A1B1C3 (URED_PARDP) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease accessory protein UreD

Gene names

Name:	ureD
Ordered Locus Names:	Pden_1212

Organism

Paracoccus denitrificans (strain Pd 1222) [Complete proteome] [HAMAP]

Taxonomic identifier

318586 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Paracoccus

Protein attributes

Sequence length	279 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter By similarity. HAMAP MF_01384
Subunit structure	UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_01384.
Sequence similarities	Belongs to the UreD family.

Ontologies

Keywords
Biological process	Nickel insertion
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nickel cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 279	279	Urease accessory protein UreD HAMAP MF_01384		PRO_0000340470

Sequences

	Sequence		Length	Mass (Da)
	A1B1C3 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: 13E59471F3D2224D	FASTA	279	30,390
	10 20 30 40 50 60 MRGRRLSGPM FDAIAPIRMQ RSRGAASVRL GPRGIEDLAQ SGSAKAMLPR MTAGRPEIVF 70 80 90 100 110 120 LNTAGGLASG DRLDYRIELA PRTQALATTQ TAERAYRAKD APAQIRLHLQ VGEGGWLDWL 130 140 150 160 170 180 PQETILYDGA RLGRETAVDL APGAGCLLLE PIILGRLAMG ETIRHLQLTD RRIVRQDGRM 190 200 210 220 230 240 IHHDALALDD AALSRLHHPA MLGKARAMAS LALIAPHAAD LLEPARAVLD EPGVTGAASA 250 260 270 PPGRLILRLL ADDGWPLRRQ VIRLLRVLRP DPLPRIWQV

References

[1]

"Complete sequence of chromosome 1 of Paracoccus denitrificans PD1222." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. , Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Spiro S., Richardson D.J., Moir J.W.B., Ferguson S.J., van Spanning R.J.M., Richardson P. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Pd 1222.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000489 Genomic DNA. Translation: ABL69317.1.
RefSeq	YP_915013.1. NC_008686.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1B1C3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4578594.
GenomeReviews	Gene locus Pden_1212 in contig CP000489_GR.
KEGG	pde:Pden_1212.
PATRIC	22853589. VBIParDen97112_1188.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0829.
HOGENOM	HBG711156.
OMA	QETILFD.
ProtClustDB	CLSK940836.
Family and domain databases
HAMAP	MF_01384. UreD. [Tree]
InterPro	IPR002669. UreD. [Graphical view]
KO	K03190.
Pfam	PF01774. UreD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

URED_PARDP

Accession

Primary (citable) accession number: A1B1C3

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	January 23, 2007
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program