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Protein

UvrABC system protein C

Gene

uvrC

Organism
Chlorobium phaeobacteroides (strain DSM 266)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:Cpha266_0710
OrganismiChlorobium phaeobacteroides (strain DSM 266)
Taxonomic identifieri290317 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobium/Pelodictyon groupChlorobium
Proteomesi
  • UP000008701 Componenti: Chromosome

Subcellular locationi

A1BED8:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000777681 – 631UvrABC system protein CAdd BLAST631

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Protein-protein interaction databases

STRINGi290317.Cpha266_0710.

Structurei

3D structure databases

ProteinModelPortaliA1BED8.
SMRiA1BED8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 105GIY-YIGUniRule annotationAdd BLAST80
Domaini219 – 254UVRUniRule annotationAdd BLAST36

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CII. Bacteria.
COG0322. LUCA.
HOGENOMiHOG000279960.
KOiK03703.
OMAiLFPIRQC.
OrthoDBiPOG091H01BS.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC. 1 hit.
InterProiView protein in InterPro
IPR000305. GIY-YIG_endonuc.
IPR035901. GIY-YIG_endonuc_sf.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR036876. UVR_dom_sf.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
PfamiView protein in Pfam
PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
SMARTiView protein in SMART
SM00465. GIYc. 1 hit.
SM00278. HhH1. 1 hit.
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiView protein in PROSITE
PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.

Sequencei

Sequence statusi: Complete.

A1BED8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSNPLHHSN PPVGSLPLDK VASLPSSPGV YQFKNAQGRV IYIGKAKNLR
60 70 80 90 100
NRVRSYFRNP QQLFGKTLVM VGKIADIEVI ITSSEVEALI LENNLIKELK
110 120 130 140 150
PRYNVNLKDD KTYPYLVITN EPFPRILVTR QVKKDGSTWF GPYTEARQLR
160 170 180 190 200
SILDFIGSIF PIRSCKLRLS PENISRGKFK VCLDYHIHKC KGPCEGLLTE
210 220 230 240 250
EEYLLMIVEI TRLLKGKTSA TIRSLNERML SFAKELKFEQ AAELKTQIDS
260 270 280 290 300
LKRYAERQKV VTSDTLDRDV FAVASRNDDG CGVVFKIREG KLLGSERLYM
310 320 330 340 350
NNTEGVSVQD LLARVVERYY LETCNLLPDE IFLQTELPAE EKETLENLLI
360 370 380 390 400
SKISAEGKQK RTIRLTVPII GEKAHLIQLC RENARHHLEE YLIQKQKRGE
410 420 430 440 450
ALREHSGLIA LAELLHLPKT PNRIECFDNS HFHGTDYVSS MVAFVHGKAK
460 470 480 490 500
KSDYRKFKLK TVQGSDDYAA MHEVLTRRYS GTLSVELPLP DLIVVDGGKG
510 520 530 540 550
QLSTAVKVLV SLKLDIPVIG LAKRIEEIFT PHTSDPFNLP KTSPALKLIQ
560 570 580 590 600
QLRDEAHRFA VTYHRKLRTE RTLETELTTI QGIGEKTAQK LLRHFGSVDL
610 620 630
IRTAGVDELR AAAGNKTAAL LYRFYHPLEE G
Length:631
Mass (Da):71,553
Last modified:January 23, 2007 - v1
Checksum:i7A733CF5D1CE6949
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000492 Genomic DNA. Translation: ABL64765.1.
RefSeqiWP_011744595.1. NC_008639.1.

Genome annotation databases

EnsemblBacteriaiABL64765; ABL64765; Cpha266_0710.
KEGGicph:Cpha266_0710.

Similar proteinsi

Entry informationi

Entry nameiUVRC_CHLPD
AccessioniPrimary (citable) accession number: A1BED8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: January 23, 2007
Last modified: October 25, 2017
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families