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A1B1H7 (CLPX_PARDP) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
ATP-dependent Clp protease ATP-binding subunit ClpX
Gene names
Name:clpX
Ordered Locus Names:Pden_1266
OrganismParacoccus denitrificans (strain Pd 1222) [Complete proteome] [HAMAP]
Taxonomic identifier318586 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeParacoccus

Protein attributes

Sequence length421 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP By similarity. HAMAP-Rule MF_00175

Subunit structure

Heterodimer of ClpP and ClpX By similarity. HAMAP-Rule MF_00175

Sequence similarities

Belongs to the ClpX chaperone family.

Ontologies

Keywords
   DomainZinc-finger
   LigandATP-binding
Metal-binding
Nucleotide-binding
Zinc
   Molecular functionChaperone
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotein folding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

nucleoside-triphosphatase activity

Inferred from electronic annotation. Source: InterPro

zinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 421421ATP-dependent Clp protease ATP-binding subunit ClpX HAMAP-Rule MF_00175
PRO_1000024605

Regions

Zinc finger15 – 4026C4-type HAMAP-Rule MF_00175
Nucleotide binding117 – 1248ATP Potential

Sequences

Sequence LengthMass (Da)Tools
A1B1H7 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 1BBDEC856945C295

FASTA42145,925
        10         20         30         40         50         60 
MANPTGGDSK NTLYCSFCGK SQHEVRKLIA GPTVFICDEC VELCMDIIRE ETKSSALKSG 

        70         80         90        100        110        120 
DGVPTPREIC NVLDDYVIGQ EHAKRVLSVA VHNHYKRLNH SSKTDIELAK SNILLIGPTG 

       130        140        150        160        170        180 
CGKTLLAQTL ARILDVPFTM ADATTLTEAG YVGEDVENII LKLLQASEYN VERAQRGIVY 

       190        200        210        220        230        240 
IDEVDKITRK SDNPSITRDV SGEGVQQALL KIMEGTVASV PPQGGRKHPQ QEFLQVDTTN 

       250        260        270        280        290        300 
ILFICGGAFA GLDRIIAQRN KGTAMGFGAA VKEDDDKGVG ELFKQLEPED LLKFGLIPEF 

       310        320        330        340        350        360 
VGRLPVIATL GDLDEQALIT ILTQPKNALV KQYQRLFDLE SVKLTFTEDA LTAIAKRAIK 

       370        380        390        400        410        420 
RKTGARGLRS IMEDILLDTM FDLPGMDSVE EVVVNEEAVD NPTAKPLLIH TDSKKETASA 


G 

« Hide

References

[1]"Complete sequence of chromosome 1 of Paracoccus denitrificans PD1222."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Spiro S., Richardson D.J., Moir J.W.B., Ferguson S.J., van Spanning R.J.M., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Pd 1222.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000489 Genomic DNA. Translation: ABL69371.1.
RefSeqYP_915067.1. NC_008686.1.

3D structure databases

ProteinModelPortalA1B1H7.
SMRA1B1H7. Positions 13-51.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING318586.Pden_1266.

Proteomic databases

PRIDEA1B1H7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABL69371; ABL69371; Pden_1266.
GeneID4580305.
KEGGpde:Pden_1266.
PATRIC22853679. VBIParDen97112_1232.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1219.
HOGENOMHOG000010093.
KOK03544.
OMALDTMFDL.
OrthoDBEOG625JZK.
ProtClustDBPRK05342.

Enzyme and pathway databases

BioCycPDEN318586:GCVQ-1281-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 2 hits.
HAMAPMF_00175. ClpX.
InterProIPR003593. AAA+_ATPase.
IPR013093. ATPase_AAA-2.
IPR019489. Clp_ATPase_C.
IPR004487. Clp_protease_ATP-bd_su_ClpX.
IPR027417. P-loop_NTPase.
IPR010603. Znf_CppX_C4.
[Graphical view]
PfamPF07724. AAA_2. 1 hit.
PF10431. ClpB_D2-small. 1 hit.
PF06689. zf-C4_ClpX. 1 hit.
[Graphical view]
SMARTSM00382. AAA. 1 hit.
SM01086. ClpB_D2-small. 1 hit.
SM00994. zf-C4_ClpX. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00382. clpX. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCLPX_PARDP
AccessionPrimary (citable) accession number: A1B1H7
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 23, 2007
Last modified: April 16, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families