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Protein

Adenine deaminase

Gene

ade

Organism
Paracoccus denitrificans (strain Pd 1222)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciPDEN318586:GCVQ-2878-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:Pden_2836
OrganismiParacoccus denitrificans (strain Pd 1222)
Taxonomic identifieri318586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeParacoccus
Proteomesi
  • UP000000361 Componenti: Chromosome 2

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 597597Adenine deaminasePRO_0000292391Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi318586.Pden_2836.

Structurei

3D structure databases

ProteinModelPortaliA1B5X6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiYSHDSHN.
OrthoDBiEOG622PNM.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.

Sequencei

Sequence statusi: Complete.

A1B5X6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKETGMLKP WIEAQARLVE VAAGRAPADL VIRGGQWVNV HTREVIPGMD
60 70 80 90 100
VAVADGRVAY VGPDAGPSVG PGTQVIEADG RFMVPGLIDA HMHVESGMLT
110 120 130 140 150
PAGFAAAVIP HGTTTIFHDP HEIANVLGLE GVRLMRDESL LQPISMFTQM
160 170 180 190 200
PSCAPSAPGL ETTGQPITEG EVAQAMGWDG IVGLGEMMNF PGVASGDRQM
210 220 230 240 250
LTEIAATRAA GKTVGGHYAS PDLGRPFHAY VAGGANDDHE TTTEAQGIAR
260 270 280 290 300
VRQGMGCMMR LGSAWYDVES QITAITEKGL DPRFFILCTD DSHSGTLVND
310 320 330 340 350
GHMNRVVRHA VDCGCDPLVA IQMATINAAS HFGLERELGS ITPGRRADVI
360 370 380 390 400
LTSDLRSLPI ETVIAQGVVV AETGKLLVDC PRIAWPEAAR DSVHLGRSLT
410 420 430 440 450
GADFAVRATG DSARVRVIGV VENQAPTRAL TAQLPIRDGV VEPQGETCHI
460 470 480 490 500
ALVERHRGTG GVVNGFVSGF GYQGRMAVAS TVAHDSHHMI VVGTDRDSMA
510 520 530 540 550
AAANHLGRIG GGVTVFRDGE ELATVALPIA GLMSDRPAAE VAEAAQGIVK
560 570 580 590
AMQDCGCTLN NAYMQHSLLA LVVIPELRIS DLGIVDVTRF ELVDLMV
Length:597
Mass (Da):62,923
Last modified:January 23, 2007 - v1
Checksum:iB2A9C858E78F1AF5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000490 Genomic DNA. Translation: ABL70920.1.
RefSeqiWP_011749111.1. NC_008687.1.

Genome annotation databases

EnsemblBacteriaiABL70920; ABL70920; Pden_2836.
KEGGipde:Pden_2836.
PATRICi22856822. VBIParDen97112_2775.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000490 Genomic DNA. Translation: ABL70920.1.
RefSeqiWP_011749111.1. NC_008687.1.

3D structure databases

ProteinModelPortaliA1B5X6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi318586.Pden_2836.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABL70920; ABL70920; Pden_2836.
KEGGipde:Pden_2836.
PATRICi22856822. VBIParDen97112_2775.

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiYSHDSHN.
OrthoDBiEOG622PNM.

Enzyme and pathway databases

BioCyciPDEN318586:GCVQ-2878-MONOMER.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Pd 1222.

Entry informationi

Entry nameiADEC_PARDP
AccessioniPrimary (citable) accession number: A1B5X6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: January 23, 2007
Last modified: November 11, 2015
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.