Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Chlorobium phaeobacteroides (strain DSM 266)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathway: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathway: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. ATP-dependent 6-phosphofructokinase (pfkA), ATP-dependent 6-phosphofructokinase (pfkA)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei352 – 3521Proton donorUniRule annotation
Active sitei383 – 3831UniRule annotation
Active sitei511 – 5111UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCPHA290317:GHX4-1121-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Cpha266_1095
OrganismiChlorobium phaeobacteroides (strain DSM 266)
Taxonomic identifieri290317 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
ProteomesiUP000008701 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 559559Glucose-6-phosphate isomerasePRO_1000013951Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi290317.Cpha266_1095.

Structurei

3D structure databases

ProteinModelPortaliA1BFF9.
SMRiA1BFF9. Positions 14-546.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1BFF9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELSRSAAWS ALVFHKHEVD KKTMRDMFAG DSDRFVKFSL SWKEMLLDYS
60 70 80 90 100
KNRITSRTME LLLELAHSAG VDEKRQQMFQ GAPINFTENR SVLHTALRRP
110 120 130 140 150
PGYVLEVDGL NIGDEIAGVL FQMKNFCEKV ISGKWKGYTG KSITDVVNIG
160 170 180 190 200
IGGSDLGPYM VTEALKPFAH GGLDVHFVSN IDGTHIRETL KRLDPETTLF
210 220 230 240 250
IIASKTFTTQ ETLTNAMSAR EWFLARAVEE EYIKKHFAAV STNQEKVVEF
260 270 280 290 300
GIDDANMFRF WDWVGGRYSL WSSIGLSIAL YLGFNRFEEL LAGAHAMDEH
310 320 330 340 350
FLNEPFNRNI PVILALLGIW YRNFFDAASH AVIPYDQYLH RFPAYLQQLD
360 370 380 390 400
MESNGKRVDE NGHTVTHATG PVIWGEPGTN AQHAFFQLLH QGPDLIPADF
410 420 430 440 450
IVPLKSQNPS GEHHDMLLAN CFAQTEALMK GKTEQEVRAE LSDAGYDEAD
460 470 480 490 500
IQKLFQHKVF SGNRPTNTIL VHELNPFMLG SLIAMYEHKV FVQGVIWRIN
510 520 530 540 550
SFDQWGVELG KQLARTILPE IQSAEAVTAH DASTNALINM ARTFREENIR

KESAQLSFF
Length:559
Mass (Da):63,299
Last modified:January 23, 2007 - v1
Checksum:iE5D48385E1B241FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000492 Genomic DNA. Translation: ABL65136.1.
RefSeqiWP_011744962.1. NC_008639.1.
YP_911560.1. NC_008639.1.

Genome annotation databases

EnsemblBacteriaiABL65136; ABL65136; Cpha266_1095.
KEGGicph:Cpha266_1095.
PATRICi21390175. VBIChlPha122104_1259.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000492 Genomic DNA. Translation: ABL65136.1.
RefSeqiWP_011744962.1. NC_008639.1.
YP_911560.1. NC_008639.1.

3D structure databases

ProteinModelPortaliA1BFF9.
SMRiA1BFF9. Positions 14-546.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi290317.Cpha266_1095.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABL65136; ABL65136; Cpha266_1095.
KEGGicph:Cpha266_1095.
PATRICi21390175. VBIChlPha122104_1259.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiFELANDC.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.
BioCyciCPHA290317:GHX4-1121-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Chlorobium phaeobacteroides DSM 266."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J., Bryant D.A., Richardson P.
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 266.

Entry informationi

Entry nameiG6PI_CHLPD
AccessioniPrimary (citable) accession number: A1BFF9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 23, 2007
Last modified: April 1, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.