A1BGZ4 (SYD_CHLPD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Aspartate--tRNA ligase
EC=6.1.1.12

Alternative name(s):
Aspartyl-tRNA synthetase
Short name=AspRS

Gene names

Name:	aspS
Ordered Locus Names:	Cpha266_1650

Organism

Chlorobium phaeobacteroides (strain DSM 266) [Complete proteome] [HAMAP]

Taxonomic identifier

290317 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length	606 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). HAMAP MF_00044_B
Subunit structure	Homodimer By similarity. HAMAP MF_00044_B
Subcellular location	Cytoplasm By similarity HAMAP MF_00044_B.
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA aminoacylation for protein translation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW aspartate-tRNA ligase activity Inferred from electronic annotation. Source: EC nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 606	606	Aspartate--tRNA ligase HAMAP MF_00044_B		PRO_1000057300

Sequences

	Sequence		Length	Mass (Da)
	A1BGZ4 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: 3259DAB6BB92CCFE	FASTA	606	68,832
	10 20 30 40 50 60 MSRAAGSTET LKNRFRTDYC GLLNPEVEHQ SVKLGGWVHR KRDHGGLIFI DLRDHTGICQ 70 80 90 100 110 120 IVIQPEEQQL FAKAEQLHLE SVICIEGTVV RRSPGAVNPR IPSGEIEVVA AGISVESSAH 130 140 150 160 170 180 PLPFPVADEV QTSEELRLKY RFIDLRRDKI HENIIFRSRL TAAIRRYLEE KSFIEIQTPI 190 200 210 220 230 240 LTSSSPEGAR DFLVPSRLHP GKFYALPQAP QQFKQLLMVS GFPRYFQIAP CFRDEDARAD 250 260 270 280 290 300 RSPGEFYQLD MEMAFIEQDD LFEILEGMFS HLTGSMSTKR IREFPFPRIS FRDVMNRYGT 310 320 330 340 350 360 DKPDLRIPLE ISDVTHLFLQ SSFKVFAANT KEGCCVKAML VKGRGNESRL FYDKAEKRAK 370 380 390 400 410 420 ELGSGGLAYI QFREDGPKGP LVKFLSGEEL AALRELLGVE VGDVVFFGAG KWEQTCRIMG 430 440 450 460 470 480 GMRTYFSDLF TLDRDELAFC WVVDFPMYEY NEDQKKIDFS HNPFSMPQGE MDALESMPPL 490 500 510 520 530 540 NILAYQYDIV CNGIELSSGA IRNHRPDIMY KAFEIAGYTK EDVDSRFGHM IEAFKLGAPP 550 560 570 580 590 600 HGGIAPGLDR LVMILRDEQN IREVIAFPMN QQAQDLMMGS PSEVTPIQLR ELHLQVELPK KAEAKP

References

[1]

"Complete sequence of Chlorobium phaeobacteroides DSM 266." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J., Bryant D.A., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 266.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000492 Genomic DNA. Translation: ABL65671.1.
RefSeq	YP_912095.1. NC_008639.1.
3D structure databases
ProteinModelPortal	A1BGZ4.
ModBase	Search...
Protein-protein interaction databases
STRING	A1BGZ4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4571030.
GenomeReviews	Gene locus Cpha266_1650 in contig CP000492_GR.
KEGG	cph:Cpha266_1650.
NMPDR	fig|290317.7.peg.1731.
PATRIC	21391568. VBIChlPha122104_1948.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0173.
HOGENOM	HBG396032.
OMA	YQLDVEM.
ProtClustDB	PRK00476.
Family and domain databases
HAMAP	MF_00044_B. Asp_tRNA_synth_B. [Tree]
InterPro	IPR004364. aa-tRNA-synt_II. IPR018150. aa-tRNA-synt_II-like. IPR006195. aa-tRNA-synth_II. IPR004524. Asp-tRNA-synth_IIb_bac/mt. IPR002312. Asp/Asn-tRNA-synth_IIb. IPR004115. GAD_dom. IPR012340. NA-bd_OB-fold. IPR016027. NA-bd_OB-fold-like. IPR004365. NA-bd_OB_tRNA-helicase. [Graphical view]
Gene3D	G3DSA:3.30.1360.30. GAD_dom. 1 hit. G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KO	K01876.
PANTHER	PTHR22594. aa-tRNA-synt_II. 1 hit. PTHR22594:SF5. AspS_bac. 1 hit.
Pfam	PF02938. GAD. 1 hit. PF00152. tRNA-synt_2. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
PRINTS	PR01042. TRNASYNTHASP.
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit. SSF55261. SSF55261. 1 hit.
TIGRFAMs	TIGR00459. AspS_bact. 1 hit.
PROSITE	PS50862. AA_TRNA_LIGASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYD_CHLPD

Accession

Primary (citable) accession number: A1BGZ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	January 23, 2007
Last modified:	January 25, 2012
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program