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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Paracoccus denitrificans (strain Pd 1222)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPDEN318586:G1GW1-1879-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Pden_1870
OrganismiParacoccus denitrificans (strain Pd 1222)
Taxonomic identifieri318586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeParacoccus
Proteomesi
  • UP000000361 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000180831 – 581Arginine--tRNA ligaseAdd BLAST581

Proteomic databases

PRIDEiA1B373

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi318586.Pden_1870

Structurei

3D structure databases

ProteinModelPortaliA1B373
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi131 – 141"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A1B373-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLFSDIRTL VIGALAQMEQ AGELPAGLDT ANVTVEPPRD AAHGDMATNA
60 70 80 90 100
AMVLAKPAGK KPRDIAEALA ARLAADPRIA SAEVAGPGFL NLRLVSGEWQ
110 120 130 140 150
SVVRAALAEG GDYGRSEMGR GQRINVEFVS ANPTGPMHVG HTRGAVFGDA
160 170 180 190 200
LAALLDFSGH EVTREYYIND GGAQVDVLAR SAYERYREAN GLEPEIREGL
210 220 230 240 250
YPGDYLIPVG EALKTKYGET LLDKPEEEWL AEVRDFATRA MMDMIREDLA
260 270 280 290 300
LLNVHMDVFS SEKALYGTGR IEAAIERLRQ AGLIYEGVLE PPKGKTPEDW
310 320 330 340 350
EPREQTLFRS TAHGDDVDRP VKKSDGSWTY FAPDIAYHWD KIERGYDALI
360 370 380 390 400
DVFGADHGGY VKRMTAAVKA LSDGRVPLDV KLIQLVRLFK NGEPFKMSKR
410 420 430 440 450
AGTFVTLRDV VEQAGADVTR FHMLTRKNDA ALDFDFARVL EQSKDNPVWY
460 470 480 490 500
VQYASARVNS VLNKAAGMGV DTTDAALAQA DLAQLSHPAE LELARKVAEW
510 520 530 540 550
PRTVEIAARA HEPHRIAFFL YDIASELHSL WNRGNDEPAL RFLQEGDPAA
560 570 580
MAAKIALARS VGVVISAGLG ILGVTPAKEM R
Length:581
Mass (Da):63,562
Last modified:January 23, 2007 - v1
Checksum:i62A9B7CFEC22081B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000489 Genomic DNA Translation: ABL69967.1
RefSeqiWP_011748164.1, NC_008686.1

Genome annotation databases

EnsemblBacteriaiABL69967; ABL69967; Pden_1870
KEGGipde:Pden_1870

Similar proteinsi

Entry informationi

Entry nameiSYR_PARDP
AccessioniPrimary (citable) accession number: A1B373
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 23, 2007
Last modified: June 20, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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