A1B397 (A1B397_PARDP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Choline dehydrogenase RuleBase RU003969
EC=1.1.99.1 RuleBase RU003969

Gene names

Ordered Locus Names:

Pden_1896

Organism

Paracoccus denitrificans (strain Pd 1222) [Complete proteome] [HAMAP] EMBL ABL69991.1

Taxonomic identifier

318586 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Paracoccus

Protein attributes

Sequence length	550 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. SAAS SAAS007867
Catalytic activity	Choline + acceptor = betaine aldehyde + reduced acceptor. RuleBase RU003969 SAAS SAAS007867
Cofactor	FAD By similarity. SAAS SAAS007867 RuleBase RU003968
Pathway	Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. RuleBase RU003969 SAAS SAAS007867
Sequence similarities	Belongs to the GMC oxidoreductase family. RuleBase RU003968

Ontologies

Keywords
Ligand	FAD SAAS SAAS011533 Flavoprotein SAAS SAAS011533 RuleBase RU003968
Molecular function	Oxidoreductase SAAS SAAS007867
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: InterPro
Molecular function	choline dehydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1B397 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: EE9066AA1C1FAF6B	FASTA	550	60,412
	10 20 30 40 50 60 MIPDYVIVGA GSAGCALAYR LVMAGKRVDI IEYGGSDVGP FIQMPAALSY PMNMRRYDWG 70 80 90 100 110 120 FSSEPEPHLG RRRLVTPRGK VVGGSSSING MVFVRGHARD FDFWAESGAG GWAYADVLPY 130 140 150 160 170 180 FKRMESSHGA VSDYRGTEGP LHVTRGSRKN PLFNAFIRAG REAGYPTTED YNGARQEGFG 190 200 210 220 230 240 AMEATIWEGR RWSAANAYLR PAQETGQLRL RRGLAQRVVF EDGRAVGVEV KNSRGVNVFR 250 260 270 280 290 300 AKHEVILSAS SINTPKLLML SGIGPAEHLA EHGIAVRADR PGVGANLQDH LEVYMQYTAT 310 320 330 340 350 360 KPITLYKHWN LWGKGSIGAQ WLATGTGLGA SNQFESCGFI RSAAGVEYPD IQYHFLPLAV 370 380 390 400 410 420 RYDGKAAAEG HGFQVHVGPM RSKSRGTVRL KSADPRQAPE IRFNYMSHPD DWAEFRACVR 430 440 450 460 470 480 LTREIFEQPA FAEYKGYEIQ PGEEVVSDEQ IDAFIREHAE SAFHPCGTAR MGRADDPMAV 490 500 510 520 530 540 VDPELRVIGV EGLRVADSSI FPRITNGNLN APSIMTGEKA ADHILGQGML APLNLGPEIS 550 PDWEKLQRSA

References

[1]

"Complete sequence of chromosome 1 of Paracoccus denitrificans PD1222." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Spiro S., Richardson D.J., Moir J.W.B., Ferguson S.J., van Spanning R.J.M., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000489 Genomic DNA. Translation: ABL69991.1.
RefSeq	YP_915687.1. NC_008686.1.
3D structure databases
ProteinModelPortal	A1B397.
ModBase	Search...
Protein-protein interaction databases
STRING	A1B397.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4581116.
GenomeReviews	Gene locus Pden_1896 in contig CP000489_GR.
KEGG	pde:Pden_1896.
PATRIC	22854901. VBIParDen97112_1831.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2303.
HOGENOM	HBG734713.
OMA	GPFIQMP.
PhylomeDB	A1B397.
ProtClustDB	PRK02106.
Family and domain databases
InterPro	IPR011533. Choline_dehydrogenase. IPR012132. GMC_OxRdtase. IPR000172. GMC_OxRdtase_N. IPR007867. GMC_OxRtase_C. [Graphical view]
KO	K00108.
Pfam	PF05199. GMC_oxred_C. 1 hit. PF00732. GMC_oxred_N. 1 hit. [Graphical view]
PIRSF	PIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMs	TIGR01810. BetA. 1 hit.
PROSITE	PS00623. GMC_OXRED_1. 1 hit. PS00624. GMC_OXRED_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1B397_PARDP

Accession

Primary (citable) accession number: A1B397

Entry history

Integrated into UniProtKB/TrEMBL:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)