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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Paracoccus denitrificans (strain Pd 1222)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].UniRule annotation
L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BioCyciPDEN318586:G1GW1-1271-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:Pden_1270
OrganismiParacoccus denitrificans (strain Pd 1222)
Taxonomic identifieri318586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeParacoccus
Proteomesi

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003043461 – 212Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST212

Proteomic databases

PRIDEiA1B1I1

Interactioni

Protein-protein interaction databases

STRINGi318586.Pden_1270

Structurei

3D structure databases

ProteinModelPortaliA1B1I1
SMRiA1B1I1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z Bacteria
COG2360 LUCA
HOGENOMiHOG000102326
KOiK00684
OMAiYRQGIFP
OrthoDBiPOG091H045I

Family and domain databases

HAMAPiMF_00688 Leu_Phe_trans, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR004616 Leu/Phe-tRNA_Trfase
PANTHERiPTHR30098 PTHR30098, 1 hit
PfamiView protein in Pfam
PF03588 Leu_Phe_trans, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR00667 aat, 1 hit

Sequencei

Sequence statusi: Complete.

A1B1I1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGGLTAERM LAAYAQGVFP MAESASAAQL YWFEPALRGI LPVGGVHVSR
60 70 80 90 100
SMRRFLRHCD WRATIDNDFA GVVAGCADRE ETWINAPLLA LYQDLFRMGH
110 120 130 140 150
AHSLEIRAGE DLIGGMFGLT LGGAFFAESM FSRRSNASKA ALIWMSSHLA
160 170 180 190 200
RCGFTLWDTQ YPNPHLASMG GRAIPRLEYR RRLAAALRIP ADFTAHALPD
210
VQALLQEITQ TS
Length:212
Mass (Da):23,343
Last modified:January 23, 2007 - v1
Checksum:iE2308CB7BFF9DFB3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000489 Genomic DNA Translation: ABL69375.1
RefSeqiWP_011747593.1, NC_008686.1

Genome annotation databases

EnsemblBacteriaiABL69375; ABL69375; Pden_1270
KEGGipde:Pden_1270

Similar proteinsi

Entry informationi

Entry nameiLFTR_PARDP
AccessioniPrimary (citable) accession number: A1B1I1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 66 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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