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A1B576 (A1B576_PARDP) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Pden_2583
OrganismParacoccus denitrificans (strain Pd 1222) [Complete proteome] [HAMAP] EMBL ABL70670.1
Taxonomic identifier318586 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Paracoccus

Protein attributes

Sequence length343 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2131Iron By similarity HAMAP MF_00323
Metal binding2941Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
A1B576 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 44ACA34049931490

FASTA34338,770
        10         20         30         40         50         60 
MTLPEHAPAS QPQSPARKIG VLIANLGTPD SPDYWPMRRY LSEFLSDKRV IDYPAWKWQP 

        70         80         90        100        110        120 
LLQTVILTKR PFTSGANYRL IWNNEANESP LMTITKQQVA ALRERTAALW GDRVMVDFCM 

       130        140        150        160        170        180 
RYGNPSTPDV VERMVKAGCD RILFFPLYPQ YAGATTATAN DQFFRALMGQ KAQPAARTVP 

       190        200        210        220        230        240 
PYFDRPDYIA ALAASVERAL GGRQPRKLVA SYHGMPRRYF EEGDPYFLQC TETSRLLRER 

       250        260        270        280        290        300 
LGWDEDVIDT TFQSVFGTEE WLRPYTVEHV AELAQRGITE IAVISPAFSA DCIETLEEIQ 

       310        320        330        340 
GEIREAFIHA GGKEFTYIPC LNAEPDHIDV LTAVIGENLG GWV

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References

[1]"Complete sequence of chromosome 1 of Paracoccus denitrificans PD1222."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Spiro S., Richardson D.J., Moir J.W.B., Ferguson S.J., van Spanning R.J.M., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000489 Genomic DNA. Translation: ABL70670.1.
RefSeqYP_916366.1. NC_008686.1.

3D structure databases

ProteinModelPortalA1B576.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1B576.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4579888.
GenomeReviewsGene locus Pden_2583 in contig CP000489_GR.
KEGGpde:Pden_2583.
PATRIC22856297. VBIParDen97112_2513.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0276.
HOGENOMHBG697135.
OMAIRPAKSA.
PhylomeDBA1B576.
ProtClustDBPRK00035.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1B576_PARDP
AccessionPrimary (citable) accession number: A1B576
Entry history
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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