A1BCH1 (A1BCH1_CHLPD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Chromosomal replication initiator protein DnaA HAMAP MF_00377

Gene names

Name:	dnaA HAMAP MF_00377
Ordered Locus Names:	Cpha266_0001

Organism

Chlorobium phaeobacteroides (strain DSM 266) [Complete proteome] [HAMAP]

Taxonomic identifier

290317 [NCBI]

Taxonomic lineage

Bacteria › Chlorobi › Chlorobia › Chlorobiales › Chlorobiaceae › Chlorobium/Pelodictyon group › Chlorobium

Protein attributes

Sequence length	490 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity. HAMAP MF_00377 RuleBase RU000577
Subcellular location	Cytoplasm By similarity HAMAP MF_00377.
Sequence similarities	Belongs to the DnaA family. HAMAP MF_00377 RuleBase RU004227

Ontologies

Keywords
Biological process	DNA replication HAMAP MF_00377 RuleBase RU000577
Cellular component	Cytoplasm HAMAP MF_00377
Ligand	ATP-binding HAMAP MF_00377 RuleBase RU000577 DNA-binding HAMAP MF_00377 RuleBase RU000577 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA-dependent DNA replication initiation Inferred from electronic annotation. Source: HAMAP regulation of DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA replication origin binding Inferred from electronic annotation. Source: HAMAP nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	192 – 199	8	ATP By similarity HAMAP MF_00377

Sequences

	Sequence		Length	Mass (Da)
	A1BCH1 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: 3BEE9054D8AE2F7C	FASTA	490	55,398
	10 20 30 40 50 60 MSEATNRVPE VKIPSNLHKP ILLEQQVWDS CLEAIREKIN PLAYKTWFSP IKPVNFSGSE 70 80 90 100 110 120 LTIQVPSQFF YEWIEENYSS FLKQALKDVI GSEAKLMYSI VMDKSQGQPV TIELPHQSTP 130 140 150 160 170 180 LSACSSDSSE STQIKNKEAF EKNLQRFETH LNPKYVFETL IRGDCNSLAF AASKSVAQNP 190 200 210 220 230 240 GLNAFNPLVI YGGVGLGKTH MMQAIGNSVR KNCLSEKVLY VSSEKFAVDF VNAIQNGKIQ 250 260 270 280 290 300 EFSSFYRNID VLIIDDIQFF AGKEKTQEEI FHIFNTLHQT NKQIILSSDR PIKDIKGIED 310 320 330 340 350 360 RLISRFNWGL SADIQPPDYE TRKAIILSKL EQSGVNLDES VIEFIATNVT ENVRELEGCI 370 380 390 400 410 420 VKLLAAQSLD NREIDLHFTK STLKDIIRHT TKQLTLDTIE KAVCSFFAIT PNDLKGKSKK 430 440 450 460 470 480 KEIATGRQIA MYLAKNLTES SLKTIGLHFG GRDHSTVIHA VNTVGNRMEQ QSDERKKIEE 490 LKKRIEILSM

References

[1]

"Complete sequence of Chlorobium phaeobacteroides DSM 266." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E., Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T., Overmann J., Bryant D.A., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 266.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000492 Genomic DNA. Translation: ABL64078.1.
RefSeq	YP_910502.1. NC_008639.1.
3D structure databases
ProteinModelPortal	A1BCH1.
ModBase	Search...
Protein-protein interaction databases
STRING	A1BCH1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4568532.
GenomeReviews	Gene locus Cpha266_0001 in contig CP000492_GR.
KEGG	cph:Cpha266_0001.
NMPDR	fig|290317.7.peg.1.
PATRIC	21387608. VBIChlPha122104_0001.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0593.
HOGENOM	HBG695666.
OMA	CHTLNAL.
PhylomeDB	A1BCH1.
ProtClustDB	PRK00149.
Family and domain databases
HAMAP	MF_00377. DnaA_bact. [Tree]
InterPro	IPR003593. ATPase_AAA+_core. IPR001957. Chromosome_initiator_DnaA. IPR020591. Chromosome_initiator_DnaA-like. IPR018312. Chromosome_initiator_DnaA_CS. IPR013159. DnaA_C. IPR013317. DnaA_Hda. IPR010921. Trp_repressor/repl_initiator. [Graphical view]
Gene3D	G3DSA:1.10.1750.10. DnaA_C. 1 hit.
KO	K02313.
Pfam	PF00308. Bac_DnaA. 1 hit. PF08299. Bac_DnaA_C. 1 hit. [Graphical view]
PRINTS	PR00051. DNAA.
SMART	SM00382. AAA. 1 hit. SM00760. Bac_DnaA_C. 1 hit. [Graphical view]
SUPFAM	SSF48295. Trp_repress_rep. 1 hit.
TIGRFAMs	TIGR00362. DnaA. 1 hit.
PROSITE	PS01008. DNAA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1BCH1_CHLPD

Accession

Primary (citable) accession number: A1BCH1

Entry history

Integrated into UniProtKB/TrEMBL:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)