A1BA11 (A1BA11_PARDP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	Pden_4291

Organism

Paracoccus denitrificans (strain Pd 1222) [Complete proteome] [HAMAP] EMBL ABL72355.1

Taxonomic identifier

318586 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Paracoccus

Protein attributes

Sequence length	1077 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1BA11 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: D3D45C19E906F194	FASTA	1,077	120,109
	10 20 30 40 50 60 MPDHHARPEI LLPPVEHPNP PADYVELAVT SAFSFLHGAS HPRELALAAH LMGYDALGIA 70 80 90 100 110 120 DLNSLAGVVR LHATAKKLHL RPVIGARIVL ADGTAFLAYP TDRAAYGRLA SLITKGRRHD 130 140 150 160 170 180 LAGNWQKKGR CDLNLADLAT HAQGMRLIWL PGDDLSPLPD LALRLPQLSH VAASWLYRGD 190 200 210 220 230 240 DRARINRLDR AAQAAGLSIV AVNDVHYHAP DRRPLQDVMT CIREGTTIAR AGLLLAQNAE 250 260 270 280 290 300 RHLKPPAEMV RLFADWPHAI RATREIADSC RFSLDELQYE YPRESVPPGL TPQQHLENLT 310 320 330 340 350 360 WQGADWRYPA GVPDKVRATL IKELALIREK KIAQYFLTIH DIVRFAEDRA ILHQGRGSAA 370 380 390 400 410 420 NSAVCYVLGI TPVDPAKHEL LFERFISQNR KEPPDIDVDF EHERREEVIQ HIYDRYRRDR 430 440 450 460 470 480 AGLCATVIHY RPRSAIREVG KVMGLSEDVT SALADTVWGS WGKDMSAADT MQAGLDLGDP 490 500 510 520 530 540 LLRRTVRLAE EMIGMPRHLS QHVGGFVLTE GPLSETVPIG NAAMPDRSFI EWDKDDIDEL 550 560 570 580 590 600 HILKVDVLAL GMLTCIRKCF ALIKAHYGKV LTLSDFDHDD QPTYKMLQRG DSIGTFQVES 610 620 630 640 650 660 RAQMAMLPRL KPKRFYDLVI QVAIVRPGPI QGNMVHPYLR RRAGLETVDF PGPRDGDPDE 670 680 690 700 710 720 LKNILFRTEG VPIFQEQAMK IAMVAAEFTP NEVDDLRKAM ATFRSRGTIG QLQDRMVGKM 730 740 750 760 770 780 VERGYTRDFA ERCFNQIKGF GDYGFPESHA AAFAHLAYVS AWLKCHHPAA FAAALLNSQP 790 800 810 820 830 840 MGFYAPAQIV RDARDHGVTV LPADVNISEW DNTLEPCDGT FALRLGLRQI DGLPEALAER 850 860 870 880 890 900 IKQARHEPYA DLADLKTRAG LDARAIRLIA AADGLRSMGL DRRAGLWQAR ALRDAPELPL 910 920 930 940 950 960 FGRRDEGPEP AVTLPAMPLY EHVTADYQTL RLSLKAHPMR FLRRSLTAQG YVPAAGLAAL 970 980 990 1000 1010 1020 SNRSRLRMAG IVLVRQRPGS ANGTCFVTLE DETGVANLVV WEKTFAQFRK VVMTARLLEV 1030 1040 1050 1060 1070 HGQLQRAEGV THIVAHWLGD RSEALLRLAG EAPAALPQPR PSHPRQVRIL PKSRDFH

References

[1]

"Complete sequence of chromosome 2 of Paracoccus denitrificans PD1222." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Spiro S., Richardson D.J., Moir J.W.B., Ferguson S.J., van Spanning R.J.M., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000490 Genomic DNA. Translation: ABL72355.1.
RefSeq	YP_918051.1. NC_008687.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1BA11.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4582841.
GenomeReviews	Gene locus Pden_4291 in contig CP000490_GR.
KEGG	pde:Pden_4291.
PATRIC	22859780. VBIParDen97112_4243.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	EQPAIRL.
ProtClustDB	CLSK773035.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A1BA11_PARDP

Accession

Primary (citable) accession number: A1BA11

Entry history

Integrated into UniProtKB/TrEMBL:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)