSLVISD PHEVANVIDE IPMLAVLSAF SSGRFELHHA AELRTKESDR IDALVVNLER 

       370        380        390        400        410        420 
LGFQCEQYPD GFKVNGRIAM PKGVVSIESF DDHRIAMSFA IAGKATGVDL AISDIGVVGV 

       430 
SFPNFFEIIE SLEV

« Hide

References

[1]"Complete sequence of Chlorobium phaeobacteroides DSM 266."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J., Bryant D.A., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 266.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000492 Genomic DNA. Translation: ABL66269.1.
RefSeqYP_912693.1. NC_008639.1.

3D structure databases

ProteinModelPortalA1BIP2.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1BIP2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4568693.
GenomeReviewsGene locus Cpha266_2277 in contig CP000492_GR.
KEGGcph:Cpha266_2277.
NMPDRfig|290317.7.peg.2389.
PATRIC21393127. VBIChlPha122104_2723.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0128.
HOGENOMHBG646626.
OMALECANIS.
ProtClustDBPRK02427.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. False negative.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_CHLPD
AccessionPrimary (citable) accession number: A1BIP2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: January 23, 2007
Last modified: January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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