Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A1B587

- IF2_PARDP

UniProt

A1B587 - IF2_PARDP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Translation initiation factor IF-2

Gene

infB

Organism
Paracoccus denitrificans (strain Pd 1222)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi355 – 3628GTPUniRule annotation
Nucleotide bindingi402 – 4065GTPUniRule annotation
Nucleotide bindingi456 – 4594GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: UniProtKB-HAMAP
  2. GTP binding Source: UniProtKB-KW
  3. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPDEN318586:GCVQ-2635-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-2UniRule annotation
Gene namesi
Name:infBUniRule annotation
Ordered Locus Names:Pden_2594
OrganismiParacoccus denitrificans (strain Pd 1222)
Taxonomic identifieri318586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeParacoccus
ProteomesiUP000000361: Chromosome 1

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 848848Translation initiation factor IF-2PRO_1000008293Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi318586.Pden_2594.

Structurei

3D structure databases

ProteinModelPortaliA1B587.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini346 – 514169tr-type GAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni355 – 3628G1By similarity
Regioni380 – 3845G2By similarity
Regioni402 – 4054G3By similarity
Regioni456 – 4594G4By similarity
Regioni492 – 4943G5By similarity

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0532.
HOGENOMiHOG000076907.
KOiK02519.
OMAiESINHVK.
OrthoDBiEOG67HJSV.

Family and domain databases

Gene3Di3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00100_B. IF_2_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 1 hit.
[Graphical view]
SUPFAMiSSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1B587-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDTDGKKPL GLGGGRSGHV KQSFSHGRTH NVVVETKRKR VVVPGKTGAA
60 70 80 90 100
AGGGRSGSPS AVSGDPSKRP AGISDAEMER RMAALRAAKA REVEEAAQRI
110 120 130 140 150
ADEKAREEER ERRRLELEAK EREEREREEA LRLKAEEDER RAREAELREK
160 170 180 190 200
KKAEIAKPKT EARPATPADR AAAEAAAVRA ETKGVSAAGP RKTDRDRDTR
210 220 230 240 250
GGGGDDRDSR NKGRDDSRRT GKLSLSQALD GEGGRQRSLA AMKRKQEKAR
260 270 280 290 300
QKAMGGNQRA EKQVRDVQLP ETIVVSELAN RMAERTPDVI KSLMRMGMMV
310 320 330 340 350
TANQSIDADT AELVIDEFGH HAVRVSDADV EQVIDQVEDK PEDLQPRAPI
360 370 380 390 400
ITIMGHVDHG KTSLLDAIRH ANVVAGEAGG ITQHIGAYQV KASNGAVLTF
410 420 430 440 450
LDTPGHAAFT SMRARGAQVT DIVVLVVAAD DAVMPQTVEA INHAKAAKVP
460 470 480 490 500
MIVAINKIDK PAANPQKVRT DLLLHEVVVE AMSGEVQDVE VSAKTGQGLD
510 520 530 540 550
TLLEAIALQA EILELKANPD RPAQGAVIEA QLDVGRGPVA TVLVQNGTLK
560 570 580 590 600
RGDIFVVGEQ WGKVRALIND KGERVDEAGP SVPVEVLGLN GTPEAGDVLN
610 620 630 640 650
VVSTEAQARE IADYRIQAAK DKRAAAGAAI TLDQMLAKAK ADENVAELPV
660 670 680 690 700
VIKADVQGSA EAIVQALEKI GNDEVRVRVL HYGVGAITES DIGLAEASQA
710 720 730 740 750
PVIGFNVRAN APARNAANQK GVEIRYYSII YDLVDDIKAA ASGLLSAEVR
760 770 780 790 800
ENFIGYAEIK EVFRVSGVGN VAGCLVTEGV ARRSAGVRLL RDNVVIHEGT
810 820 830 840
LKTLKRFKDE VKEVQSGQEC GMAFENYDDI RKGDVIEIFE REEVQRQL
Length:848
Mass (Da):91,294
Last modified:January 23, 2007 - v1
Checksum:iB7DB50802DADE02D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000489 Genomic DNA. Translation: ABL70681.1.
RefSeqiYP_916377.1. NC_008686.1.

Genome annotation databases

EnsemblBacteriaiABL70681; ABL70681; Pden_2594.
GeneIDi4580693.
KEGGipde:Pden_2594.
PATRICi22856319. VBIParDen97112_2524.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000489 Genomic DNA. Translation: ABL70681.1 .
RefSeqi YP_916377.1. NC_008686.1.

3D structure databases

ProteinModelPortali A1B587.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 318586.Pden_2594.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABL70681 ; ABL70681 ; Pden_2594 .
GeneIDi 4580693.
KEGGi pde:Pden_2594.
PATRICi 22856319. VBIParDen97112_2524.

Phylogenomic databases

eggNOGi COG0532.
HOGENOMi HOG000076907.
KOi K02519.
OMAi ESINHVK.
OrthoDBi EOG67HJSV.

Enzyme and pathway databases

BioCyci PDEN318586:GCVQ-2635-MONOMER.

Family and domain databases

Gene3Di 3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00100_B. IF_2_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR013575. IF2_assoc_dom_bac.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view ]
PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 2 hits.
PF11987. IF-2. 1 hit.
PF08364. IF2_assoc. 1 hit.
PF04760. IF2_N. 1 hit.
[Graphical view ]
SUPFAMi SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Pd 1222.

Entry informationi

Entry nameiIF2_PARDP
AccessioniPrimary (citable) accession number: A1B587
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3