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A1BGS9

- TRMB_CHLPD

UniProt

A1BGS9 - TRMB_CHLPD

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Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene

trmB

Organism
Chlorobium phaeobacteroides (strain DSM 266)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei36 – 361S-adenosyl-L-methionineUniRule annotation
Binding sitei61 – 611S-adenosyl-L-methionineUniRule annotation
Active sitei111 – 1111By similarity
Binding sitei111 – 1111S-adenosyl-L-methionineUniRule annotation
Binding sitei115 – 1151SubstrateUniRule annotation
Binding sitei147 – 1471SubstrateUniRule annotation

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciCPHA290317:GHX4-1614-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation (EC:2.1.1.33UniRule annotation)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferaseUniRule annotation
tRNA(m7G46)-methyltransferaseUniRule annotation
Gene namesi
Name:trmBUniRule annotation
Ordered Locus Names:Cpha266_1584
OrganismiChlorobium phaeobacteroides (strain DSM 266)
Taxonomic identifieri290317 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
ProteomesiUP000008701: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 204204tRNA (guanine-N(7)-)-methyltransferasePRO_0000288136Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi290317.Cpha266_1584.

Structurei

3D structure databases

ProteinModelPortaliA1BGS9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni177 – 1804Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000064302.
KOiK03439.
OMAiGFEVENS.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1BGS9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFMDSRETLC ENPVIITDRD AWKEINLKDA GTIEVEIGFG SGEYLLRRAS
60 70 80 90 100
EYPERLFIGI EKKPGMITEV SKRVASHNLN NIRLLESCAK DAFADLFPAN
110 120 130 140 150
SISRVYSLFP DPWPKRKHLH YRLFSSEYLR LLNNRLIFGS EALIVTDSED
160 170 180 190 200
YCNWMLKQLP DTGFEVENSI IPPQFDTRFE RKWLEQNFNT FFRILLKKAR

HIET
Length:204
Mass (Da):23,956
Last modified:January 23, 2007 - v1
Checksum:i54317EB62E18A688
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000492 Genomic DNA. Translation: ABL65606.1.
RefSeqiWP_011745416.1. NC_008639.1.
YP_912030.1. NC_008639.1.

Genome annotation databases

EnsemblBacteriaiABL65606; ABL65606; Cpha266_1584.
GeneIDi4569766.
KEGGicph:Cpha266_1584.
PATRICi21391391. VBIChlPha122104_1865.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000492 Genomic DNA. Translation: ABL65606.1 .
RefSeqi WP_011745416.1. NC_008639.1.
YP_912030.1. NC_008639.1.

3D structure databases

ProteinModelPortali A1BGS9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290317.Cpha266_1584.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABL65606 ; ABL65606 ; Cpha266_1584 .
GeneIDi 4569766.
KEGGi cph:Cpha266_1584.
PATRICi 21391391. VBIChlPha122104_1865.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000064302.
KOi K03439.
OMAi GFEVENS.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci CPHA290317:GHX4-1614-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Chlorobium phaeobacteroides DSM 266."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J., Bryant D.A., Richardson P.
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 266.

Entry informationi

Entry nameiTRMB_CHLPD
AccessioniPrimary (citable) accession number: A1BGS9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3