A1BI19 (SURE_CHLPD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	Cpha266_2034

Organism

Chlorobium phaeobacteroides (strain DSM 266) [Complete proteome] [HAMAP]

Taxonomic identifier

290317 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length	258 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 258	258	5'-nucleotidase surE HAMAP MF_00060		PRO_0000335256
Sites
	Metal binding	14	1	Divalent metal cation By similarity
	Metal binding	15	1	Divalent metal cation By similarity
	Metal binding	45	1	Divalent metal cation By similarity
	Metal binding	101	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1BI19 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: 756848703819E560	FASTA	258	28,386
	10 20 30 40 50 60 MDQLKKPHIL LCNDDGIEGE GLHALAASMK KIGNITVVAP AEPHSGMSHA MTLGTPLRIK 70 80 90 100 110 120 KYYKNNRFFG YTVSGTPVDC VKVALSQILP SKPDLLVSGI NYGSNTATNT LYSGTVAAAL 130 140 150 160 170 180 EGAIQGITSL AFSLATYENA DFSYAAKFAR KLSKKVLTEG LPPDTILSVN IPNIPESEIQ 190 200 210 220 230 240 GILVTEQGRS RWEEDAIERH DVYGNPYYWL NGTLMLLDTS LQHDEYAVRK HYVAVTPISC 250 DFTNRDFMGS LEQWNLKK

References

[1]

"Complete sequence of Chlorobium phaeobacteroides DSM 266." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J., Bryant D.A., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 266.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000492 Genomic DNA. Translation: ABL66046.1.
RefSeq	YP_912470.1. NC_008639.1.
3D structure databases
ProteinModelPortal	A1BI19.
ModBase	Search...
Protein-protein interaction databases
STRING	A1BI19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4569154.
GenomeReviews	Gene locus Cpha266_2034 in contig CP000492_GR.
KEGG	cph:Cpha266_2034.
NMPDR	fig|290317.7.peg.2149.
PATRIC	21392526. VBIChlPha122104_2423.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0496.
HOGENOM	HBG600532.
OMA	SINVIYS.
PhylomeDB	A1BI19.
ProtClustDB	PRK13932.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_CHLPD

Accession

Primary (citable) accession number: A1BI19

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 20, 2008
Last sequence update:	January 23, 2007
Last modified:	January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program